Cboe Global Markets, Inc.

Why did I receive these proxy materials?

Our Board is asking for your proxy in connection with the Annual Meeting. By giving us your proxy, you

authorize the proxyholders (Craig S. Donohue and Patrick Sexton) to vote your shares at the Annual Meeting

according to the instructions that you provide. If the Annual Meeting is adjourned or postponed, your proxy will

be used to vote your shares when the meeting reconvenes.

Our 2025 Annual Report to Stockholders, which includes a copy of our Annual Report on Form 10-K for the year

ended December 31, 2025 (excluding exhibits), as filed with the SEC, is being mailed to stockholders with this

Proxy Statement.

Who can vote at the Annual Meeting?

You are entitled to vote your shares of our common stock if you were a stockholder at the close of business on

March 19, 2026, the record date for the Annual Meeting. On that date, there were 104,742,273 shares of our

common stock outstanding. Therefore, there are 104,742,273 shares of voting common stock outstanding, each

of which entitles the holder to 1 vote for each matter to be voted on at the Annual Meeting. Our outstanding

common stock is held by approximately 95 stockholders of record as of March 19, 2026. A list of stockholders of

record will be open for examination by any stockholder for any purpose germane to the Annual Meeting for a

period of 10 days prior to the Annual Meeting at our principal executive offices at 433 West Van Buren Street,

Chicago, Illinois 60607.

Who is and is not a stockholder of record?

If you hold shares of common stock registered in your name at our transfer agent, Broadridge Corporate Issuer

Solutions, Inc. ("Broadridge"), you are a stockholder of record.

If you hold shares of common stock indirectly through a broker, bank, or similar institution, or are an employee

or director who holds shares of restricted stock at Fidelity, you are not a stockholder of record, but instead hold

in "street name". Please see the information under the heading"If I hold my shares in "street name" and do

not provide voting instructions, can my broker still vote my shares?" for important information.

If you are a stockholder of record, Broadridge is sending these proxy materials to you directly. If you hold shares

in street name, these materials are being provided to you by the broker, bank, or similar institution through

which you hold your shares.

What do I need to do to attend the Annual Meeting?

The Annual Meeting will be a completely virtual meeting of stockholders, which will be conducted via live audio

webcast. The live audio webcast of the Annual Meeting will also be available for listening to the general public,

but participation in the Annual Meeting, including voting shares and submitting questions, will be limited to

stockholders. You are entitled to participate in the Annual Meeting only if you were a stockholder at the close of

business on March 19, 2026, the record date for the Annual Meeting, or if you hold a valid proxy to vote at the

Annual Meeting.

If you were a stockholder of record as of the close of business on March 19, 2026, or you hold a valid proxy for

the Annual Meeting, you will be able to attend the Annual Meeting via live audio webcast, vote your shares, and

submit your questions during the meeting by visiting www.virtualshareholdermeeting.com/CBOE2026. To

participate, you will need your 16-digit control number included in your proxy materials, on your proxy card, or

on the instructions that accompanied your proxy materials.

If you were not a stockholder of record, but you hold shares in street name and you want to attend the Annual

Meeting via live audio webcast, vote your shares, and submit your questions during the meeting by visiting

www.virtualshareholdermeeting.com/CBOE2026, you must obtain, from the broker, bank, or other organization

that holds your shares, the information required, including a 16-digit control number, and you may be required to

provide proof of beneficial ownership, such as your most recent account statement as of the record date, a copy

of the voting instruction form provided by your broker, bank, trustee, or nominee, or other similar evidence of

ownership.

If you are not a stockholder or if you have lost your 16-digit control number, you will be able to listen to the live

audio webcast of the Annual Meeting by visiting www.virtualshareholdermeeting.com/CBOE2026, but you will

not be able to vote or submit your questions during the meeting.

The Annual Meeting will begin promptly at 8:00 a.m., Central time. We encourage you to access the meeting

prior to the start time. Online access will open at 7:45 a.m., Central time, and you should allow ample time to log

in to the meeting live audio webcast and test your computer audio system.

We recommend that you carefully review the procedures needed to gain admission in advance. If you do not

comply with the procedures described here for attending the Annual Meeting via live audio webcast, you will not

be able to participate online.

Please contact Investor Relations at investorrelations@Cboe.com or (312) 786-7559 in advance of the Annual

Meeting if you have questions about attending the Annual Meeting.

If I am unable to attend the live audio webcast of the Annual Meeting, may I listen at a later date?

Yes, an audio replay of the Annual Meeting will be posted and publicly available on the Events and

Presentations page of our Investor Relations website at http://ir.Cboe.com. This audio replay will cover the

entire Annual Meeting, including each stockholder question addressed during the Annual Meeting.

What if during the check-in period or during the Annual Meeting I have technical difficulties or trouble

accessing the virtual meeting live audio webcast?

During online check-in and continuing through the length of the virtual Annual Meeting, we will have technicians

standing by to assist you with any technical difficulties you may have accessing the live audio webcast. If you

encounter any difficulties accessing the Annual Meeting during the check-in or at meeting time, please call (844)

986-0822 (U.S.) or (303) 562-9302 (International).

Why is the Annual Meeting being conducted as a virtual meeting via live audio webcast?

We believe a virtual meeting format for the Annual Meeting may facilitate stockholder attendance, dialogue, and

participation by enabling stockholders to participate fully, and equally, from any location around the world, at no

cost. Wewill be able to engage with all stockholders as opposed to just those who can afford to travel to an in-

person meeting. The virtual format will also allow stockholders to submit questions and comments during the

meeting.

We are utilizing technology from Broadridge, a leading virtual meeting solution. The platform is expected to

accommodate most, if not all, stockholders. Both we and Broadridge will test the platform technology before

going "live" for the Annual Meeting.

How do I submit questions or comments for the Annual Meeting?

Stockholders can submit questions or comments online during the Annual Meeting via live audio webcast by

visiting www.virtualshareholdermeeting.com/CBOE2026. We will answer timely submitted questions or

comments on a matter to be voted on at the Annual Meeting before voting is closed on the matter. Then, we will

address appropriate general questions or comments from stockholders regarding the Company. Questions or

comments received during the Annual Meeting will be presented as submitted, uncensored and unedited,

except that we may omit certain personal details for data protection issues or we may edit profanity or other

inappropriate language. Questions or comments regarding general economic, political, or other views that are

not directly related to the business of the meeting, that are of an individual concern to a stockholder or that are

not an appropriate subject matter for general discussion, are not pertinent to the meeting and therefore will not

be presented. If we receive substantially similar questions, we may group those questions together and provide

a single response to avoid repetition.

How do I vote?

You may cast your vote in one of four ways:

By Internet before the Annual Meeting. The web address for Internet voting is www.proxyvote.com

and is also on the enclosed proxy card. Internet voting is available 24 hours a day.

By Internet during the Annual Meeting. You may vote online during the Annual Meeting (see"What

do I need to do to attend the Annual Meeting?"). However, even if you plan to participate in the

Annual Meeting via live audio webcast, we recommend that you also vote by Internet as described

above so that your votes will be counted if you later decide not to participate in the Annual Meeting.

By Telephone. The number for telephone voting is 1-800-690-6903 and is also on the enclosed proxy

card. Telephone voting is available 24 hours a day.

By Mail. Mark the enclosed proxy card, sign and date it, and return it in the pre-paid envelope we have

provided.

If you choose to vote by Internet before or during the Annual Meeting or by telephone, then you do not need to

return the proxy card. To be valid, your vote by Internet before the Annual Meeting or telephone must be

received by 11:59 p.m., Eastern time, on May 13, 2026 for shares held directly, the deadline specified on the

proxy card. If you vote by Internet before the Annual Meeting or telephone and subsequently obtain a legal

proxy from your account representative, then your prior vote will be revoked regardless of whether you vote that

legal proxy.

The Internet and telephone voting procedures are designed to authenticate stockholders' identities, allow

stockholders to give their voting instructions, and confirm that stockholders' instructions have been recorded

properly. Stockholders voting by Internet or telephone should understand that, while we do not charge any fees

for voting by Internet or telephone, there may nevertheless be costs that must be borne by you.

May I change my vote?

If you are a stockholder of record, you may revoke your proxy or change your vote at any time before it is voted

at the Annual Meeting by:

Submitting a new proxy by telephone or through the Internet, after the date of the earlier voted proxy,

Returning a signed proxy card dated later than your last proxy,

Submitting a written revocation to the Corporate Secretary of Cboe Global Markets, Inc. at 433 West

Van Buren Street, Chicago, Illinois 60607, or

Voting online during the Annual Meeting.

If you are a stockholder of record and need a new proxy card, to change your vote or otherwise, please contact

the Corporate Secretary at the address above or via email at CorporateSecretary@Cboe.com.

If your bank, broker, or other nominee holds your shares in "street name", you may revoke your proxy or change

your vote only by following the separate instructions provided by your bank, broker, or nominee.

If I submit a proxy by Internet, telephone or mail, how will my shares be voted?

If you properly submit your proxy by one of these methods, and you do not subsequently revoke your proxy,

your shares of common stock will be voted in accordance with your instructions.

If you sign, date, and return your proxy card but do not give voting instructions, your shares of common stock

will be voted as follows:

FOR the election of each of our director nominees,

FOR the advisory vote to approve the compensation paid to our executive officers,

FOR the ratification of the appointment of KPMG as our independent registered public accounting firm

for our 2026 fiscal year, and

AGAINST the stockholder proposal regarding the shareholder right to act by written consent.

In addition, if you properly submit your proxy by one of these methods, and you do not subsequently revoke

your proxy, and any other matters are properly presented at the Annual Meeting, your shares of common stock

will be voted in accordance with the judgment of the persons voting the proxy on such matters. We are not

aware of any other matters that will be considered at the Annual Meeting.

If I hold my shares in "street name" and do not provide voting instructions, can my broker still vote my

shares?

Under the rules of various securities exchanges, brokers that have not received voting instructions from their

customers 10 days prior to the meeting date may vote their customers' shares in the brokers' discretion on the

proposal regarding the ratification of the appointment of KPMG as our independent registered public accounting

firm for our 2026 fiscal year, because the rules of the exchanges currently deem this a "discretionary" matter.

Absent instruction, brokers will not be able to vote on any of the other matters included in this Proxy Statement.

If brokers exercise their discretion in voting on the proposal regarding the ratification of KPMG, a "broker non-

vote" will occur as to the other matters presented for a vote at the Annual Meeting, unless you provide voting

instructions.

What vote is required for adoption or approval of each matter?

Election of Directors. You may vote FOR or AGAINST each of the director nominees or you may ABSTAIN.

Each nominee must receive the affirmative vote of a majority of the votes properly cast with respect to his or her

election in order to be elected. Each nominee has tendered his or her resignation, contingent on failing to

receive a majority of the votes cast in this election and acceptance by the Board. In the event any director fails

to receive a majority of votes cast, the Nominating and Governance Committee will consider and make a

recommendation to the Board as to whether to accept the resignation.

Advisory Vote to Approve Executive Compensation. You may vote FOR or AGAINST the advisory proposal

to approve our executive compensation or you may ABSTAIN. A majority of the shares of common stock

properly cast upon this proposal must be voted FOR approval of this advisory proposal for it to pass. Votes cast

FOR or AGAINST with respect to the proposal will be counted as shares cast on the proposal.

Ratification of the Appointment of our Independent Registered Public Accounting Firm. You may vote

FOR or AGAINST the ratification of the appointment of our independent registered public accounting firm or you

may ABSTAIN. A majority of the shares of common stock properly cast upon this proposal must be voted FOR

ratification for it to pass. Votes cast FOR or AGAINST with respect to this matter will be counted as shares cast

on the matter.

Stockholder Proposal Regarding the Shareholder Right to Act by Written Consent. You may vote FOR or

AGAINST the stockholder proposal regarding the shareholder right to act by written consent or you may

ABSTAIN. A majority of the shares of common stock properly cast upon this proposal must be voted FOR

approval of this proposal for it to pass. Votes cast FOR or AGAINST with respect to the proposal will be counted

as shares cast on the proposal.

Abstentions and Broker Non-Votes. Abstentions and broker non-votes will not be considered a vote cast

either for or against any of the matters being presented in this Proxy Statement and will not impact the voting

results. If you do not provide your broker with voting instructions, the broker cannot vote your shares on any

matter other than the ratification of the appointment of our independent registered public accounting firm. A

"broker non-vote" occurs when your broker submits a proxy for the meeting with respect to discretionary

matters, but does not vote on non-discretionary matters because you did not provide voting instructions on

these matters. In the case of a discretionary matter (i.e., the ratification of the appointment of our independent

registered public accounting firm), your broker is permitted to vote your shares of common stock even when you

have not given voting instructions (as described above under "If I hold my shares in "street name" and do

not provide voting instructions, can my broker still vote my shares?").

How many votes are required to transact business at the Annual Meeting?

A quorum is required to transact business at the Annual Meeting. The holders of a majority of the outstanding

shares of our common stock as of March 19, 2026, present or represented by proxy and entitled to vote, will

constitute a quorum for the transaction of business at the Annual Meeting. Abstentions and broker non-votes are

treated as present for quorum purposes.

What happens if the meeting is postponed or adjourned or encounters technical difficulties?

Your proxy will remain valid and may be voted at the postponed or adjourned meeting. You will be able to

change or revoke your proxy until it is voted. If there are any technical issues in convening or hosting the

meeting, we will promptly post information to our Investor Relations website, including information on when the

meeting will be reconvened.

How do I obtain more information about Cboe Global Markets, Inc.?

A copy of our 2025 Annual Report to Stockholders, which includes our Annual Report on Form 10-K, is enclosed

with this Proxy Statement. The 2025 Annual Report, our Annual Report on Form 10-K for the fiscal year ended

December 31, 2025 filed with the SEC, our Corporate Governance Guidelines, our Code of Business Conduct

and Ethics, and the charters for our Audit, Compensation and Human Capital, and Nominating and Governance

Committees are available on our website at http://ir.Cboe.com. In addition, we intend to disclose any future

amendments to certain provisions of our Code of Business Conduct and Ethics, or any waivers of such

provisions, applicable to any principal executive officer, principal financial officer, principal accounting officer or

controller, or persons performing similar functions on our website at http://ir.Cboe.com.

These documents may also be obtained, free of charge, by writing to: Cboe Global Markets, Inc., 433 West Van

Buren Street, Chicago, Illinois 60607, Attn: Investor Relations; or by sending an e-mail to:

investorrelations@Cboe.com.

These documents, as well as other information about us, are also available on our website at http://ir.Cboe.com.

Information on our website does not form a part of this Proxy Statement.

How do I sign up for electronic delivery of proxy materials?

This Proxy Statement and our 2025 Annual Report to Stockholders are available on our website at http://

ir.Cboe.com. If you would like to help reduce our costs of printing and mailing future materials, you can consent

to access these documents in the future over the Internet rather than receiving printed copies in the mail.

If you are a stockholder of record, you may sign up for this service by contacting our transfer agent in writing at

Broadridge, 51 Mercedes Way, Edgewood, NY 11717 or calling (866) 301-8223. If you hold shares of common

stock in "street name", you can contact your account representative at the broker, bank, or similar institution

through which you hold your shares for information regarding electronic delivery of future materials. Your

consent to electronic delivery will remain in effect until you revoke it.

Who pays the expenses of this proxy solicitation?

The Company will pay the expenses of the preparation of our proxy materials and the solicitation of proxies by

the Company for the Annual Meeting. Certain of our directors, officers or employees may make solicitations in

person, telephonically, electronically, or by other means of communication. We have also engaged Sodali & Co

(formerly Morrow Sodali LLC) to assist in the solicitation and distribution of proxies. Our directors, officers, and

employees will receive no additional compensation for any such solicitation, and we will pay Sodali & Co a fee

of $10,500 for its services, as well as reimbursements for certain expenses. We will request that banks,

brokerage houses, and other custodians, nominees, and fiduciaries forward all of our solicitation materials to the

beneficial owners of the shares that they hold of record. We will reimburse these record holders for customary

clerical and mailing expenses incurred by them in forwarding these materials to customers.

If you have any questions about the Annual Meeting or need additional copies of this Proxy Statement or

additional proxy cards, please contact Sodali & Co at 333 Ludlow St, 5th Floor, South Tower, Stamford,

Connecticut 06902. Banks and brokerage firms may call (203) 658-9400 and stockholders may call toll-free at

(800) 662-5200 or by sending an e-mail to: CBOE.info@sodali.com.

Who will count the vote?

The Company has engaged Broadridge to serve as the inspector of elections for the Annual Meeting. As

inspector of elections, Broadridge will tabulate the voting results.

What does it mean if I get more than one proxy or voting instruction card?

If your shares are registered in more than one name or in more than one account, you will receive more than

one card. This may occur if you hold common stock in multiple accounts, such as with different brokers in street

name and as the record holder with Broadridge. Please complete and return all of the proxy or voting instruction

cards that you receive (or vote by telephone or through the Internet all of the shares on all of the proxy or voting

instruction cards received) to ensure that all of your shares are voted.