ATYR
aTyr Pharma, Inc.NASDAQ
Healthcare • Biotechnology
$6.35+5.31%
Close Nov 6, 2026
- Market cap
- $15.57M
- 1 month
- -37.8%
- 3 months
- -70.0%
- 1 year
- -80.5%
- Dividend
- No dividends on record
- Next-quarter EPS estimate
- -$4.00Quarter to Sep 30, 2026 · 7 analysts · -3,844.8% in 30d
- Short interest
- 10.5% of float10.3M shares · settled Oct 15, 2026 · -20.3% since Sep 30, 2026 · FINRA
Fundamentals · trailing 12 months to Jun 30, 2026
- Revenue
- $190K
- Net income
- -$60.81M
- Free cash flow
- -$54.82M
- Book value
- $48.79M
- Total debt
- $11.3M
- P/E
- —
- Price / sales
- 81.9×
- Price / book
- 0.3×
- FCF yield
- -352.1%
- Net margin
- -32,003.7%
EODHD (TTM) · as of Nov 6, 2026
End-of-day close from stored market data, not a live quote.
About aTyr Pharma, Inc.
aTyr Pharma, Inc., a clinical stage biotechnology company, engages in the discovery and development of product candidates that translate tRNA synthetase biology into new therapies for fibrosis and inflammation in the United States.
Read more
Its lead therapeutic candidate efzofitimod, a selective modulator of NRP2 that is in Phase 3 clinical trial for the treatment of pulmonary sarcoidosis; Phase 2 clinical trial to treat Sarcoidosis and systemic sclerosis- interstitial lung disease (ILDs); and treatment of other ILDs, such as chronic hypersensitivity pneumonitis (CHP) and connective tissue disease related ILD. The company develops ATYR0101, a fusion protein derived from a domain of aspartyl-tRNA synthetase, which is in preclinical development for the treatment of fibrosis; ATYR0750, a domain of alanyl-tRNA synthetase for the treatment of liver disorders; and develops and tests ATYR2810, the Company's monoclonal antibody that targets the neuropilin-2 (NRP2) receptor for the treatment of aggressive cancers. It has collaboration and license agreement with Kyorin Pharmaceutical Co., Ltd. for the development and commercialization of efzofitimod for ILDs in Japan. aTyr Pharma, Inc. was incorporated in 2005 and is headquartered in San Diego, California.
- Website
- atyrpharma.com
- Headquarters
- San Diego, CA, United States
- Employees
- 58
- Listed
- May 7, 2015
- Fiscal year ends
- December
Company profile from EODHD, stored Oct 26, 2026.
Quarterly results
The last 8 fiscal quarters as reported (EODHD). Year over year compares the same quarter a year earlier.
| Quarter | Revenue | YoY | Gross margin | Op. income | Net income |
|---|---|---|---|---|---|
| Jun 2026filed Aug 7, 2026 | — | — | — | -$10.9M | -$10.3M |
| Mar 2026filed May 15, 2026 | — | — | — | -$11.4M | -$10.8M |
| Dec 2025filed Mar 5, 2026 | — | — | — | -$14.8M | -$14.0M |
| Sep 2025filed Nov 6, 2025 | $190.0K | — | -11,547.4% | -$26.7M | -$25.7M |
| Jun 2025filed Aug 7, 2025 | — | — | — | -$20.3M | -$19.5M |
| Mar 2025filed May 7, 2025 | — | — | — | -$15.8M | -$14.9M |
| Dec 2024filed Mar 13, 2025 | — | — | — | -$15.8M | -$15.0M |
| Sep 2024filed Nov 7, 2024 | — | — | — | -$18.1M | -$17.3M |
Fiscal years · last 6
| Fiscal year | Revenue | YoY | Gross margin | Op. income | Net income |
|---|---|---|---|---|---|
| Dec 2025filed Mar 5, 2026 | $190.0K | -19.1% | -717.4% | -$77.6M | -$74.1M |
| Dec 2024filed Mar 13, 2025 | $235.0K | -33.4% | — | -$67.9M | -$64.0M |
| Dec 2023filed Mar 14, 2024 | $353.0K | — | — | -$54.9M | -$50.4M |
| Dec 2022filed Mar 14, 2023 | — | — | — | — | — |
| Dec 2021filed Mar 15, 2022 | — | — | — | -$34.0M | -$33.8M |
| Dec 2020filed Mar 24, 2021 | — | — | — | — | — |
Short-interest history
FINRA reports open short positions for a settlement date. The publication date is later. These are reported positions, with a separate date for each observation.
Compare the reported short exposure around the dates you bought, sold or watched ATYR. A long position benefits from price rises; a short position benefits from falls. A change in these counts does not predict either move.
Settlement Oct 15, 2026
10,273,700 shares short
-2,619,308 shares (-20.3%) vs Sep 30, 2026
10.5% of the stored float. Published Oct 26, 2026.
Settlement Sep 30, 2026
12,893,008 shares short
+2,224,851 shares (+20.9%) vs Sep 15, 2026
13.2% of the stored float. Published Oct 9, 2026.
Settlement Sep 15, 2026
10,668,157 shares short
+1,389,124 shares (+15%) vs Aug 31, 2026
11.2% of the stored float. Published Sep 24, 2026.
Settlement Aug 31, 2026
9,279,033 shares short
-162,369 shares (-1.7%) vs Aug 14, 2026
9.7% of the stored float. Published Sep 10, 2026.
Settlement Aug 14, 2026
9,441,402 shares short
-284,654 shares (-2.9%) vs Jul 31, 2026
Share of float unavailable. Published Aug 25, 2026.
Settlement Jul 31, 2026
9,726,056 shares short
+1,448,650 shares (+17.5%) vs Jul 15, 2026
Share of float unavailable. Published Aug 11, 2026.
Change = this settlement’s shares short − the previous recorded settlement’s shares short; percentage change divides by that earlier count. A zero earlier count has no percentage change. Split-spanning counts are left uncompared. Float percentages use the stored settlement observation, not today’s float.
Source: stored FINRA equity short-interest records, up to six settlements from the last 240 days. FINRA data and reporting dates · How to read short interest
Dividends and stock splits
See the recorded cash amounts and dates behind ATYR’s income, and the splits that change its share count. Dates below are stored event records, not confirmation of a payment to your account.
Cash-dividend records
No qualified cash-dividend records are stored. This does not establish that the company pays no dividend.
Up to six Polygon cash-dividend events, including recorded ex-dates within the next 120 days. Amounts retain their recorded currency and decimal precision. Historical amounts are not restated to a common split basis, annualized, or converted to dollars.
For a long holding, compare the ex-date with when you held the shares and check the pay date against your broker’s cash history. Owning the stock today does not establish past entitlement. For a short holding, a dividend can create a payment obligation to the share lender.
Ex-dates and special dividend rules · Short-sale dividend obligations · Dividend data definitions
Split history
1 for 40 · reverse split
Effective Oct 29, 2026
Each 40 pre-split shares become 1 post-split share.
Source: EODHD
1 for 14 · reverse split
Effective Jul 1, 2019
Each 14 pre-split shares become 1 post-split share.
Source: EODHD
Up to six stored split dates through Nov 7, 2026. Equivalent vendor ratios are combined; conflicting ratios are left out. This history may be incomplete.
A split changes the share count and per-share price basis; it does not by itself add investment value. Put your holding’s earlier and later share counts on the same basis before comparing them. This applies to both long shares and shares owed on a short position.
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Smart money context
Holder IQ: MEDIUM
10 smart-money holders: institutions with a high Holder IQ
Q2 2026, filed Sep 22, 2026
Smart-money 13F trend: unchanged (light)
Unlock crowding heatmapUnlock filer discoveryInsider context
Sentiment: unknown
No recent insider trades detected.
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What it means for you
Sign in to read your holdings or watchlist context. No personal position or direction is inferred.
What happened
No directional recent-activity label is available. This context label is separate from the scored insider signal read.
Why it can matter
A count of reported activity describes a sample, not purchase conviction, an insider’s intent or a future price move. Neutral is not an all-clear, and absent direction is not neutral evidence.
How we got this
The current context rule reads at most 50 nonduplicate issuer/share-class records filed in the last 90 days. It counts a bullish direction or purchase code P toward bullish, and a bearish direction or sale code S toward bearish. A side must exceed the opposite count by more than two to set its label; otherwise nonzero directional counts produce neutral. Calculation unavailable for this saved label: its counts, exact records, as-of time and rule version are not supplied here. Do not substitute the separate scored read’s different window or denominator.
Where the data comes from
Stored SEC Forms 3/4/5 insider-signal records, ordered by filing date with amendment duplicates excluded. Filing date is not transaction date. The last-trade line locates recent reported activity; it does not date or reconstruct the complete count.
Red flags: 0
Read the insider context evidence
What it means for you
Sign in to read your holdings or watchlist context. No personal position or direction is inferred.
What happened
No directional recent-activity label is available. This context label is separate from the scored insider signal read.
Why it can matter
A count of reported activity describes a sample, not purchase conviction, an insider’s intent or a future price move. Neutral is not an all-clear, and absent direction is not neutral evidence.
How we got this
The current context rule reads at most 50 nonduplicate issuer/share-class records filed in the last 90 days. It counts a bullish direction or purchase code P toward bullish, and a bearish direction or sale code S toward bearish. A side must exceed the opposite count by more than two to set its label; otherwise nonzero directional counts produce neutral. Calculation unavailable for this saved label: its counts, exact records, as-of time and rule version are not supplied here. Do not substitute the separate scored read’s different window or denominator.
Where the data comes from
Stored SEC Forms 3/4/5 insider-signal records, ordered by filing date with amendment duplicates excluded. Filing date is not transaction date. The last-trade line locates recent reported activity; it does not date or reconstruct the complete count.
Largest 13-F holders · Q2 2026
89 filers reported a long position in ATYR for Q2 2026. 13-F holdings are filed up to 45 days after the quarter ends.
The top 10 hold
74.8%
of the 38.9M shares 13-F filers reported
Moves vs Q1 2026
4 added5 trimmed
1 new
Net shares held
-36.3%
across the 9 holders with a comparable Q1 2026 book
| Rank | Holder | Value | Shares | Shares vs Q1 2026 |
|---|---|---|---|---|
| 1 | FEDERATED HERMES, INC. | $5.1M · 8.5M shares | 8.5M | -19% |
| 2 | VANGUARD CAPITAL MANAGEMENT LLC | $2.3M · 3.8M shares | 3.8M | -0.1% |
| 3 | GSA CAPITAL PARTNERS LLP | $2.1M · 3.5M shares | 3.5M | +105.1% |
| 4 | AQR CAPITAL MANAGEMENT LLC | $1.6M · 2.6M shares | 2.6M | +426.3% |
| 5 | FMR LLC | $1.5M · 2.5M shares | 2.5M | -83.2% |
| 6 | BlackRock, Inc. | $1.1M · 1.8M shares | 1.8M | -71.6% |
| 7 | Kalehua Capital Management LLC | $1.1M · 1.8M shares | 1.8M | New |
| 8 | JANE STREET GROUP, LLC | $1M · 1.7M shares | 1.7M | +3,448.9% |
| 9 | UBS Group AG | $914.1K · 1.5M shares | 1.5M | -60.4% |
| 10 | MORGAN STANLEY | $801.9K · 1.3M shares | 1.3M | +9.6% |
Sign in to see each holder’s Holder IQ, factor-adjusted Holder IQ and rank, and compare these holders with all scored filers. Available on every plan.
Sign in5% holder filings (13D / 13G)
Holders of more than 5% of ATYR file with the SEC within days. A 13D holder may seek to influence the company; a 13G holder is passive. Each holder’s latest filing from the last three years.
| Filed | Holder | % of class |
|---|---|---|
| Nov 4, 2026 | FEDERATED HERMES, INC.13G · passive · amended | 0%under 5% |
| Aug 6, 2026 | FMR LLC13G · passive · amended | 2.5%under 5% |
| Jul 27, 2026 | BlackRock, Inc.13G · passive · amended | 1.8%under 5% |
| Mar 26, 2026 | VANGUARD GROUP INC13G · passive · amended | 0%under 5% |
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