ARWR
Arrowhead Pharmaceuticals IncNASDAQ
Healthcare • Biotechnology
Factor tilt: Mid-Cap Blend
$58.16+1.22%
Close Nov 6, 2026
- Market cap
- $8.19B
- 1 month
- -4.2%
- 3 months
- -34.2%
- 1 year
- +44.3%
- 52-week range
- $38.09$89.59
- Dividend
- No dividends on record
- Short interest
- 9.0% of float11M shares · settled Oct 15, 2026 · +1.8% since Sep 30, 2026 · FINRA
Fundamentals · trailing 12 months to Jun 30, 2026
- Revenue
- $669.5M
- Net income
- -$319.95M
- Free cash flow
- -$75.11M
- Book value
- $465.53M
- Total debt
- $864.07M
- P/E
- —
- Price / sales
- 12.2×
- Price / book
- 17.6×
- FCF yield
- -0.9%
- Net margin
- -47.8%
EODHD (TTM) · as of Nov 6, 2026
End-of-day close from stored market data, not a live quote.
About Arrowhead Pharmaceuticals Inc
Arrowhead Pharmaceuticals, Inc. develops medicines for the treatment of intractable diseases in the United States. Its pipeline includes Plozasiran to reduce production of apolipoprotein C-III in Phase 3 studies; Zodasiran to reduce production of angiopoietin-like protein 3 in Phase 3 clinical trials; ARO-DIMER-PA, a dual functional RNAi molecule in a Phase 1/2a clinical trials; and ARO-PNPLA3, an investigational
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RNAi therapeutic in Phase 1 clinical trials. The company also develops ARO-INHBE, to reduce the hepatic expression of the INHBE gene and its secreted gene product, Activin E in Phase 1/2a clinical trials; ARO-ALK7 to silence adipocyte expression of the ACVR1C gene in Phase 1/2a clinical trials; ARO-RAGE to reduce production of the receptor for advanced glycation end products in Phase 1/2a clinical trials; and ARO-MAPT, an investigational RNAi-based therapy. In addition, it is developing ARO-C3 to reduce production of C3 in Phase 1/2a clinical trials; and ARO-CFB to reduce hepatic expression of CFB in a Phase 1/2a clinical trials. The company has collaboration and license Agreements with Glaxosmithkline Intellectual Property (No. 3) Limited; Takeda Pharmaceutical Company Limited; Amgen Inc.; and Sarepta Therapeutics, Inc. Arrowhead Pharmaceuticals, Inc. was founded in 2003 and is headquartered in Pasadena, California.
- Website
- arrowheadpharma.com
- Headquarters
- Pasadena, CA, United States
- Employees
- 711
- Listed
- Jun 16, 1993
- Fiscal year ends
- September
Company profile from EODHD, stored Oct 22, 2026.
Quarterly results
The last 8 fiscal quarters as reported (EODHD). Year over year compares the same quarter a year earlier.
| Quarter | Revenue | YoY | Gross margin | Op. income | Net income |
|---|---|---|---|---|---|
| Jun 2026filed Aug 4, 2026 | $75.3M | +171.0% | 100.0% | -$170.1M | -$194.3M |
| Mar 2026filed May 7, 2026 | $73.7M | — | — | -$141.3M | -$132.7M |
| Dec 2025filed Feb 5, 2026 | $264.0M | +10,461.3% | — | $40.8M | $30.8M |
| Sep 2025filed Nov 25, 2025 | $256.5M | +987.3% | — | $44.1M | -$23.8M |
| Jun 2025filed Aug 7, 2025 | $27.8M | — | — | -$165.6M | -$175.2M |
| Mar 2025filed May 12, 2025 | — | — | — | — | — |
| Dec 2024filed Feb 10, 2025 | $2.5M | -29.6% | — | -$161.4M | -$173.1M |
| Sep 2024filed Nov 26, 2024 | $23.6M | +46.5% | — | -$162.2M | -$170.5M |
Fiscal years · last 6
| Fiscal year | Revenue | YoY | Gross margin | Op. income | Net income |
|---|---|---|---|---|---|
| Sep 2025filed Nov 25, 2025 | $829.4M | +23,258.2% | — | $98.3M | -$1.6M |
| Sep 2024filed Nov 26, 2024 | $3.6M | -98.5% | -423.7% | -$601.1M | -$599.5M |
| Sep 2023filed Nov 29, 2023 | $240.7M | -1.0% | 94.8% | -$205.0M | -$205.3M |
| Sep 2022filed Nov 28, 2022 | $243.2M | +75.9% | — | -$178.5M | -$176.5M |
| Sep 2021filed Nov 22, 2021 | $138.3M | +57.2% | 100.0% | -$149.0M | -$140.8M |
| Sep 2020filed Nov 23, 2020 | $88.0M | -47.9% | 100.0% | -$93.2M | -$84.6M |
Short-interest history
FINRA reports open short positions for a settlement date. The publication date is later. These are reported positions, with a separate date for each observation.
Compare the reported short exposure around the dates you bought, sold or watched ARWR. A long position benefits from price rises; a short position benefits from falls. A change in these counts does not predict either move.
Settlement Oct 15, 2026
10,959,276 shares short
+198,813 shares (+1.8%) vs Sep 30, 2026
9% of the stored float. Published Oct 26, 2026.
Settlement Sep 30, 2026
10,760,463 shares short
+1,488,173 shares (+16%) vs Sep 15, 2026
8.8% of the stored float. Published Oct 9, 2026.
Settlement Sep 15, 2026
9,272,290 shares short
-154,159 shares (-1.6%) vs Aug 31, 2026
Share of float unavailable. Published Sep 24, 2026.
Settlement Aug 31, 2026
9,426,449 shares short
+219,023 shares (+2.4%) vs Aug 14, 2026
Share of float unavailable. Published Sep 10, 2026.
Settlement Aug 14, 2026
9,207,426 shares short
-448,652 shares (-4.6%) vs Jul 31, 2026
Share of float unavailable. Published Aug 25, 2026.
Settlement Jul 31, 2026
9,656,078 shares short
+20,781 shares (+0.2%) vs Jul 15, 2026
Share of float unavailable. Published Aug 11, 2026.
Change = this settlement’s shares short − the previous recorded settlement’s shares short; percentage change divides by that earlier count. A zero earlier count has no percentage change. Split-spanning counts are left uncompared. Float percentages use the stored settlement observation, not today’s float.
Source: stored FINRA equity short-interest records, up to six settlements from the last 240 days. FINRA data and reporting dates · How to read short interest
Dividends and stock splits
See the recorded cash amounts and dates behind ARWR’s income, and the splits that change its share count. Dates below are stored event records, not confirmation of a payment to your account.
Cash-dividend records
No qualified cash-dividend records are stored. This does not establish that the company pays no dividend.
Up to six Polygon cash-dividend events, including recorded ex-dates within the next 120 days. Amounts retain their recorded currency and decimal precision. Historical amounts are not restated to a common split basis, annualized, or converted to dollars.
For a long holding, compare the ex-date with when you held the shares and check the pay date against your broker’s cash history. Owning the stock today does not establish past entitlement. For a short holding, a dividend can create a payment obligation to the share lender.
Ex-dates and special dividend rules · Short-sale dividend obligations · Dividend data definitions
Split history
1 for 10 · reverse split
Effective Nov 17, 2011
Each 10 pre-split shares become 1 post-split share.
Source: EODHD
1 for 65 · reverse split
Effective Jan 15, 2004
Each 65 pre-split shares become 1 post-split share.
Source: EODHD
Up to six stored split dates through Nov 7, 2026. Equivalent vendor ratios are combined; conflicting ratios are left out. This history may be incomplete.
A split changes the share count and per-share price basis; it does not by itself add investment value. Put your holding’s earlier and later share counts on the same basis before comparing them. This applies to both long shares and shares owed on a short position.
How stock splits workPortfolio context
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Smart money context
Holder IQ: MEDIUM
88 smart-money holders: institutions with a high Holder IQ
Q2 2026, filed Oct 30, 2026
Smart-money 13F trend: distributing (light)
Unlock crowding heatmapUnlock filer discoveryInsider context
Sentiment: neutral
Last trade: sell 79 days ago
Read the insider context evidence
What it means for you
Sign in to read your holdings or watchlist context. No personal position or direction is inferred.
What happened
Stored recent-activity label: neutral. This context label is separate from the scored insider signal read.
Why it can matter
A count of reported activity describes a sample, not purchase conviction, an insider’s intent or a future price move. Neutral is not an all-clear, and absent direction is not neutral evidence.
How we got this
The current context rule reads at most 50 nonduplicate issuer/share-class records filed in the last 90 days. It counts a bullish direction or purchase code P toward bullish, and a bearish direction or sale code S toward bearish. A side must exceed the opposite count by more than two to set its label; otherwise nonzero directional counts produce neutral. Calculation unavailable for this saved label: its counts, exact records, as-of time and rule version are not supplied here. Do not substitute the separate scored read’s different window or denominator.
Where the data comes from
Stored SEC Forms 3/4/5 insider-signal records, ordered by filing date with amendment duplicates excluded. Filing date is not transaction date. The last-trade line locates recent reported activity; it does not date or reconstruct the complete count.
Red flags: 0
Read the insider context evidence
What it means for you
Sign in to read your holdings or watchlist context. No personal position or direction is inferred.
What happened
Stored recent-activity label: neutral. This context label is separate from the scored insider signal read.
Why it can matter
A count of reported activity describes a sample, not purchase conviction, an insider’s intent or a future price move. Neutral is not an all-clear, and absent direction is not neutral evidence.
How we got this
The current context rule reads at most 50 nonduplicate issuer/share-class records filed in the last 90 days. It counts a bullish direction or purchase code P toward bullish, and a bearish direction or sale code S toward bearish. A side must exceed the opposite count by more than two to set its label; otherwise nonzero directional counts produce neutral. Calculation unavailable for this saved label: its counts, exact records, as-of time and rule version are not supplied here. Do not substitute the separate scored read’s different window or denominator.
Where the data comes from
Stored SEC Forms 3/4/5 insider-signal records, ordered by filing date with amendment duplicates excluded. Filing date is not transaction date. The last-trade line locates recent reported activity; it does not date or reconstruct the complete count.
Largest 13-F holders · Q2 2026
502 filers reported a long position in ARWR for Q2 2026. 13-F holdings are filed up to 45 days after the quarter ends.
The top 10 hold
56.1%
of the 119.5M shares 13-F filers reported
Moves vs Q1 2026
4 added5 trimmed
1 not comparable
Net shares held
-5.4%
across the 9 holders with a comparable Q1 2026 book
| Rank | Holder | Value | Shares | Shares vs Q1 2026 |
|---|---|---|---|---|
| 1 | BlackRock, Inc. | $1.2B · 14.8M shares | 14.8M | -18.3% |
| 2 | Avoro Capital Advisors LLC | $925.6M · 11.4M shares | 11.4M | +6.1% |
| 3 | FMR LLC | $655.3M · 8M shares | 8M | +10.6% |
| 4 | VANGUARD PORTFOLIO MANAGEMENT LLC | $517.7M · 6.4M shares | 6.4M | -11.1% |
| 5 | VANGUARD CAPITAL MANAGEMENT LLC | $498.1M · 6.1M shares | 6.1M | +1.3% |
| 6 | STATE STREET CORP | $464.2M · 5.7M shares | 5.7M | -12.3% |
| 7 | NORGES BANK | $317.6M · 3.9M shares | 3.9M | — |
| 8 | Invesco Ltd. | $316.6M · 3.9M shares | 3.9M | +18.4% |
| 9 | GEODE CAPITAL MANAGEMENT, LLC | $298.8M · 3.5M shares | 3.5M | -17.5% |
| 10 | FRED ALGER MANAGEMENT, LLC | $269.1M · 3.3M shares | 3.3M | -1.2% |
Sign in to see each holder’s Holder IQ, factor-adjusted Holder IQ and rank, and compare these holders with all scored filers. Available on every plan.
Sign in5% holder filings (13D / 13G)
Holders of more than 5% of ARWR file with the SEC within days. A 13D holder may seek to influence the company; a 13G holder is passive. Each holder’s latest filing from the last three years.
| Filed | Holder | % of class |
|---|---|---|
| Nov 5, 2026 | FMR LLC13G · passive · amended | 6.6% |
| Aug 14, 2026 | Avoro Capital Advisors LLC13G · passive · amended | 9.64% |
| Jul 31, 2026 | VANGUARD PORTFOLIO MANAGEMENT LLC13G · passive · amended | 4.53%under 5% |
| Jul 27, 2026 | BlackRock, Inc.13G · passive · amended | 10.1% |
| Apr 29, 2026 | VANGUARD CAPITAL MANAGEMENT LLC13G · passive | 5.05% |
| Mar 26, 2026 | VANGUARD GROUP INC13G · passive · amended | 0%under 5% |
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