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Nautilus Biotechnology, Inc.

For the period ended Dec 31, 2025. Filed Feb 26, 2026.

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About this filing

A company's yearly report to the SEC, with audited financial statements. It is the fullest account a company gives of its business, its finances and the risks it sees.

FY2025 · Filed Feb 26, 2026

NAUT$2.32-2.5%Stored close · as of Nov 10, 2026

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Contents

Item 8. Consolidated Statements of Cash Flows

Nautilus Biotechnology, Inc.Consolidated Statements of Cash FlowsYears Ended December 31, 2025 and 2024

(in thousands)Year Ended December 31, 2025Year Ended December 31, 2024
Cash flows from operating activities
Net loss$(59,001)$(70,780)
Adjustments to reconcile net loss to net cash used in operating activities
Stock-based compensation6,84412,701
Amortization of operating lease right-of-use assets4,7124,378
Depreciation1,7532,059
In-process research and development—760
Amortization (accretion) of premiums (discounts) on securities, net(1,420)(2,804)
Changes in operating assets and liabilities:
Prepaid expenses and other assets544666
Accounts payable(69)(578)
Accrued expenses and other liabilities629(1,397)
Operating lease liabilities(4,688)(4,150)
Net cash used in operating activities(50,696)(59,145)
Cash flows from investing activities
Proceeds from maturities of securities108,991155,410
Purchases of securities(72,490)(86,278)
Purchases of property and equipment(1,277)(2,122)
Cash paid in connection with asset acquisition—(760)
Net cash provided by investing activities35,22466,250
Cash flows from financing activities
Proceeds from exercise of stock options58620
Proceeds from issuance of common stock under employee stock purchase plan156524
Net cash provided by financing activities2141,144
Net increase (decrease) in cash, cash equivalents and restricted cash(15,258)8,249
Cash, cash equivalents and restricted cash at beginning of period28,64820,399
Cash, cash equivalents and restricted cash at end of period$13,390$28,648
Supplementary cash flow information on non-cash activities:
Acquisitions of property and equipment included in accounts payable$99$74
Remeasurement of lease liabilities and right-of-use assets$4,228$—
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The text of this filing, as the company filed it with the SEC, without its images or exhibits. This is not investment advice.