ARGENX SE

efgartigimod

efgartigimod incorporates the ABDEG™ platform technology. We anticipate several more patient innovations to evolve

during development for which we will seek additional patent protection.

Our ARGX-109 Product Candidate

With regard to our wholly-owned ARGX-109 product candidate, we have one patent family with composition of matter

claims directed to ARGX-109. The patent family has a base expiry date in 2033. We anticipate several more patient

innovations to evolve during development for which we will seek additional patent protection. Furthermore, ARGX-109

incorporates or employs the SIMPLE ANTIBODY™ platform technology and the NHANCE™ platform technology.

empasiprubart Product Candidate

With regard to the empasiprubart product candidate, we own or have rights to multiple patent families (including one in-

licensed patent family from Broteio) with several granted patents and pending patent applications in multiple

jurisdictions in North America, South America, the EU and Asia, directed to composition of matter claims and method

of treatment claims. The in-licensed patent family from Broteio has granted patents in several countries/regions and has a

base expiry date in 2034. Additional patent families include granted patents with base expiry dates in 2039 and 2040. We

anticipate several more patient innovations to evolve during development for which we will seek additional patent

protection. empasiprubart product candidate incorporates or employs the NHANCE™ platform technology.

Our ARGX-119 Product Candidate

With regard to the ARGX-119 product candidate, we in-licensed patent families from/with NYU Langone Health, a U.S.

medical center based in New York, and additional patent families from/with the LUMC, with a U.S. granted patent and

several pending applications in multiple jurisdictions. We anticipate several more patient innovations to evolve during

development for which we will seek additional patent protection.

Our ARGX-118 Product Candidate

With regard to the ARGX-118 product candidate, we co-own a patent portfolio with VIB, an inflammation research

center in Ghent, Brussels, and Ghent University, with one U.S. granted patent and pending patent applications in

multiple jurisdictions in North America, South America, the EU and Asia. The patent family has a base expiry date in