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AGIOS PHARMACEUTICALS, INC.

For the period ended Nov 5, 2026. Filed Nov 5, 2026.

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A notice of a major event between regular reports, such as results, a deal or a change of executives. It is often the first formal record of the news.

Nov 5, 2026 · Filed Nov 5, 2026

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AGIO$29.41+4.0%Stored close · as of Nov 6, 2026
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EX-99.1 · •Operating Model Update –

Operating Model Update –

o Over the course of 2026, Agios reviewed its operating model, and will have reduced its R&D headcount by over 100 roles by year-end, representing a more than 35% decrease compared with 2025. The company expects the associated cost savings of these reductions to be realized in 2027.

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The text of this filing, as the company filed it with the SEC, without its images or exhibits. This is not investment advice.