Polaryx Therapeutics, Inc.

We have adopted a written Code of Business Conduct and Ethics that is applicable to our directors, officers and employees and is designed to deter wrongdoing and to promote:

• honest and ethical conduct;

• full, fair, accurate, timely and understandable disclosure in reports and documents that we file with the SEC and in other public communications;

• compliance with applicable laws, rules and regulations, including insider trading compliance; and

• accountability for adherence to the code and prompt internal reporting of violations of the code, including illegal or unethical behavior regarding accounting or auditing practices.

You may obtain a copy of our Code of Business Conduct and Ethics on our website atwww.polaryx.comunder Investors — Governance — Governance Documents. A copy of our Code of Business Conduct and Ethics may also be obtained without charge upon written request to Secretary, Polaryx Therapeutics, Inc., South Tower, 140 E Ridgewood Avenue, Suite 415 Paramus, NJ 07652. The Board of Directors has designated the Audit Committee to be responsible for applying and interpreting our Code of Business Conduct and Ethics in situations where questions are presented to it. We intend to disclose any amendments to the Code of Business Conduct and Ethics, or any waivers of its requirements, on our website to the extent required by applicable rules.