Erasca, Inc.

The data presented for the CN and US trials in this report are based on separate studies and include pooled and cross-study comparative data. The clinical data presented in this report comparing ERAS-0015 and other products and product candidates (including RMC-6236) are based on cross-study comparisons and are not based on anyhead-to-head clinical trials. Differences exist between trial designs, patient characteristics and other factors, and caution should be exercised in drawing any conclusions from a comparison of the data across studies as cross-study comparisons are inherently limited and such data may not be directly comparable.