VIRTUS INVESTMENT PARTNERS, INC.

Peer Companies Utilized for Comparative Financial Results

SCAN TO VIEW MATERIALS & VOTE w C/O BROADRIDGE VOTE BY INTERNET—www.proxyvote.com or from a smartphone, scan P.O. BOX 1342 the QR Barcode above. Use the Internet to transmit your voting instructions BRENTWOOD, NY 11717 and for electronic delivery of information until 11:59 p.m. Eastern Daylight Time the day before the meeting date. Follow the instructions to obtain your records and to create an electronic voting instruction form. ELECTRONIC DELIVERY OF FUTURE PROXY MATERIALS If you would like to reduce the costs incurred by our company in mailing proxy materials, you can consent to receiving all future proxy statements, proxy cards and annual reports electronically viae-mail or the Internet. To sign up for electronic delivery, please follow the instructions above to vote using the Internet and, when prompted, indicate that you agree to receive or access proxy materials electronically in future years. VOTE BYPHONE—1-800-690-6903 Use any touch-tone telephone to transmit your voting instructions until 11:59 p.m. Eastern Daylight Time the day before the meeting date. Have your proxy card in hand when you call and then follow the instructions. VOTE BY MAIL Mark, sign and date your proxy card and return it in the postage-paid envelope we have provided or return it to Vote Processing, c/o Broadridge, 51 Mercedes Way, Edgewood, NY 11717. TO VOTE, MARK BLOCKS BELOW IN BLUE OR BLACK INK AS FOLLOWS: V88726-P44457 KEEP THIS PORTION FOR YOUR RECORDS THIS PROXY CARD IS VALID ONLY WHEN SIGNED AND DATED. DETACH AND RETURN THIS PORTION ONLY VIRTUS INVESTMENT PARTNERS, INC. The Board of Directors recommends a vote FOR all the nominees listed and FOR Proposals 2 and 3. 1. Election of Directors: For Withhold 1a. George R. Aylward 1b. Peter L. Bain 1c. Paul G. Greig 1d. Timothy A. Holt 1e. Melody L. Jones 1f. W. Howard Morris 1g. John C. Weisenseel For Against Abstain 2. To ratify the appointment of Deloitte & Touche LLP to serve as our independent registered public accounting firm for the fiscal year ending ! December 31, 2026. 3. To approve, in a non-binding vote, named executive officer compensation. ! NOTE: We may also act upon such other business as may properly come before the meeting or any adjournment thereof. Please indicate if you plan to attend this meeting. Yes No Please sign exactly as your name(s) appear(s) hereon. When signing as attorney, executor, administrator, or other fiduciary, please give full title as such. Joint owners should each sign personally. All holders must sign. If a corporation or partnership, please sign in full corporate or partnership name by authorized officer. This section must be completed for your vote to be counted. Signature [PLEASE SIGN WITHIN BOX] Date Signature (Joint Owners) Date

Important Notice Regarding the Availability of Proxy Materials for the Annual Shareholder Meeting to Be Held on May 20, 2026: The Notice and Proxy Statement, Annual Report and Form 10-K are available at www.proxyvote.com. V88727-P44457 [Graphic Appears Here] Proxy — Virtus Investment Partners, Inc. One Virtus Financial Investment Plaza Partners, Inc. Hartford, Connecticut 06103 This Proxy is solicited on behalf of the Board of Directors of Virtus Investment Partners, Inc. The undersigned, revoking any previous proxies relating to these shares, hereby appoints George R. Aylward, Michael A. Angerthal, and Andra C. Purkalitis, and each of them, with power to act without the other and with power of substitution, as proxies and attorneys in-fact, and hereby authorizes them to represent and vote all the shares of Virtus Investment Partners, Inc. Common Stock that the undersigned is entitled to vote and, in their discretion, to vote upon such other business as may properly come before the 2026 Annual Meeting of Shareholders of the Company to be held Wednesday, May 20, 2026 at 9:00 a.m. Eastern Daylight Time at the offices of Virtus Investment Partners, Inc., One Financial Plaza, 19th Floor, Hartford, Connecticut, or at any adjournment or postponement thereof, with all powers that the undersigned would possess if present at the Meeting. This proxy, when properly executed, will be voted as specified herein. If no specification is made, this proxy will be voted FOR the election of each of the nominees for director listed under Proposal 1 and FOR Proposals 2 and 3. If any other matters are voted on at the Meeting, this proxy will be voted by the proxy holders on such matters in their sole discretion. (Continued and to be signed on reverse side.)