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Stoke Therapeutics, Inc.

For the period ended Dec 31, 2025. Filed Mar 16, 2026.

View on SEC.gov

About this filing

A company's yearly report to the SEC, with audited financial statements. It is the fullest account a company gives of its business, its finances and the risks it sees.

FY2025 · Filed Mar 16, 2026

STOK$27.71+4.4%Stored close · as of Nov 9, 2026

Extracted filing text, with the paragraph anchors used by the comparison.

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Item 16. Form 10-K Summary

None.

SIGNA TURES

Pursuant to the requirements of Section 13 or 15(d) of the Securities Exchange Act of 1934, as amended, the Registrant has duly caused this Annual Report on Form 10-K to be signed on its behalf by the undersigned, thereunto duly authorized.

STOKE THERAPEUTICS, INC.
Date: March 16, 2026By:/s/ Ian F. Smith
Ian F. Smith
Chief Executive Officer
(Principal Executive Officer)

POWER OF ATTORNEY

Each person whose individual signature appears below hereby authorizes and appoints Ian F. Smith and Thomas E. Leggett, and each of them, with full power of substitution and re-substitution and full power to act without the other, as his or her true and lawful attorney-in-fact and agent to act in his or her name, place and stead and to execute in the name and on behalf of each person, individually and in each capacity stated below, and to file any and all amendments to this Annual Report on Form 10-K and to file the same, with all exhibits thereto, and other documents in connection therewith, with the Securities and Exchange Commission, granting unto said attorneys-in-fact and agents, and each of them, full power and authority to do and perform each and every act and thing, ratifying and confirming all that said attorneys-in-fact and agents or any of them or their or his substitute or substitutes may lawfully do or cause to be done by virtue thereof.

Pursuant to the requirements of the Securities Exchange Act of 1934, as amended, this Annual Report on Form 10-K has been signed below by the following persons on behalf of the Registrant in the capacities and on the dates indicated.

NameTitleDate
/s/ Ian F. SmithChief Executive Officer and DirectorMarch 16, 2026
Ian F. Smith(Principal Executive Officer)
/s/ Thomas E. LeggettChief Financial OfficerMarch 16, 2026
Thomas E. Leggett(Principal Financial and Accounting Officer)
/s/ Julie A. SmithDirectorMarch 16, 2026
Julie A. Smith
/s/ Seth L. HarrisonDirectorMarch 16, 2026
Seth L. Harrison, M.D.
/s/ Adrian R. KrainerDirectorMarch 16, 2026
Adrian R. Krainer, Ph.D.
/s/ Arthur A. LevinDirectorMarch 16, 2026
Arthur A. Levin, Ph.D.
/s/ Edward M. Kaye M.D.DirectorMarch 16, 2026
Edward M. Kaye M.D
/s/ Jennifer C. BursteinDirectorMarch 16, 2026
Jennifer C. Burstein
/s/ Garry E. MenzelDirectorMarch 16, 2026
Garry E. Menzel
/s/ Arthur O. TzianabosChairman of the Board of DirectorsMarch 16, 2026
Arthur O. Tzianabos, Ph.D.

STOKE THERAPEUTICS, INC.

INDEX TO CONSOLIDATED FINANCIAL STATEMENTS

Page
Report of Independent Registered Public Accounting Firm97
Consolidated balance sheets99
Consolidated statements of operations and comprehensive loss100
Consolidated statements of stockholders’ equity101
Consolidated statements of cash flows102
Notes to consolidated financial statements103
ContentsView on SEC.gov

The text of this filing, as the company filed it with the SEC, without its images or exhibits. This is not investment advice.