STOK
Stoke Therapeutics IncNASDAQ
Healthcare • Biotechnology
Factor tilt: Small-Cap Blend
$26.54+1.80%
Close Nov 6, 2026
- Market cap
- $1.65B
- 1 month
- +10.8%
- 3 months
- -17.7%
- 1 year
- +16.3%
- 52-week range
- $22.37$38.35
- Dividend
- No dividends on record
- Short interest
- 22.5% of float10.3M shares · settled Oct 15, 2026 · -10.9% since Sep 30, 2026 · FINRA
Fundamentals · trailing 12 months to Sep 30, 2026
- Revenue
- $28.21M
- Net income
- -$243.2M
- Free cash flow
- -$180.68M
- Book value
- $352.59M
- Total debt
- —
- P/E
- —
- Price / sales
- 58.6×
- Price / book
- 4.7×
- FCF yield
- -10.9%
- Net margin
- -862.1%
EODHD (TTM) · as of Nov 6, 2026
End-of-day close from stored market data, not a live quote.
About Stoke Therapeutics Inc
Stoke Therapeutics, Inc. engages in the development of treatments for severe genetic diseases by upregulating protein expression. The company utilizes its proprietary Targeted Augmentation of Nuclear Gene Output (TANGO) approach in developing antisense oligonucleotides (ASOs) to selectively restore protein levels.
Read more
Its lead product candidates include STK-002, which is in Phase 1 clinical trials for the treatment of autosomal dominant optic atrophy; and Zorevunersen (STK-001), an investigational new medicine for the treatment of Dravet syndrome is being evaluated in phase 3 clinical trials. The company also develops programs focused on various targets, including haploinsufficiency diseases of the central nervous system and eye. It has a license and collaboration with Biogen Inc. for the development and commercialization of zorevunersen medicine for the treatment of Dravet syndrome; and Acadia Pharmaceuticals Inc. for the discovery, development, and commercialization of novel RNA-based medicines for the treatment of genetic neurodevelopmental diseases. The company was formerly known as ASOthera Pharmaceuticals, Inc. and changed its name to Stoke Therapeutics, Inc. in May 2016. Stoke Therapeutics, Inc. was incorporated in 2014 and is headquartered in Bedford, Massachusetts.
- Website
- stoketherapeutics.com
- Headquarters
- Bedford, MA, United States
- Employees
- 170
- Listed
- Jun 19, 2019
- Fiscal year ends
- December
Company profile from EODHD, stored Nov 5, 2026.
Quarterly results
The last 8 fiscal quarters as reported (EODHD). Year over year compares the same quarter a year earlier.
| Quarter | Revenue | YoY | Gross margin | Op. income | Net income |
|---|---|---|---|---|---|
| Sep 2026filed Oct 29, 2026 | $11.3M | +5.9% | 100.0% | -$77.3M | -$73.6M |
| Jun 2026filed Aug 3, 2026 | $9.3M | -32.5% | 87.8% | -$65.4M | -$61.6M |
| Mar 2026filed May 7, 2026 | $6.2M | — | 83.2% | -$53.4M | -$50.0M |
| Dec 2025filed Mar 16, 2026 | $1.4M | -93.8% | 24.8% | -$61.4M | -$57.9M |
| Sep 2025filed Nov 4, 2025 | $10.6M | +117.2% | 90.7% | -$43.1M | -$38.3M |
| Jun 2025filed Aug 12, 2025 | $13.8M | +186.0% | — | -$27.3M | -$23.5M |
| Mar 2025filed May 13, 2025 | — | — | — | — | — |
| Dec 2024filed Mar 18, 2025 | $22.6M | +707.1% | — | -$13.7M | -$10.5M |
Short-interest history
FINRA reports open short positions for a settlement date. The publication date is later. These are reported positions, with a separate date for each observation.
Compare the reported short exposure around the dates you bought, sold or watched STOK. A long position benefits from price rises; a short position benefits from falls. A change in these counts does not predict either move.
Settlement Oct 15, 2026
10,256,830 shares short
-1,248,580 shares (-10.9%) vs Sep 30, 2026
22.5% of the stored float. Published Oct 26, 2026.
Settlement Sep 30, 2026
11,505,410 shares short
+355,174 shares (+3.2%) vs Sep 15, 2026
23.4% of the stored float. Published Oct 9, 2026.
Settlement Sep 15, 2026
11,150,236 shares short
-53,191 shares (-0.5%) vs Aug 31, 2026
23.8% of the stored float. Published Sep 24, 2026.
Settlement Aug 31, 2026
11,203,427 shares short
-1,774,675 shares (-13.7%) vs Aug 14, 2026
24% of the stored float. Published Sep 10, 2026.
Settlement Aug 14, 2026
12,978,102 shares short
-2,831,585 shares (-17.9%) vs Jul 31, 2026
27.8% of the stored float. Published Aug 25, 2026.
Settlement Jul 31, 2026
15,809,687 shares short
+117,077 shares (+0.7%) vs Jul 15, 2026
33.8% of the stored float. Published Aug 11, 2026.
Change = this settlement’s shares short − the previous recorded settlement’s shares short; percentage change divides by that earlier count. A zero earlier count has no percentage change. Split-spanning counts are left uncompared. Float percentages use the stored settlement observation, not today’s float.
Source: stored FINRA equity short-interest records, up to six settlements from the last 240 days. FINRA data and reporting dates · How to read short interest
Dividends and stock splits
See the recorded cash amounts and dates behind STOK’s income, and the splits that change its share count. Dates below are stored event records, not confirmation of a payment to your account.
Cash-dividend records
No qualified cash-dividend records are stored. This does not establish that the company pays no dividend.
Up to six Polygon cash-dividend events, including recorded ex-dates within the next 120 days. Amounts retain their recorded currency and decimal precision. Historical amounts are not restated to a common split basis, annualized, or converted to dollars.
For a long holding, compare the ex-date with when you held the shares and check the pay date against your broker’s cash history. Owning the stock today does not establish past entitlement. For a short holding, a dividend can create a payment obligation to the share lender.
Ex-dates and special dividend rules · Short-sale dividend obligations · Dividend data definitions
Split history
1 for 9 · reverse split
Effective Jun 6, 2019
Each 9 pre-split shares become 1 post-split share.
Source: EODHD
Up to six stored split dates through Nov 7, 2026. Equivalent vendor ratios are combined; conflicting ratios are left out. This history may be incomplete.
A split changes the share count and per-share price basis; it does not by itself add investment value. Put your holding’s earlier and later share counts on the same basis before comparing them. This applies to both long shares and shares owed on a short position.
How stock splits workPortfolio context
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Smart money context
Holder IQ: MEDIUM
38 smart-money holders: institutions with a high Holder IQ
Q2 2026, filed Sep 22, 2026
Smart-money 13F trend: distributing (light)
Unlock crowding heatmapUnlock filer discoveryInsider context
Sentiment: bearish
Last trade: sell 3 days ago
Read the insider context evidence
What it means for you
Sign in to read your holdings or watchlist context. No personal position or direction is inferred.
What happened
Stored recent-activity label: bearish. This context label is separate from the scored insider signal read.
Why it can matter
A count of reported activity describes a sample, not purchase conviction, an insider’s intent or a future price move. Neutral is not an all-clear, and absent direction is not neutral evidence.
How we got this
The current context rule reads at most 50 nonduplicate issuer/share-class records filed in the last 90 days. It counts a bullish direction or purchase code P toward bullish, and a bearish direction or sale code S toward bearish. A side must exceed the opposite count by more than two to set its label; otherwise nonzero directional counts produce neutral. Calculation unavailable for this saved label: its counts, exact records, as-of time and rule version are not supplied here. Do not substitute the separate scored read’s different window or denominator.
Where the data comes from
Stored SEC Forms 3/4/5 insider-signal records, ordered by filing date with amendment duplicates excluded. Filing date is not transaction date. The last-trade line locates recent reported activity; it does not date or reconstruct the complete count.
Red flags: 0
Read the insider context evidence
What it means for you
Sign in to read your holdings or watchlist context. No personal position or direction is inferred.
What happened
Stored recent-activity label: bearish. This context label is separate from the scored insider signal read.
Why it can matter
A count of reported activity describes a sample, not purchase conviction, an insider’s intent or a future price move. Neutral is not an all-clear, and absent direction is not neutral evidence.
How we got this
The current context rule reads at most 50 nonduplicate issuer/share-class records filed in the last 90 days. It counts a bullish direction or purchase code P toward bullish, and a bearish direction or sale code S toward bearish. A side must exceed the opposite count by more than two to set its label; otherwise nonzero directional counts produce neutral. Calculation unavailable for this saved label: its counts, exact records, as-of time and rule version are not supplied here. Do not substitute the separate scored read’s different window or denominator.
Where the data comes from
Stored SEC Forms 3/4/5 insider-signal records, ordered by filing date with amendment duplicates excluded. Filing date is not transaction date. The last-trade line locates recent reported activity; it does not date or reconstruct the complete count.
Largest 13-F holders · Q2 2026
198 filers reported a long position in STOK for Q2 2026. 13-F holdings are filed up to 45 days after the quarter ends.
The top 10 hold
53.9%
of the 76.2M shares 13-F filers reported
Moves vs Q1 2026
4 added3 trimmed
3 unchanged
Net shares held
+1.2%
across the 10 holders with a comparable Q1 2026 book
| Rank | Holder | Value | Shares | Shares vs Q1 2026 |
|---|---|---|---|---|
| 1 | BlackRock, Inc. | $192.3M · 5.9M shares | 5.9M | +9.1% |
| 2 | RTW INVESTMENTS, LP | $184M · 5.6M shares | 5.6M | Unchanged |
| 3 | FMR LLC | $173.8M · 5.3M shares | 5.3M | -1.3% |
| 4 | Lynx1 Capital Management LP | $132.1M · 4M shares | 4M | -15.2% |
| 5 | Redmile Group, LLC | $129.1M · 3.9M shares | 3.9M | -5.2% |
| 6 | WELLINGTON MANAGEMENT GROUP LLP | $115.2M · 3.5M shares | 3.5M | +13.7% |
| 7 | MORGAN STANLEY | $113M · 3.5M shares | 3.5M | +0.9% |
| 8 | BAKER BROS. ADVISORS LP | $109.2M · 3.3M shares | 3.3M | Unchanged |
| 9 | TORONTO DOMINION BANK | $103.8M · 3.2M shares | 3.2M | Unchanged |
| 10 | STATE STREET CORP | $93.3M · 2.9M shares | 2.9M | +25.3% |
Sign in to see each holder’s Holder IQ, factor-adjusted Holder IQ and rank, and compare these holders with all scored filers. Available on every plan.
Sign in5% holder filings (13D / 13G)
Holders of more than 5% of STOK file with the SEC within days. A 13D holder may seek to influence the company; a 13G holder is passive. Each holder’s latest filing from the last three years.
| Filed | Holder | % of class |
|---|---|---|
| Nov 5, 2026 | FMR LLC13G · passive · amended | 7.5% |
| Sep 30, 2026 | BIOTECHNOLOGY VALUE FUND L P13G · passive | 5.6% |
| Aug 14, 2026 | Lynx1 Capital Management LP13G · passive · amended | 6.5% |
| Aug 12, 2026 | TORONTO DOMINION BANK13G · passive · amended | 4.9%under 5% |
| May 15, 2026 | RTW INVESTMENTS, LP13G · passive · amended | 9.9% |
| May 15, 2026 | Redmile Group, LLC13G · passive · amended | 6.7% |
| May 15, 2026 | WELLINGTON MANAGEMENT GROUP LLP13G · passive | 5.2% |
| Mar 27, 2026 | VANGUARD GROUP INC13G · passive · amended | 0%under 5% |
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