Skip to main content

Silexion Therapeutics Corp

For the period ended Oct 5, 2026. Filed Oct 5, 2026.

View on SEC.gov

About this filing

What shareholders are asked to vote on at a company's meeting. It is where to find what directors and top executives are paid, and who owns the most shares.

Oct 5, 2026 · Filed Oct 5, 2026

Use the contents to explore the available documents and sections.

SLXN$0.15+1.0%Stored close · as of Nov 6, 2026
See the whole filing, with its images and exhibits

Cover page

Show cover page

DEF 14A 1 zk2636195.htm DEF 14A

UNITED STATES

SECURITIES AND EXCHANGE COMMISSION

Washington, D.C. 20549

SCHEDULE 14A

Proxy Statement Pursuant to Section 14(a) of the

Securities Exchange Act of 1934

Filed by the Registrant ☒

Filed by a Party other than the Registrant ☐

Check the appropriate box:

☐Preliminary Proxy Statement
☐Confidential, for Use of the Commission Only (as permitted by Rule 14a-6(e)(2))
☒Definitive Proxy Statement
☐Definitive Additional Materials
☐Soliciting Material under §240.14a-12

SILEXION THERAPEUTICS CORP

(Name of Registrant as Specified In Its Charter)

(Name of Person(s) Filing Proxy Statement, if other than the Registrant)

Payment of Filing Fee (Check the appropriate box):

☒No fee required.
☐Fee paid previously with preliminary materials.
☐Fee computed on table in exhibit required by Item 25(b) per Exchange Act Rules 14a-6(i)(1) and 0-11.

Silexion Therapeutics Corp

+972-3-7564999

October 5, 2026

Dear Shareholder:

You are cordially invited to attend an extraordinary general meeting (the “extraordinary general meeting” or “meeting”) of Silexion Therapeutics Corp (“Silexion”, the “Company”, “our company”, “we” or “us”), which will be held at 9:00 a.m., Eastern time/ 4:00 p.m. local (Israel) time, on Monday, October 19, 2026 at the offices of our external legal counsel, Meitar Law Offices, 1 Ariel Sharon Street, 36 th Floor, Givatayim, Israel 5320046. The extraordinary general meeting may also be attended virtually over the internet. You will be able to attend, and submit your questions during (but not speak at or vote at), the extraordinary general meeting online by visitinghttps://www.cstproxy.com/silexion/fifthegm2026, or by calling 1-800-450-7155 (toll-free, within the U.S. and Canada) or +1 857-999-9155 (outside of the U.S. and Canada, standard rates apply), conference ID 7672835#.

At the extraordinary general meeting, we will present for your approval two proposals:

**Proposal 1 - Authorized Share Capital Increase Proposal:**An increase to the authorized share capital of the Company by 500,000,000 ordinary shares, from US$2,146,500 divided into 15,900,000 ordinary shares of a par value of US$0.135 each (which is our current authorized share capital), to US$69,646,500, divided into 515,900,000 ordinary shares of a par value of US$0.135 each.

Proposal 2 -Reverse Share Split Proposal: A proposal to allow the Company’s board of directors (the “Board of Directors”) to effect a reverse share split of the Company’s ordinary shares, par value $0.135 per share, at a ratio of not less than 1-for-15 and not more than 1-for-25, with the exact ratio to be determined by the Board of Directors prior to the extraordinary general meeting and to be presented for approval by our shareholders at the meeting.

We refer to the foregoing proposals as the “Authorized Share Capital Increase Proposal” and the “Reverse Share Split Proposal”, respectively. Under the laws of the Cayman Islands and, in the case of the Authorized Share Capital Increase Proposal and the Reverse Share Split Proposal, Articles 17.1.1 and 17.1.4, respectively, of our Amended and Restated Articles of Association, an ordinary resolution adopted by a majority of our shareholders as, being entitled to do so, vote in person or by proxy at the extraordinary general meeting (including a unanimous written resolution) is needed for approval of each proposal. Abstentions will have no effect on the outcome of the vote on any proposal under Cayman Islands law.

The Authorized Share Capital Increase Proposal is intended to support our ability to regain and maintain compliance with Nasdaq Listing Rule 5550(b)(1), which requires that our company have at least $2.5 million of shareholders’ equity under the Equity Standard of the Nasdaq Capital Market, on which our ordinary shares and warrants are listed. Our financing activities and Nasdaq listing compliance are dependent on an ample supply of authorized share capital, which has been depleted over time due to a combination of frequent financing transactions and difficult market conditions adversely impacting the price of our ordinary shares. Our Nasdaq listing is a critical asset of our company and our shareholders, as it enhances the price and liquidity of, and the trading market for, our securities, and it is therefore in the best interest of our shareholders that we preserve it.

Beyond the purpose of maintaining our Nasdaq listing, we require increased share capital for the basic financing needs of our operations and potential business development transactions, in keeping with our goal of creating substantive value for our shareholders. As we advance our Phase 2/3 clinical trials for SIL204, our expenses are expected to increase substantially, and we will need both sufficient funding and transactional flexibility for that development process. An enhanced authorized share capital will provide us with that requisite flexibility to conduct financings and to explore potential business development transactions, which can help us to advance our product candidates.

Under our current authorized share capital, we have US$2,146,500 divided into 15,900,000 ordinary shares of a par value of US$0.135 each, of which 14,473,292 ordinary shares were outstanding as of September 30, 2026. We expect to issue additional ordinary shares or ordinary share equivalents under our financing arrangements and other commitments, including our at-the-market (ATM) offering program, outstanding warrants, and potential public offerings. The proposed increase to our authorized share capital by 500 million ordinary shares (as will be adjusted downwards based on the ratio of the proposed reverse share split) represents the minimum increase that is expected to be needed to enable us to maintain Nasdaq listing compliance while continuing to progress with our clinical program and potential complementary business development opportunities for the creation of shareholder value, for the near-to-mid-term period.

The Reverse Share Split Proposal is intended to enable us to restore our compliance with Nasdaq Listing Rule 5550(a)(2), which requires that our ordinary shares maintain a minimum bid price of $1.00 per share on an ongoing basis in order to remain listed on the Nasdaq Capital Market. Because we effected a 1-for-10 reverse share split on May 28, 2026, and our share price has recently closed below $1.00 for 30 consecutive trading days, of which we received notice from the Nasdaq Listing Qualifications Department on September 25, 2026, we would ordinarily be subject to immediate delisting proceedings. However, we have noted to the Nasdaq hearings panel where we appeared on September 24, 2026 that we expect the proposed reverse share split to enable us to restore compliance with the minimum bid price requirement as soon as practicable after the meeting, assuming that our shareholders approve the Reverse Share Split Proposal, and the hearings panel is considering our compliance plan in determining whether to allow us to remain listed on Nasdaq. Depending on market conditions and the market price of the ordinary shares immediately prior to the extraordinary general meeting, our Board of Directors will determine which resolution— containing a specific reverse split ratio – will be presented at the meeting. To the extent each of the Authorized Share Capital Increase Proposal and the Reverse Share Split Proposal is approved at the meeting, the number of shares by which our authorized share capital will be enlarged pursuant to the Authorized Share Capital Increase Proposal will be lessened, and the par value of those additional authorized shares will be increased, in proportion to the ratio of the Reverse Share Split Proposal (once it is implemented).

The formal notice of, and the proxy statement for, the extraordinary general meeting accompany this letter.

Whether or not you plan to attend the extraordinary general meeting, it is important that your shares be represented and voted at the meeting. After reading the attached formal notice and proxy statement, please promptly vote. If you are a shareholder of record, you can vote by completing and returning the enclosed proxy card or by going online towww.cstproxyvote.com and utilizing the control number appearing on your proxy card to vote. If you hold your shares in “street name” through a bank, broker or other nominee, you can provide voting instructions to your bank, broker or other nominee to ensure that your shares are represented and voted at the extraordinary general meeting, either via the enclosed voting instruction form or online- atwww.proxyvote.com-- as described in the enclosed instructions.

If you have any questions or need assistance voting your ordinary shares, please contact Mirit Horenshtein Hadar, our Chief Financial Officer and Secretary, by calling +972-3-756-4999, or by emailing mirit@silexion.com.

Thank you for your participation. We look forward to your continued support. Sincerely, /s/ Ilan Hadar Chairman of the Board and Chief Executive Officer

  • ii -

Silexion Therapeutics Corp

+972-3-756-4999

NOTICE OF EXTRAORDINARY GENERAL MEETING

OF SILEXION THERAPEUTICS CORP (“SILEXION” OR THE “COMPANY”)

Time and Date of Extraordinary General Meeting (the “meeting”)9:00 a.m. Eastern Daylight Time/4:00 p.m. local (Israel) time on Monday, October 19, 2026
Place of Meeting (in-person attendance)Meitar Law Offices 1 Ariel Sharon Street, 36th Floor Givatayim, Israel 5320046
(virtual or telephonic attendance- may submit questions, but not vote)https://www.cstproxy.com/silexion/fifthegm2026. Log into the virtual site by using the control number included in your proxy materials; or call 1 800-450-7155 (toll-free, within the U.S. and Canada) or +1 857-999-9155 (outside of the U.S. and Canada- standard rates apply), conference ID: 7672835#.
Agenda Items(1) Proposal 1 - Authorized Share Capital Increase Proposal (the “Authorized Share Capital Increase Proposal”): An increase to the Company’s authorized share capital under paragraph 5 of the Company’s Amended and Restated Memorandum of Association by 500,000,000 of the Company’s ordinary shares (“ordinary shares”), from US$2,146,500, divided into 15,900,000 ordinary shares of a par value of US$0.135 each (which is the Company’s current authorized share capital), to US$69,646,500, divided into 515,900,000 ordinary shares of a par value of US$0.135 each. (2) Proposal 2- Reverse Share Split Proposal (the “Reverse Share Split Proposal”): A proposal to allow the Company’s board of directors (the “Board” or “Board of Directors”) to effect a reverse share split of the Company’s ordinary shares, par value $0.135 per share, at a ratio of not less than 1-for-15 and not more than 1-for-25, with the exact ratio to be determined by the Board prior to the meeting and to be presented for approval by our shareholders at the meeting.
Required Majority for Approval of ProposalsUnder the laws of the Cayman Islands and, in the case of the Authorized Share Capital Increase Proposal and the Reverse Share Split Proposal, Articles 17.1.1 and 17.1.4, respectively, of Silexion’s Amended and Restated Articles of Association, the approval of each of the proposals requires an ordinary resolution, adopted by the affirmative vote of shareholders holding ordinary shares amounting in the aggregate to at least a majority of the votes cast by shareholders as, being entitled to do so, vote in person or by proxy at the meeting with respect to such proposal. Abstentions and broker non-votes are not considered “actually cast” and are therefore not taken into consideration in determining whether a majority has been achieved for either proposal.
Purpose of Agenda ItemsAuthorized Share Capital Increase Proposal: The primary purpose of the Authorized Share Capital Increase Proposal is to enable the Company to restore and maintain compliance with Nasdaq Listing Rule 5550(b)(1), which requires that the Company have at least $2.5 million of shareholders’ equity on a continued basis under the Equity Standard of the Nasdaq Capital Market, on which the Company’s ordinary shares and warrants are listed. Beyond the need to comply with the Nasdaq shareholders’ equity requirement, the Company requires an enhanced authorized share capital to pursue its ongoing operational needs related to its clinical development of RNA interference (RNAi) therapies, including financing activities, and potential business development opportunities for complementary assets. The Company intends to manage its enlarged authorized share capital to reinforce, as much as possible, the price and liquidity of, and the trading market for, its traded securities. The proposed increase of 500,000,000 authorized ordinary shares (subject to adjustment if the Reverse Share Split Proposal is approved) is currently expected to be sufficient for the Company to maintain its requisite shareholders’ equity level and achieve the foregoing additional objectives in the short term to mid term. Reverse Share Split Proposal: The purpose of the proposed reverse share split is to enable the Company to restore its compliance with Nasdaq Listing Rule 5550(a)(2), which requires that the ordinary shares maintain a minimum bid price of $1.00 per share on an ongoing basis in order to remain listed on the Nasdaq Capital Market. The market price of our ordinary shares has fallen out of compliance with that bid price requirement for a consecutive 30 trading day period, of which we received notice from the Nasdaq Listing Qualifications Department on September 25, 2026, and our ordinary shares would ordinarily have been subject to immediate delisting proceedings. However, we noted to the Nasdaq hearings panel where we appeared on September 24, 2026 that we expect the proposed reverse share split to enable us to restore compliance with the minimum bid price requirement as soon as practicable after the meeting, assuming that our shareholders approve the Reverse Share Split Proposal, and the hearings panel is considering our compliance plan in determining whether to allow us to remain listed on Nasdaq. Based on market conditions and the market price of our ordinary shares immediately prior to the meeting, our Board of Directors will determine the exact reverse split ratio to be presented at the meeting.
Board RecommendationThe Board recommends a vote “FOR” each of the Authorized Share Capital Increase Proposal and the Reverse Share Split Proposal.
Record DateYou are entitled to notice of, and to vote at, the meeting if you held an ordinary share of Silexion as of the close of business on Tuesday, September 29, 2026.

ii

Additional Proxy MaterialsThe Authorized Share Capital Increase Proposal and the Reverse Share Split Proposal and details with respect to the meeting, are described more fully in the attached proxy statement, which we are sending (together with this notice and a proxy card or voting instruction form) to our shareholders and which we urge you to read in its entirety. Copies of this notice, the attached proxy statement and the related proxy card are also being filed with the U.S. Securities and Exchange Commission (the “SEC”) under cover of Schedule 14A, which documents may be obtained for free from the SEC’s website at www.sec.gov, the “Investors” portion of our website, www.silexion.com, or at the website for the meeting, https://www.cstproxy.com/silexion/fifthegm2026
Quorum RequirementNo action may be taken at the meeting unless a quorum, consisting of the holders of at least a majority of the Company’s outstanding ordinary shares, are present in person or by proxy. If a quorum is not present at the meeting within half an hour from the time designated for the meeting to begin, the chairman of the meeting will adjourn the meeting for one week, to Monday, October 26, 2026, at the same time and same place at which the meeting is held, at which time resolutions may be adopted solely with respect to the proposals described in this notice of the original meeting. If a quorum is not present at the reconvened meeting within half an hour from the time designated for it to begin, those shareholders present (regardless of how many) will be deemed to constitute a quorum and action may be taken on the matters on the agenda.
Required VoteApproval of each of the Authorized Share Capital Increase Proposal and the Reverse Share Split Proposal requires the affirmative vote of shareholders holding ordinary shares amounting in the aggregate to at least a majority of the votes cast by shareholders as, being entitled to do so, vote in person or by proxy at the meeting with respect to such proposal. Abstentions and broker non-votes are not considered “actually cast” and are therefore not taken into consideration in determining whether a majority has been achieved for any proposal, but the ordinary shares represented thereby are considered present for purposes of the quorum requirement.
Means of VotingThe vote of each of the Company’s shareholders is important regardless of whether or not any particular shareholder attends the meeting. Accordingly, we urge you to read the attached proxy statement and vote your ordinary shares promptly, regardless of the number of ordinary shares you own. You may vote the ordinary shares that you own directly (i.e., as a record shareholder) via proxy, by signing and returning the form of proxy in the enclosed envelope. If you prefer to vote via the internet, you may do so at www.cstproxyvote.com, by using the control number that appears towards the bottom of the physical proxy card that was sent to you. You may revoke your proxy at any time before it is voted, and you may attend the meeting and vote in person even if you have previously signed a proxy or voted via the internet. As an alternative to voting via proxy or via the internet, you may vote the ordinary shares that you own directly in person by attending the meeting. If your ordinary shares are held in street name on Nasdaq (i.e., ordinary shares that are held through a bank, broker or other nominee), you may instruct the nominee as to how you want your ordinary shares voted, including via the internet (at www.proxyvote.com). Specific instructions as to how to vote are set forth on the enclosed voting instruction form provided by your bank, broker, or nominee. If voting via proxy, your vote must be received by 11:59 p.m., Eastern time on Sunday, October 18, 2026 in order to be counted towards the tally of votes on the proposals at the meeting. If submitting voting instructions via a voting instruction form or via the internet, the deadline for receipt of your voting instructions will be at such time on such date as may be indicated in the voting directions provided to you.

iii

Attendance at Meeting (in person)If you are a shareholder holding ordinary shares as of the record date for the meeting (Tuesday, September 29, 2026) and desire to attend the meeting in person, if a record shareholder, please provide at the meeting the name under which your ordinary shares are held of record and proof of ownership (a copy of your share certificate or a statement showing book-entry shares). If you hold your ordinary shares in “street name” (through a bank or broker), please bring to the meeting the required proof of ownership described for attendance at the meeting, namely: a “legal proxy” from the broker, trustee or nominee that holds your shares, giving you the right to vote the shares at the meeting, along with an account statement or other proof that shows that you owned your shares as of the record date for the meeting.
(virtual or telephonic attendance)https://www.cstproxy.com/silexion/fifthegm2026. Log into the virtual site by using the control number included in your proxy materials, or call 1 800-450-7155 (toll-free, within the U.S. and Canada) or +1 857-999-9155 (outside of the U.S. and Canada- standard rates apply), conference ID: 7672835#. You may submit questions, but not vote, while attending the meeting virtually or telephonically.

By Order of the Board of Directors,

/s/ Ilan Hadar

Chairman of the Board and Chief Executive Officer October 5, 2026

This Notice of Extraordinary General Meeting was

first published by the Company on October 5, 2026.

Important Notice Regarding the Availability of Proxy Materials for the extraordinary general meeting

of Silexion to be held on October 19, 2026:

This notice and the accompanying proxy statement are available free of charge at the “Investors”

portion of the Company’s website, www.silexion.com, and at

https://www.cstproxy.com/silexion/fifthegm2026.

iv

Page
INFORMATION CONCERNING ATTENDANCE AND VOTING1
QUESTIONS AND ANSWERS ABOUT THE PROXY MATERIALS AND THE EXTRAORDINARY GENERAL MEETING1
PROPOSAL 1 - AUTHORIZED SHARE CAPITAL INCREASE PROPOSAL8
PROPOSAL 2 - REVERSE SHARE SPLIT PROPOSAL11
RISK FACTORS RELATED TO THE PROPOSALS18
SECURITY OWNERSHIP OF CERTAIN BENEFICIAL OWNERS AND MANAGEMENT20
OTHER MATTERS22

Silexion Therapeutics Corp

+972-3-7564999

PROXY STATEMENT

FOR EXTRAORDINARY GENERAL MEETING

ContentsView on SEC.gov

The text of this filing, as the company filed it with the SEC, without its images or exhibits. This is not investment advice.