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Xenon Pharmaceuticals Inc

For the period ended Dec 31, 2024. Filed Feb 27, 2025.

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A company's yearly report to the SEC, with audited financial statements. It is the fullest account a company gives of its business, its finances and the risks it sees.

FY2024 · Filed Feb 27, 2025

XENE$41.39+2.3%Stored close · as of Nov 10, 2026

Extracted filing text, with the paragraph anchors used by the comparison.

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Contents

Item 15. Exhibits, Financial Statement Schedules

(a)(1) Financial Statements — The financial statements included in Item 8 are filed as part of this Annual Report on Form 10-K.

(a)(2) Financial Statement Schedules — All schedules have been omitted because they are not applicable or required, or the information required to be set forth therein is included in the consolidated Financial Statements or notes thereto included in Item 8 of this Annual Report on Form 10-K.

(a)(3) Exhibits — The exhibits required by Item 601 of Regulation S-K are listed in paragraph (b) below.

(b) Exhibits — The exhibits listed in the table below are filed herewith or are incorporated by reference to exhibits previously filed with the SEC.

ExhibitNumber · Description of Document · Incorporated by Reference
Form · File No. · Exhibit · Filing Date
3.1Articles of the Company.10-Q001-366873.1December 15, 2014
3.1AArticles of Amendment to the Articles of the Company, creating the Series 1 Preferred Shares.8-K001-366873.1March 28, 2018
3.2Amended and Restated By-laws of the Company.10-Q001-366873.2December 15, 2014
4.1Form of Common Share Certificate.S-1/A333-1986664.1October 6, 2014
4.2Warrant to Purchase Shares, dated August 3, 2018, by and between Xenon Pharmaceuticals Inc. and Silicon Valley Bank.8-K001-366874.1August 7, 2018
4.3Description of Securities.
4.4Form of Pre-Funded Warrant.8-K001-366874.1October 6, 2021
4.5Form of Pre-Funded Warrant.8-K001-366874.1June 23, 2022
4.6Form of Pre-Funded Warrant.8-K001-366874.1November 30, 2023
10.1#Stock Option Plan, as amended, and form of option agreement thereunder.S-1/A333-19866610.7October 6, 2014
10.2#Amended and Restated 2014 Equity Incentive Plan and form of share option agreement used thereunder.8-K001-3668710.1June 2, 2022
10.3#Amended and Restated 2014 Equity Incentive Plan and form of share option agreement used thereunder.8-K001-3668710.1June 5, 2024
10.4#Form of Director and Executive Officer Indemnification Agreement.S-1/A333-19866610.15October 6, 2014
10.5†Asset Purchase Agreement, dated April 25, 2017, by and between the Company and 1st Order Pharmaceuticals, Inc.10-Q001-3668710.2August 3, 2017
10.6Milestone and Royalty Buy-Out Agreement, dated September 7, 2018, by and among Xenon Pharmaceuticals Inc., Valeant Pharmaceuticals Ireland Limited and Valeant Pharmaceuticals Luxembourg S.a.r.l.8-K001-3668710.1September 11, 2018
10.7#Amended and Restated Employment Agreement, dated March 19, 2019, by and between the Company and Robin Sherrington.10-K001-3668710.1March 9, 2020
10.8#Employment Agreement, dated July 14, 2020, by and between the Company and Christopher Von Seggern.10-Q001-3668710.3November 5, 2020
10.9#Employment Agreement, dated January 13, 2021, by and between the Company and Ian Mortimer.8-K001-3668710.2January 14, 2021
ExhibitNumber · Description of Document · Incorporated by Reference
Form · File No. · Exhibit · Filing Date
10.10#Employment Agreement, dated January 13, 2021, by and between the Company and Sherry Aulin.8-K001-3668710.4January 14, 2021
10.11#Employment Agreement, dated August 18, 2021, by and between the Company and Christopher Kenney.10-Q001-3668710.3November 10, 2021
10.12#2019 Inducement Equity Incentive Plan and related form of share option agreement.8-K001-3668710.1September 10, 2019
10.13††License and Collaboration Agreement, dated as of December 2, 2019, by and between Xenon Pharmaceuticals Inc. and Neurocrine Biosciences, Inc.8-K001-3668710.1December 2, 2019
10.14Share Purchase Agreement, dated as of December 2, 2019, by and between Xenon Pharmaceuticals Inc. and Neurocrine Biosciences, Inc.8-K001-3668710.2December 2, 2019
10.15††Amendment No. 1 to Asset Purchase Agreement, dated August 4, 2020, by and between the Company and 1st Order Pharmaceuticals Inc.10-Q001-3668710.2August 6, 2020
10.16At-the-Market Equity Offering Sales Agreement dated as of August 6, 2020, by and among Xenon Pharmaceuticals Inc., Jefferies LLC and Stifel, Nicolaus & Company, Incorporated.8-K001-366871.1August 6, 2020
10.17Amendment No. 1 to the At-the-Market Equity Offering Sales Agreement, dated March 1, 2022, by and among Xenon Pharmaceuticals Inc., Jefferies LLC and Stifel, Nicolaus & Company, Incorporated.8-K001-366871.1March 1, 2022
10.18††Amendment #1, dated January 13, 2021, to the License and Collaboration Agreement, dated December 2, 2019, by and between Xenon Pharmaceuticals Inc. and Neurocrine Biosciences, Inc.8-K001-3668710.1January 14, 2021
10.19Share Purchase Agreement, dated as of September 8, 2021, by and between Xenon Pharmaceuticals Inc. and Neurocrine Biosciences, Inc.8-K001-3668710.1September 8, 2021
10.20Lease Agreement, effective November 24, 2021, by and between the Company and Redstone Enterprises Ltd.8-K001-3668710.1December 1, 2021
10.21Share Purchase Agreement, dated as of January 11, 2022, by and between Xenon Pharmaceuticals Inc. and Neurocrine Biosciences, Inc.8-K001-3668710.1January 12, 2022
10.22††Amendment #2, dated February 25, 2022, to the License and Collaboration Agreement, dated December 2, 2019, by and between Xenon Pharmaceuticals Inc. and Neurocrine Biosciences, Inc.10-K001-3668710.30March 1, 2022
10.23††Consent to Alterations and Lease Modification Agreement between Redstone Enterprises Ltd. and Xenon Pharmaceuticals Inc., effective May 19, 2022.10-Q001-3668710.1August 9, 2022
10.24#Employment Agreement, dated November 4, 2022, by and between the Company and Andrea DiFabio.10-Q001-3668710.1November 8, 2022
10.25#Executive Incentive Compensation Plan.8-K001-3668710.1March 14, 2023
10.26Consent to Alterations Agreement between Redstone Enterprises Ltd. and Xenon Pharmaceuticals Inc., effective March 27, 2023.10-Q001-3668710.1August 9, 2023
ExhibitNumber · Description of Document · Incorporated by Reference
Form · File No. · Exhibit · Filing Date
10.27Consent to Alterations Agreement between Redstone Enterprises Ltd. and Xenon Pharmaceuticals Inc., effective August 16, 2023.10-K001-3668710.27February 29, 2024
10.28#Employment Agreement, dated December 15, 2023, by and between the Company and James Empfield.10-K001-3668710.28February 29, 2024
10.29Form of Performance Share Award Agreement10-Q001-3668710.1May 9, 2024
10.30#Letter Agreement, dated January 15, 2025, by and between the Company and Christopher Von Seggern.
10.31#Consulting Agreement, dated January 17, 2025, by and between the Company and Christopher Von Seggern.
10.32#2025 Inducement Equity Incentive Plan and related form agreements.
10.33#Post-Employment Consulting Agreement, dated February 27, 2025, by and between the Company and Sherry Aulin.
19Insider Trading Policy.
21.1List of Subsidiaries of the Company.10-K001-3668721.1March 8, 2017
23.1Consent of KPMG LLP, Independent Registered Public Accounting Firm.
24.1Powers of Attorney (contained on signature page).
31.1Rule 13a-14(a) / 15d-14(a) Certification of Principal Executive Officer
31.2Rule 13a-14(a) / 15d-14(a) Certification of Principal Financial Officer
32.1*Section 1350 Certification of Principal Executive Officer
32.2*Section 1350 Certification of Principal Financial Officer
97Clawback Policy, effective as of October 2, 2023.10-K001-3668797February 29, 2024
101.INSInline XBRL Instance Document – the instance document does not appear in the Interactive Data File because XBRL tags are embedded within the Inline XBRL document
101.SCHInline XBRL Taxonomy Extension Schema Document with Embedded Linkbases Document
104Cover Page Interactive Data File (embedded within the Inline XBRL document)

† Confidential treatment has been granted with respect to certain portions of this exhibit. Omitted portions have been filed separately with the Securities and Exchange Commission.

†† Portions of this exhibit have been omitted in accordance with Item 601(b)(10) of Regulation S-K because they are private, confidential and not material.

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