XENE
Xenon Pharmaceuticals IncNASDAQ
Healthcare • Biotechnology
Factor tilt: Mid-Cap Blend
$39.17+3.95%
Close Nov 6, 2026
- Market cap
- $3.79B
- 1 month
- +8.3%
- 3 months
- -39.0%
- 1 year
- +1.3%
- 52-week range
- $33.49$70.96
- Dividend
- No dividends on record
- Next-quarter EPS estimate
- -$1.14Quarter to Sep 30, 2026 · 11 analysts · +0.5% in 30d
- Short interest
- 8.1% of float7.3M shares · settled Oct 15, 2026 · +21.6% since Sep 30, 2026 · FINRA
Fundamentals · trailing 12 months to Jun 30, 2026
- Revenue
- —
- Net income
- -$409.2M
- Free cash flow
- -$338.53M
- Book value
- $1.24B
- Total debt
- $6.42M
- P/E
- —
- Price / sales
- —
- Price / book
- 3×
- FCF yield
- -8.9%
- Net margin
- —
EODHD (TTM) · as of Nov 6, 2026
End-of-day close from stored market data, not a live quote.
About Xenon Pharmaceuticals Inc
Xenon Pharmaceuticals Inc., a neuroscience-focused biopharmaceutical company, engages in the discovery, development, and delivery of therapeutics to treat patients with neurological and psychiatric disorders.
Read more
Its product candidates include Azetukalner, a novel, potent Kv7 potassium channel opener which is in Phase 3 clinical development for the treatment of epilepsy, including focal onset seizures, and primary generalized tonic-clonic seizures, as well as neuropsychiatric disorders, such as major depressive disorder and bipolar depression. In addition, the company's Phase 1 Single Ascending Dose/Multiple Ascending Dose products include XEN1701 targeting the sodium channel and XEN1120 targeting the Kv7 potassium channel for the treatment of pain. The company has a license and collaboration agreement with Neurocrine Biosciences, Inc. for the development of NBI-921355, a Nav1.2/1.6 sodium channel inhibitor that is in Phase 1 clinical trials for the treatment of certain types of epilepsy. Xenon Pharmaceuticals Inc. was incorporated in 1996 and is headquartered in Burnaby, Canada.
- Website
- xenon-pharma.com
- Headquarters
- Burnaby, BC, Canada
- Employees
- 358
- Listed
- Nov 5, 2014
- Fiscal year ends
- December
Company profile from EODHD, stored Oct 25, 2026.
Quarterly results
The last 8 fiscal quarters as reported (EODHD). Year over year compares the same quarter a year earlier.
| Quarter | Revenue | YoY | Gross margin | Op. income | Net income |
|---|---|---|---|---|---|
| Jun 2026filed Aug 6, 2026 | — | — | — | -$123.2M | -$110.7M |
| Mar 2026filed May 7, 2026 | — | — | — | -$112.3M | -$102.3M |
| Dec 2025filed Feb 26, 2026 | — | — | — | -$109.8M | -$105.3M |
| Sep 2025filed Nov 3, 2025 | — | — | — | -$96.3M | -$90.9M |
| Jun 2025filed Aug 11, 2025 | — | — | — | -$94.2M | -$84.7M |
| Mar 2025filed May 12, 2025 | $7.5M | — | 100.0% | -$72.7M | -$65.0M |
| Dec 2024filed Feb 27, 2025 | $2.5M | -53.2% | — | -$77.5M | -$65.7M |
| Sep 2024filed Nov 12, 2024 | — | — | — | -$73.7M | -$62.8M |
Fiscal years · last 6
| Fiscal year | Revenue | YoY | Gross margin | Op. income | Net income |
|---|---|---|---|---|---|
| Dec 2025filed Feb 26, 2026 | $7.5M | — | 66.1% | -$373.1M | -$345.9M |
| Dec 2024filed Feb 27, 2025 | — | — | — | -$279.3M | -$234.3M |
| Dec 2023filed Feb 29, 2024 | — | — | — | -$214.1M | -$182.4M |
| Dec 2022filed Mar 1, 2023 | $9.4M | -48.8% | — | -$129.1M | -$125.4M |
| Dec 2021filed Mar 1, 2022 | $18.4M | -42.7% | — | -$79.0M | -$78.9M |
| Dec 2020filed Mar 1, 2021 | $32.2M | +371.0% | — | -$31.3M | -$28.8M |
Short-interest history
FINRA reports open short positions for a settlement date. The publication date is later. These are reported positions, with a separate date for each observation.
Compare the reported short exposure around the dates you bought, sold or watched XENE. A long position benefits from price rises; a short position benefits from falls. A change in these counts does not predict either move.
Settlement Oct 15, 2026
7,348,577 shares short
+1,307,090 shares (+21.6%) vs Sep 30, 2026
8.1% of the stored float. Published Oct 26, 2026.
Settlement Sep 30, 2026
6,041,487 shares short
-403,328 shares (-6.3%) vs Sep 15, 2026
6.6% of the stored float. Published Oct 9, 2026.
Settlement Sep 15, 2026
6,444,815 shares short
+100,680 shares (+1.6%) vs Aug 31, 2026
7.1% of the stored float. Published Sep 24, 2026.
Settlement Aug 31, 2026
6,344,135 shares short
+675,141 shares (+11.9%) vs Aug 14, 2026
7% of the stored float. Published Sep 10, 2026.
Settlement Aug 14, 2026
5,668,994 shares short
+284,518 shares (+5.3%) vs Jul 31, 2026
6.2% of the stored float. Published Aug 25, 2026.
Settlement Jul 31, 2026
5,384,476 shares short
-952,620 shares (-15%) vs Jul 15, 2026
5.9% of the stored float. Published Aug 11, 2026.
Change = this settlement’s shares short − the previous recorded settlement’s shares short; percentage change divides by that earlier count. A zero earlier count has no percentage change. Split-spanning counts are left uncompared. Float percentages use the stored settlement observation, not today’s float.
Source: stored FINRA equity short-interest records, up to six settlements from the last 240 days. FINRA data and reporting dates · How to read short interest
Dividends and stock splits
See the recorded cash amounts and dates behind XENE’s income, and the splits that change its share count. Dates below are stored event records, not confirmation of a payment to your account.
Cash-dividend records
No qualified cash-dividend records are stored. This does not establish that the company pays no dividend.
Up to six Polygon cash-dividend events, including recorded ex-dates within the next 120 days. Amounts retain their recorded currency and decimal precision. Historical amounts are not restated to a common split basis, annualized, or converted to dollars.
For a long holding, compare the ex-date with when you held the shares and check the pay date against your broker’s cash history. Owning the stock today does not establish past entitlement. For a short holding, a dividend can create a payment obligation to the share lender.
Ex-dates and special dividend rules · Short-sale dividend obligations · Dividend data definitions
Split history
No qualified split events are stored. This does not establish that the stock has never split.
Up to six stored split dates through Nov 7, 2026. Equivalent vendor ratios are combined; conflicting ratios are left out. This history may be incomplete.
A split changes the share count and per-share price basis; it does not by itself add investment value. Put your holding’s earlier and later share counts on the same basis before comparing them. This applies to both long shares and shares owed on a short position.
How stock splits workPortfolio context
Sign in to see your position size
We’ll show you if XENE is in your portfolio and how much it contributes.
Sign inMarket context
Loading market dates
Smart money context
Holder IQ: MEDIUM
63 smart-money holders: institutions with a high Holder IQ
Q2 2026, filed Oct 30, 2026
Smart-money 13F trend: distributing (light)
Unlock crowding heatmapUnlock filer discoveryInsider context
Sentiment: neutral
Last trade: buy 37 days ago
Read the insider context evidence
What it means for you
Sign in to read your holdings or watchlist context. No personal position or direction is inferred.
What happened
Stored recent-activity label: neutral. This context label is separate from the scored insider signal read.
Why it can matter
A count of reported activity describes a sample, not purchase conviction, an insider’s intent or a future price move. Neutral is not an all-clear, and absent direction is not neutral evidence.
How we got this
The current context rule reads at most 50 nonduplicate issuer/share-class records filed in the last 90 days. It counts a bullish direction or purchase code P toward bullish, and a bearish direction or sale code S toward bearish. A side must exceed the opposite count by more than two to set its label; otherwise nonzero directional counts produce neutral. Calculation unavailable for this saved label: its counts, exact records, as-of time and rule version are not supplied here. Do not substitute the separate scored read’s different window or denominator.
Where the data comes from
Stored SEC Forms 3/4/5 insider-signal records, ordered by filing date with amendment duplicates excluded. Filing date is not transaction date. The last-trade line locates recent reported activity; it does not date or reconstruct the complete count.
Red flags: 1
Read the insider context evidence
What it means for you
Sign in to read your holdings or watchlist context. No personal position or direction is inferred.
What happened
Stored recent-activity label: neutral. This context label is separate from the scored insider signal read.
Why it can matter
A count of reported activity describes a sample, not purchase conviction, an insider’s intent or a future price move. Neutral is not an all-clear, and absent direction is not neutral evidence.
How we got this
The current context rule reads at most 50 nonduplicate issuer/share-class records filed in the last 90 days. It counts a bullish direction or purchase code P toward bullish, and a bearish direction or sale code S toward bearish. A side must exceed the opposite count by more than two to set its label; otherwise nonzero directional counts produce neutral. Calculation unavailable for this saved label: its counts, exact records, as-of time and rule version are not supplied here. Do not substitute the separate scored read’s different window or denominator.
Where the data comes from
Stored SEC Forms 3/4/5 insider-signal records, ordered by filing date with amendment duplicates excluded. Filing date is not transaction date. The last-trade line locates recent reported activity; it does not date or reconstruct the complete count.
Largest 13-F holders · Q2 2026
318 filers reported a long position in XENE for Q2 2026. 13-F holdings are filed up to 45 days after the quarter ends.
The top 10 hold
46%
of the 101.1M shares 13-F filers reported
Moves vs Q1 2026
5 added3 trimmed
1 unchanged · 1 not comparable
Net shares held
+11.4%
across the 9 holders with a comparable Q1 2026 book
| Rank | Holder | Value | Shares | Shares vs Q1 2026 |
|---|---|---|---|---|
| 1 | FMR LLC | $582.4M · 9.6M shares | 9.6M | -10.8% |
| 2 | BlackRock, Inc. | $454.1M · 7.5M shares | 7.5M | +33.4% |
| 3 | Avoro Capital Advisors LLC | $348.7M · 5.8M shares | 5.8M | Unchanged |
| 4 | Polar Capital Holdings Plc | $275.9M · 4.6M shares | 4.6M | +3.8% |
| 5 | DRIEHAUS CAPITAL MANAGEMENT LLC | $266.7M · 4.4M shares | 4.4M | -1.6% |
| 6 | Jupiter Topco LLC | $252.7M · 4.2M shares | 4.2M | — |
| 7 | PRICE T ROWE ASSOCIATES INC /MD/ | $196.1M · 3.2M shares | 3.2M | +144.3% |
| 8 | JPMORGAN CHASE & CO | $157.4M · 2.6M shares | 2.6M | +36.1% |
| 9 | Capital International Investors | $142.5M · 2.4M shares | 2.4M | -11.7% |
| 10 | T. Rowe Price Investment Management, Inc. | $130.9M · 2.2M shares | 2.2M | +127.8% |
Sign in to see each holder’s Holder IQ, factor-adjusted Holder IQ and rank, and compare these holders with all scored filers. Available on every plan.
Sign in5% holder filings (13D / 13G)
Holders of more than 5% of XENE file with the SEC within days. A 13D holder may seek to influence the company; a 13G holder is passive. Each holder’s latest filing from the last three years.
| Filed | Holder | % of class |
|---|---|---|
| Nov 6, 2026 | T. Rowe Price Investment Management, Inc.13G · passive · amended | 10.3% |
| Nov 5, 2026 | FMR LLC13G · passive · amended | 11.5% |
| Aug 13, 2026 | WELLINGTON MANAGEMENT GROUP LLP13G · passive · amended | 1.5%under 5% |
| May 15, 2026 | JANUS HENDERSON GROUP PLC13G · passive · amended | 4.5%under 5% |
| May 15, 2026 | DRIEHAUS CAPITAL MANAGEMENT LLC13G · passive · amended | 4.87%under 5% |
| May 15, 2026 | Avoro Capital Advisors LLC13G · passive · amended | 6.26% |
Get the Full Analysis for XENE
Unlock detailed insider transactions, institutional holder changes, factor exposures, and personalized alerts. Start free with your own portfolio.