Janux Therapeutics Inc

Trading arrangements

During the three months ended June 30, 2024, no director or officer adopted orterminated any Rule 10b5-1 trading arrangement or any non-Rule 10b5-1 trading arrangement (as such terms are defined pursuant to Item 408(a) of Regulation S-K), except as follows:

On June 21, 2024, David Campbell, Ph.D., our President and Chief Executive Officer, adopted a Rule 10b5-1 trading arrangement that is intended to satisfy the affirmative defense of Rule 10b5-1(c) for the sale of up to 120,000 shares of the Company's common stock until September 27, 2025.

On June 28, 2024, Tommy DiRaimondo, Ph.D., our Chief Scientific Officer, adopted a Rule 10b5-1 trading arrangement that is intended to satisfy the affirmative defense of Rule 10b5-1(c) for the sale of up to 96,100 shares of the Company's common stock until June 27, 2025.

Transition of Acting Chief Financial Officer

On August 2, 2024, Tighe Reardon resigned from his position as our Acting Chief Financial Officer, effective as of August 8, 2024 (the Transition Date). In connection with Mr. Reardon’s resignation, we entered into a transition and consulting agreement with Mr. Reardon (the Transition Agreement).

Following the Transition Date, Mr. Reardon has agreed to be available to consult with and advise the Company through December 31, 2024 (the Consulting Period). Mr. Reardon will receive (i) continued vesting of his equity awards through the Consulting Period, and (ii) subject to the satisfaction of certain specified conditions, will receive accelerated vesting of his unvested equity awards that would have vested through June 30, 2026 and an extension of the post-service exercise period for such equity awards until the earliest of December 31, 2027 and the original expiration date of the equity awards, in each case, subject to his continued service through the Consulting Period.

Mr. Reardon is not entitled to receive any benefits pursuant to our 2021 Change in Control and Severance Benefit Plan (a copy of which is filed as Exhibit 10.12 to our Registration Statement on Form S-1 (File No. 333-256297), filed with the SEC on May 19, 2021) in connection with his resignation.

The foregoing description of the Transition Agreement does not purport to be complete and is qualified in its entirety by reference to the actual Transition Agreement, a copy of which will be filed with our Quarterly Report on Form 10-Q for the fiscal quarter ending September 30, 2024, to be filed with the SEC.

Appointment of David Campbell, Ph.D. as Principal Financial Officer and Maria Dobek as Principal Accounting Officer

On August 2, 2024, in connection with Mr. Reardon’s separation from the Company, the Board appointed David Campbell, Ph.D., the Company’s President and Chief Executive Officer, as the Company’s Principal Financial Officer (PFO) and Maria Dobek, the Company’s Vice President, Accounting, as the Company’s Principal Accounting Officer (PAO), in each case, effective as of August 8, 2024.

Ms. Dobek, age 35, joined the Company in March 2021, served as our Controller until July 2024 and is currently serving as our Vice President, Accounting. Prior to joining the Company, Ms. Dobek served in various roles at Ernst & Young LLP from January 2012 to February 2021, most recently as Assurance Senior Manager. Ms. Dobek is a Certified Public Accountant and holds a B.B.A. and Masters in Accounting from the University of Georgia.

There are no arrangements or understandings between Dr. Campbell or Ms. Dobek and any other persons pursuant to which they were appointed as PFO and PAO, respectively. There are no family relationships between Dr. Campbell or Ms. Dobek and any of the Company’s directors or executive officers and Dr. Campbell and Ms. Dobek have no direct or indirect material interest in any transaction required to be disclosed by the Company pursuant to Item 404(a) of Regulation S-K.