TLPH
Talphera Inc.NASDAQ
Healthcare • Drug Manufacturers - Specialty & Generic
$1.05+3.96%
Close Nov 6, 2026
- Market cap
- —
- 1 month
- -2.8%
- 3 months
- -25.5%
- 1 year
- -17.3%
- 52-week range
- $0.72$1.47
- Dividend
- No dividends on record
- Short interest
- 4.2% of float1.1M shares · settled Oct 15, 2026 · +47.7% since Sep 30, 2026 · FINRA
Fundamentals · trailing 12 months to Jun 30, 2026
- Revenue
- $1K
- Net income
- -$15.08M
- Free cash flow
- -$12.27M
- Book value
- $14.41M
- Total debt
- —
- P/E
- —
- Price / sales
- —
- Price / book
- —
- FCF yield
- —
- Net margin
- -1,507,600.0%
EODHD (TTM) · as of Nov 6, 2026
End-of-day close from stored market data, not a live quote.
About Talphera Inc.
Talphera, Inc., a specialty pharmaceutical company, focuses on the development and commercialization of therapies for use in medically supervised settings. The company's lead product candidate, Niyad, is a lyophilized formulation of nafamostat that acts as a regional anticoagulant for infusion into the extracorporeal circuit.
Read more
It is also developing LTX-608, a lyophilized vial containing nafamostat for IV infusion for disseminated intravascular coagulation, acute respiratory distress syndrome, acute pancreatitis, and an anti-viral treatment; Fedsyra, an ephedrine pre-filled syringe for injection; and a phenylephrine pre-filled syringe for injection. The company was formerly known as AcelRx Pharmaceuticals, Inc. and changed its name to Talphera, Inc. in January 2024. The company was incorporated in 2005 and is headquartered in San Mateo, California.
- Website
- talphera.com
- Headquarters
- San Mateo, CA, United States
- Employees
- 12
- Listed
- Feb 11, 2011
- Fiscal year ends
- December
Company profile from EODHD, stored Oct 28, 2026.
Quarterly results
The last 8 fiscal quarters as reported (EODHD). Year over year compares the same quarter a year earlier.
| Quarter | Revenue | YoY | Gross margin | Op. income | Net income |
|---|---|---|---|---|---|
| Jun 2026filed Aug 12, 2026 | — | — | — | -$3.9M | -$4.3M |
| Mar 2026filed May 13, 2026 | — | — | — | -$3.9M | -$2.6M |
| Dec 2025filed Mar 23, 2026 | — | — | — | -$3.5M | -$3.8M |
| Sep 2025filed Nov 12, 2025 | $1.0K | — | 100.0% | -$3.4M | -$4.4M |
| Jun 2025filed Aug 14, 2025 | — | — | — | -$3.7M | -$3.5M |
| Mar 2025filed May 14, 2025 | $27.0K | — | -4,229.6% | -$2.9M | -$2.6M |
| Dec 2024filed Mar 31, 2025 | — | — | — | — | — |
| Sep 2024filed Nov 13, 2024 | — | — | — | -$3.7M | -$3.4M |
Short-interest history
FINRA reports open short positions for a settlement date. The publication date is later. These are reported positions, with a separate date for each observation.
Compare the reported short exposure around the dates you bought, sold or watched TLPH. A long position benefits from price rises; a short position benefits from falls. A change in these counts does not predict either move.
Settlement Oct 15, 2026
1,065,727 shares short
+344,193 shares (+47.7%) vs Sep 30, 2026
4.2% of the stored float. Published Oct 26, 2026.
Settlement Sep 30, 2026
721,534 shares short
+20,811 shares (+3%) vs Sep 15, 2026
2.9% of the stored float. Published Oct 9, 2026.
Settlement Sep 15, 2026
700,723 shares short
+192,096 shares (+37.8%) vs Aug 31, 2026
Share of float unavailable. Published Sep 24, 2026.
Settlement Aug 31, 2026
508,627 shares short
-6,528 shares (-1.3%) vs Aug 14, 2026
Share of float unavailable. Published Sep 10, 2026.
Settlement Aug 14, 2026
515,155 shares short
-190,491 shares (-27%) vs Jul 31, 2026
Share of float unavailable. Published Aug 25, 2026.
Settlement Jul 31, 2026
705,646 shares short
-175,716 shares (-19.9%) vs Jul 15, 2026
Share of float unavailable. Published Aug 11, 2026.
Change = this settlement’s shares short − the previous recorded settlement’s shares short; percentage change divides by that earlier count. A zero earlier count has no percentage change. Split-spanning counts are left uncompared. Float percentages use the stored settlement observation, not today’s float.
Source: stored FINRA equity short-interest records, up to six settlements from the last 240 days. FINRA data and reporting dates · How to read short interest
Dividends and stock splits
See the recorded cash amounts and dates behind TLPH’s income, and the splits that change its share count. Dates below are stored event records, not confirmation of a payment to your account.
Cash-dividend records
No qualified cash-dividend records are stored. This does not establish that the company pays no dividend.
Up to six Polygon cash-dividend events, including recorded ex-dates within the next 120 days. Amounts retain their recorded currency and decimal precision. Historical amounts are not restated to a common split basis, annualized, or converted to dollars.
For a long holding, compare the ex-date with when you held the shares and check the pay date against your broker’s cash history. Owning the stock today does not establish past entitlement. For a short holding, a dividend can create a payment obligation to the share lender.
Ex-dates and special dividend rules · Short-sale dividend obligations · Dividend data definitions
Split history
1 for 20 · reverse split
Effective Oct 26, 2022
Each 20 pre-split shares become 1 post-split share.
Source: EODHD
Up to six stored split dates through Nov 7, 2026. Equivalent vendor ratios are combined; conflicting ratios are left out. This history may be incomplete.
A split changes the share count and per-share price basis; it does not by itself add investment value. Put your holding’s earlier and later share counts on the same basis before comparing them. This applies to both long shares and shares owed on a short position.
How stock splits workPortfolio context
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Smart money context
Holder IQ: HIGH
15 smart-money holders: institutions with a high Holder IQ
Q2 2026, filed Sep 22, 2026
Smart-money 13F trend: accumulating (light)
Unlock crowding heatmapUnlock filer discoveryInsider context
Sentiment: unknown
No recent insider trades detected.
Read the insider context evidence
What it means for you
Sign in to read your holdings or watchlist context. No personal position or direction is inferred.
What happened
No directional recent-activity label is available. This context label is separate from the scored insider signal read.
Why it can matter
A count of reported activity describes a sample, not purchase conviction, an insider’s intent or a future price move. Neutral is not an all-clear, and absent direction is not neutral evidence.
How we got this
The current context rule reads at most 50 nonduplicate issuer/share-class records filed in the last 90 days. It counts a bullish direction or purchase code P toward bullish, and a bearish direction or sale code S toward bearish. A side must exceed the opposite count by more than two to set its label; otherwise nonzero directional counts produce neutral. Calculation unavailable for this saved label: its counts, exact records, as-of time and rule version are not supplied here. Do not substitute the separate scored read’s different window or denominator.
Where the data comes from
Stored SEC Forms 3/4/5 insider-signal records, ordered by filing date with amendment duplicates excluded. Filing date is not transaction date. The last-trade line locates recent reported activity; it does not date or reconstruct the complete count.
Red flags: 6
Read the insider context evidence
What it means for you
Sign in to read your holdings or watchlist context. No personal position or direction is inferred.
What happened
No directional recent-activity label is available. This context label is separate from the scored insider signal read.
Why it can matter
A count of reported activity describes a sample, not purchase conviction, an insider’s intent or a future price move. Neutral is not an all-clear, and absent direction is not neutral evidence.
How we got this
The current context rule reads at most 50 nonduplicate issuer/share-class records filed in the last 90 days. It counts a bullish direction or purchase code P toward bullish, and a bearish direction or sale code S toward bearish. A side must exceed the opposite count by more than two to set its label; otherwise nonzero directional counts produce neutral. Calculation unavailable for this saved label: its counts, exact records, as-of time and rule version are not supplied here. Do not substitute the separate scored read’s different window or denominator.
Where the data comes from
Stored SEC Forms 3/4/5 insider-signal records, ordered by filing date with amendment duplicates excluded. Filing date is not transaction date. The last-trade line locates recent reported activity; it does not date or reconstruct the complete count.
Largest 13-F holders · Q2 2026
49 filers reported a long position in TLPH for Q2 2026. 13-F holdings are filed up to 45 days after the quarter ends.
The top 10 hold
90%
of the 23.9M shares 13-F filers reported
Moves vs Q1 2026
3 added2 trimmed
5 unchanged
Net shares held
+11.9%
across the 10 holders with a comparable Q1 2026 book
| Rank | Holder | Value | Shares | Shares vs Q1 2026 |
|---|---|---|---|---|
| 1 | Rosalind Advisors, Inc. | $5.3M · 5.2M shares | 5.2M | +54.1% |
| 2 | AIGH Capital Management LLC | $4.7M · 4.6M shares | 4.6M | -1.3% |
| 3 | Rock Springs Capital Management LP | $3.7M · 3.6M shares | 3.6M | Unchanged |
| 4 | Nantahala Capital Management, LLC | $3.6M · 3.5M shares | 3.5M | Unchanged |
| 5 | Bleichroeder LP | $1.3M · 1.3M shares | 1.3M | Unchanged |
| 6 | CANTOR FITZGERALD, L. P. | $914.1K · 887.5K shares | 887.5K | Unchanged |
| 7 | Dauntless Investment Group, LLC | $768.4K · 746.1K shares | 746.1K | +71.4% |
| 8 | VANGUARD CAPITAL MANAGEMENT LLC | $722.9K · 701.9K shares | 701.9K | +58.9% |
| 9 | Caption Management, LLC | $530.4K · 515K shares | 515K | -8.3% |
| 10 | Almitas Capital LLC | $481.2K · 467.2K shares | 467.2K | Unchanged |
Sign in to see each holder’s Holder IQ, factor-adjusted Holder IQ and rank, and compare these holders with all scored filers. Available on every plan.
Sign in5% holder filings (13D / 13G)
Holders of more than 5% of TLPH file with the SEC within days. A 13D holder may seek to influence the company; a 13G holder is passive. Each holder’s latest filing from the last three years.
| Filed | Holder | % of class |
|---|---|---|
| Aug 12, 2026 | Rosalind Advisors, Inc.13G · passive · amended | 9.9% |
| May 15, 2026 | LYTTON LAURENCE W13G · passive · amended | 2.5%under 5% |
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