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Xeris Biopharma Holdings, Inc.

For the period ended Dec 31, 2025. Filed Mar 2, 2026.

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About this filing

A company's yearly report to the SEC, with audited financial statements. It is the fullest account a company gives of its business, its finances and the risks it sees.

FY2025 · Filed Mar 2, 2026

XERS$15.86+4.3%Stored close · as of Nov 9, 2026

Extracted filing text, with the paragraph anchors used by the comparison.

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Contents

Table of Contents

Index to Annual Report on Form 10-K

Year Ended December 31, 2025

Page
Cautionary Statements for Forward-Looking Information4
Part I.
Item 1. Business6
Item 1A. Risk Factors29
Item 1B. Unresolved Staff Comments71
Item 1C. Cybersecurity71
Item 2. Properties72
Item 3. Legal Proceedings72
Item 4. Mine Safety Disclosures72
Part II.
Item 5. Market for Registrant’s Common Equity, Related Stockholder Matters and Issuer Purchases of Equity Securities73
Item 6. [Reserved]74
Item 7. Management's Discussion and Analysis of Financial Condition and Results of Operations75
Item 7A. Quantitative and Qualitative Disclosures About Market Risk81
Item 8. Financial Statements and Supplementary Data82
Item 9. Changes in and Disagreements with Accountants on Accounting and Financial Disclosure113
Item 9A. Controls and Procedures113
Item 9B. Other Information113
Item 9C. Disclosure Regarding Foreign Jurisdictions that Prevent Inspections113
Part III.
Item 10. Directors, Executive Officers and Corporate Governance114
Item 11. Executive Compensation114
Item 12. Security Ownership of Certain Beneficial Owners and Management and Related Stockholder Matters114
Item 13. Certain Relationships and Related Transactions, and Director Independence114
Item 14. Principal Accountant Fees and Services114
Part IV.
Item 15. Exhibits and Financial Statement Schedules115
Index to Exhibits116
Signatures121

Solely for convenience, the trademarks and trade names in this Annual Report on Form 10-K (this "Annual Report") are referred to without the ® and ™ symbols, but absence of such references should not be construed as any indicator that their respective owners will not assert, to the fullest extent under applicable law, their rights thereto. The trademarks, trade names, and service marks appearing in this Annual Report are the property of their respective owners.

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The text of this filing, as the company filed it with the SEC, without its images or exhibits. This is not investment advice.