Denali Therapeutics Inc.
For the period ended Sep 30, 2025. Filed Nov 6, 2025.
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A company's report for each of its first three quarters. The financial statements are not audited. It shows how the business has moved since the last annual report, and what management says changed.
Sep 30, 2025 · Filed Nov 6, 2025
DNLI$19.85-2.4%Stored close · as of Nov 10, 2026
Extracted filing text, with the paragraph anchors used by the comparison.
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Condensed Consolidated Statements of Operations and Comprehensive Loss
(In thousands, except share and per share amounts)
| Three Months Ended September 30, | Nine Months Ended September 30, | |||
|---|---|---|---|---|
| 2025 | 2024 | 2025 | 2024 | |
| Operating expenses: | ||||
| Research and development | $101,950 | $98,238 | $320,873 | $296,653 |
| General and administrative | 35,484 | 24,949 | 97,104 | 75,379 |
| Total operating expenses | 137,434 | 123,187 | 417,977 | 372,032 |
| Gain from divestiture of small molecule programs | — | — | — | 14,537 |
| Loss from operations | (137,434) | (123,187) | (417,977) | (357,495) |
| Interest and other income, net | 10,532 | 15,995 | 33,986 | 49,475 |
| Net loss | $(126,902) | $(107,192) | $(383,991) | $(308,020) |
| Net loss per share, basic and diluted | $(0.74) | $(0.63) | $(2.24) | $(1.89) |
| Weighted average number of shares outstanding, basic and diluted | 172,421,492 | 169,456,988 | 171,702,183 | 162,589,325 |
| Comprehensive loss | ||||
| Net loss | $(126,902) | $(107,192) | $(383,991) | $(308,020) |
| Other comprehensive income (loss): | ||||
| Net unrealized gain (loss) on marketable securities, net of tax | 162 | 8,188 | (919) | 4,886 |
| Comprehensive loss | $(126,740) | $(99,004) | $(384,910) | $(303,134) |
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