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Vaxcyte, Inc.

For the period ended Dec 31, 2025. Filed Feb 24, 2026.

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About this filing

A company's yearly report to the SEC, with audited financial statements. It is the fullest account a company gives of its business, its finances and the risks it sees.

FY2025 · Filed Feb 24, 2026

PCVX$67.53+5.7%Stored close · as of Nov 9, 2026

Extracted filing text, with the paragraph anchors used by the comparison.

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Contents

Item 16. Form 10-K Summary

None.

Exhibit Index

Incorporated by Reference
ExhibitDescriptionFormFile NumberExhibitFiling Date
3.1 · Second Amended and Restated Certificate of Incorporation of Vaxcyte, Inc. · X
3.2Amended and Restated Bylaws of Vaxcyte, Inc., as amended.10-Q001-393233.2November 6, 2023
4.1Form of Common Stock Certificate of the Registrant.S-1/A333-2386304.1June 8, 2020
4.2Description of Capital Stock.10-K001-393234.2March 29, 2021
4.3Form of Pre-Funded Warrant.8-K001-393234.1January 13, 2022
4.4Form of Pre-Funded Warrant.8-K001-393234.1October 27, 2022
4.5Form of Pre-Funded Warrant.8-K001-393234.1April 20, 2023
4.6Form of Pre-Funded Warrant.8-K001-393234.1January 31, 2024
4.7Form of Pre-Funded Warrant.8-K001-393234.1September 6, 2024
10.1#Vaxcyte, Inc. Amended and Restated 2014 Equity Incentive Plan and forms of agreements thereunder.S-1333-23863010.2May 22, 2020
10.2#Vaxcyte, Inc. 2020 Equity Incentive Plan.10-Q001-3932310.1August 8, 2023
10.3#Form of Stock Option Grant Notice and Stock Option Agreement (2020 Equity Incentive Plan).10-Q001-3932310.2August 8, 2023
Incorporated by Reference
ExhibitDescriptionFormFile NumberExhibitFiling Date
10.4#Form of Restricted Stock Unit Grant Notice (2020 Equity Incentive Plan).10-Q001-3932310.2May 9, 2022
10.5#Vaxcyte, Inc. 2020 Employee Stock Purchase Plan.S-1/A333-23863010.4June 8, 2020
10.6Form of Indemnification Agreement entered into by and between the Registrant and each director and executive officer.S-1333-23863010.5May 22, 2020
10.7#Executive Employment Agreement entered into by and between the Registrant and Grant Pickering, dated January 21, 2016.S-1333-23863010.6May 22, 2020
10.8#Executive Employment Agreement entered into by and between the Registrant and Jim Wassil, dated November 15, 2019.S-1333-23863010.11May 22, 2020
10.9#Offer Letter entered into by and between the Registrant and Andrew Guggenhime, dated April 16, 2020.S-1333-23863010.13May 22, 2020
10.10#Offer Letter entered into by and between the Registrant and Mikhail Eydelman, dated March 4, 2022.10-Q001-3932310.1May 9, 2022
10.11#Offer Letter entered into by and between Registrant and Harp Dhaliwal, dated September 29, 2021.X
10.12#Form of Executive Change in Control and Severance Agreement entered into by and between the Registrant and each eligible employee.S-1333-23863010.14May 22, 2020
10.13#Form of Amendment to Executive Change in Control and Severance Agreements entered into by and between the Registrant and each eligible employee.8-K001-3932310.1December 19, 2025
10.14+†Master Services Agreement for Drug Product Development and Manufacturing between Registrant and Lonza Ltd., dated March 22, 2022, as amended.10-K001-3932310.12February 27, 2024
10.15+†Development and Manufacturing Services Agreement by and between the Registrant and Lonza Ltd., dated March 1, 2023.10-Q001-3932310.1May 8, 2023
10.16+†Commercial Manufacturing and Supply Agreement by and between the Registrant and Lonza Ltd., dated October 13, 2023.10-K001-3932310.14February 27, 2024
10.17+†Amended and Restated SutroVax Agreement by and between the Registrant and Sutro Biopharma, Inc., dated October 12, 2015, as amended.S-1333-23863010.18May 22, 2020
Incorporated by Reference
ExhibitDescriptionFormFile NumberExhibitFiling Date
10.18+†Third Amendment to Amended and Restated SutroVax Agreement by and between Sutro Biopharma, Inc. and the Registrant, dated September 28, 2023.10-Q001-3932310.3November 6, 2023
10.19+†Supply Agreement by and between the Registrant and Sutro Biopharma, Inc., dated May 29, 2018, as amended.10-K001-3932310.19February 27, 2023
10.20+†Option Grant Agreement by and between Registrant and Sutro Biopharma, Inc., dated December 19, 2022.10-K001-3932310.20February 27, 2023
10.21+†Manufacturing Rights Agreement by and between the Registrant and Sutro Biopharma, Inc., dated November 21, 2023.10-K001-3932310.19February 27, 2024
10.22+†License Agreement by and between the Registrant and The Regents of the University of California, represented by its San Diego campus, dated February 4, 2019.S-1333-23863010.20May 22, 2020
10.23First Amendment to License Agreement by and between the Registrant and The Regents of the University of California, represented by its San Diego campus, dated August 16, 2019.10-K001-3932310.21February 27, 2024
10.24+†Amended and Restated Lease Agreement by and between the Registrant and ARE-San Francisco No. 63, LLC, dated as of November 15, 2024.10-K001-3932310.22February 25, 2025
10.25#Form of Non-U.S. Stock Option Grant Notice and Stock Option Agreement (2020 Equity Incentive Plan).10-K001-3932310.26February 27, 2024
10.26#Form of Non. U.S. Restricted Stock Unit Grant Notice (2020 Equity Incentive Plan).10-K001-3932310.27February 27, 2024
10.27#Form of Performance Restricted Stock Unit Award Grant Notice and Agreement.10-Q001-3932310.1May 7, 2025
10.28#Form of Performance Contingent Stock Option Grant Notice and Agreement.10-Q001-3932310.2May 7, 2025
10.29+†Commercial Manufacturing and Supply Agreement by and between the Registrant and Patheon Manufacturing Services LLC (part of Thermo Fisher Scientific), dated September 24, 2025.10-Q001-3932310.1November 4, 2025
19.1Vaxcyte, Inc. Insider Trading Policy10-K001-3932319.1February 25, 2025
21.1Subsidiary of Registrant.10-K001-3932321.1February 27, 2024
23.1Consent of Independent Registered Public Accounting Firm.X
24.1Power of Attorney. Reference is made to the signature page hereto.X
Incorporated by Reference
ExhibitDescriptionFormFile NumberExhibitFiling Date
31.1 · Certification of Principal Executive Officer pursuant to Rules 13a-14(a) and 15d-14(a) under the Securities Exchange Act of 1934, as amended. · X
31.2 · Certification of Principal Financial Officer pursuant to Rules 13a-14(a) and 15d-14(a) under the Securities Exchange Act of 1934, as amended. · X
32.1* · Certification of Principal Executive Officer and Principal Financial Officer Pursuant to 13a-14(b) or 15d-14(b) of the Securities Exchange Act, as amended, and 18 U.S.C. Section 1350. · X
97.1#Incentive Compensation Recoupment Policy.10-K001-3932397.1February 27, 2024
101.INSInline XBRL Instance Document – the instance document does not appear in the Interactive Data File because XBRL tags are embedded within the Inline XBRL document.X
101.SCHInline XBRL Taxonomy Extension Schema With Embedded Linkbase Documents.X
104Cover Page Interactive Data File (formatted as inline XBRL and contained in Exhibit 101).X

X Filed herewith.

ContentsView on SEC.gov

The text of this filing, as the company filed it with the SEC, without its images or exhibits. This is not investment advice.