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C4 Therapeutics, Inc.

For the period ended Sep 30, 2026. Filed Nov 5, 2026.

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About this filing

A company's report for each of its first three quarters. The financial statements are not audited. It shows how the business has moved since the last annual report, and what management says changed.

Sep 30, 2026 · Filed Nov 5, 2026

CCCC$3.15+1.6%Stored close · as of Nov 9, 2026

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Item 6. Exhibits

ExhibitNumberDescriptionFormFileNumberDate ofFilingExhibit/AnnexFiledHerewith
3.1Fifth Amended and Restated Certificate of Incorporation of the Registrant8-K001-3956710/06/20203.1
3.2Certificate of Amendment to the Fifth Amended and Restated Certificate of Incorporation of the RegistrantDEF14A001-3956704/28/2023A
3.3Certificate of Amendment to the Fifth Amended and Restated Certificate of Incorporation of the Registrant8-K001-3956706/18/20253.1
3.4Second Amended and Restated By-laws of the RegistrantS-1333-24871909/10/20203.5
3.5Amendment No. 1 to Second Amended and Restated By-laws of C4 Therapeutics, Inc.8-K001-3956704/10/20263.1
10.1†Third Amendment to Amended and Restated License Agreement, dated August 14, 2026, by and among C4 Therapeutics, Inc., F. Hoffmann-La Roche Ltd and Hoffmann-La Roche Inc.X
31.1Certification of Principal Executive Officer Pursuant to Rules 13a-14(a) and 15d-14(a) under the Securities Exchange Act of 1934, as Adopted Pursuant to Section 302 of the Sarbanes-Oxley Act of 2002.X
31.2Certification of Principal Financial Officer Pursuant to Rules 13a-14(a) and 15d-14(a) under the Securities Exchange Act of 1934, as Adopted Pursuant to Section 302 of the Sarbanes-Oxley Act of 2002.X
32.1*Certification of Principal Executive Officer Pursuant to 18 U.S.C. Section 1350, as Adopted Pursuant to Section 906 of the Sarbanes-Oxley Act of 2002.X
32.2*Certification of Principal Financial Officer Pursuant to 18 U.S.C. Section 1350, as Adopted Pursuant to Section 906 of the Sarbanes-Oxley Act of 2002.X
101.INSXBRL Instance Document - the instance document does not appear in the Interactive Data File because its XBRL tags are embedded within the Inline XBRL document
101.SCHInline XBRL Taxonomy Extension Schema Document
101.CALInline XBRL Taxonomy Calculation Linkbase Document
101.DEFInline XBRL Taxonomy Extension Definition Linkbase Document
101.LABInline XBRL Taxonomy Label Linkbase Document
ExhibitNumberDescriptionFormFileNumberDate ofFilingExhibit/AnnexFiledHerewith
101.PREInline XBRL Taxonomy Presentation Linkbase Document
104Cover Page Interactive Data File (embedded within the Inline XBRL document)

*Exhibits 32.1 and 32.2 are being furnished herewith and shall not be deemed to be “filed” for purposes of Section 18 of the Exchange Act, or otherwise subject to the liability of that section, nor shall such exhibits be deemed to be incorporated by reference in any registration statement or other document filed under the Securities Act, or the Exchange Act, except as otherwise stated in such filing.

† Portions of this exhibit (indicated by asterisks) have been omitted in accordance with the rules of the Securities and Exchange Commission.

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The text of this filing, as the company filed it with the SEC, without its images or exhibits. This is not investment advice.