Vir Biotechnology, Inc.

Director and Officer Trading Arrangements

A portion of the compensation of the Company’s directors and officers (as defined in Rule 16a-1(f) under the Exchange Act) is in the form of equity awards and, from time to time, directors and officers may engage in open-market transactions with respect to the securities acquired pursuant to such equity awards or other Company securities, including to satisfy tax withholding obligations when equity awards vest or are exercised, and for diversification or other personal reasons.

Transactions in Company securities by directors and officers are required to be made in accordance with the Company’s insider trading policy, which requires that the transactions be in accordance with applicable U.S. federal securities laws that prohibit trading while in possession of material non-public information. Rule 10b5-1 under the Exchange Act provides an affirmative defense that enables directors and officers to prearrange transactions in the Company’s securities in a manner that avoids concerns about initiating transactions while in possession of material non-public information.

During the quarterly period covered by this report, none of our directors or officers entered into orterminated a Rule 10b5-1 trading arrangement or adopted or terminated a non-Rule 10b5-1 trading arrangement (as defined in Item 408(c) of Regulation S-K) except as follows:

On February 22, 2026, the Company issued restricted stock units (RSUs) subject to mandatory sell-to-cover tax withholding arrangements intended to satisfy the affirmative defense conditions of Exchange Act Rule 10b5-1(c) to the following officers of the Company:

•Marianne De Backer, M.Sc., Ph.D., MBA, our President and Chief Executive Officer;

•Vanina de Verneuil, J.D., our Executive Vice President, General Counsel and Corporate Secretary;

•Mark Eisner, M.D., M.P.H., our then-serving Executive Vice President and Chief Medical Officer;

•Jason O’Byrne, MBA, our Executive Vice President and Chief Financial Officer; and

•Brent Sabatini, CPA, MBA, our Senior Vice President and Chief Accounting Officer.