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Midas Edge

GRAIL, Inc.

For the period ended Dec 31, 2025. Filed Mar 12, 2026.

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About this filing

A company's yearly report to the SEC, with audited financial statements. It is the fullest account a company gives of its business, its finances and the risks it sees.

FY2025 · Filed Mar 12, 2026

GRAL$124.74-2.6%Stored close · as of Nov 10, 2026

Extracted filing text, with the paragraph anchors used by the comparison.

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Contents

Item 15. Exhibits, Financial Statement Schedules

(a) Documents filed as part of this report

(1) Financial Statements:

Consolidated Financial Statements of GRAIL, Inc. are included in Part II, Item 8 of this Annual Report.

(2) Financial Statement Schedules:

Financial statement schedules are omitted as the required information is either inapplicable or the information is presented in our Consolidated Financial Statements or notes thereto.

(3) Exhibits

The exhibits listed in the Exhibit Index in (b) below are filed or incorporated by reference as part of this Annual Report.

a. Exhibit Index

The following documents are filed as exhibits hereto:

Exhibit Number · Exhibit Description · Incorporated by Reference · Filed / Furnished Herewith
Form · File No. · Exhibit · Filing Date
2.1Separation and Distribution Agreement, dated June 21, 2024, by and among Illumina, Inc. and GRAIL, Inc.8-K001-420452.16/24/24
3.1Certificate of Incorporation of GRAIL, Inc., dated June 21, 20248-K001-420453.16/24/24
3.2Amended and Restated Bylaws of GRAIL, Inc., Dated June 21, 20248-K001-420453.26/24/24
3.3Certificate of Conversion8-K001-420453.36/24/24
4.1Description of Securities10-K001-420454.13/5/25
4.2Form of Pre-Funded Warrant to Purchase Common Stock8-K001-420454.110/20/25
4.3Form of IndentureS-3ASR333-2915034.211/13/25
10.1Tax Matters Agreement between GRAIL, LLC and Illumina, Inc.8-K001-4204510.16/24/24
10.2Employee Matters Agreement between GRAIL, LLC and Illumina, Inc.8-K001-4204510.26/24/24
10.3Stockholder and Registration Rights Agreement between GRAIL, LLC and Illumina, Inc.8-K001-4204510.36/24/24
10.4Agreement and Plan of Merger, dated as of September 20, 2020, among Illumina, Inc., SDG Ops, Inc., SDG Ops, LLC and GRAIL, Inc.10-12B001-4204510.45/6/24
10.5Amendment to the Agreement and Plan of Merger, dated as of September 20, 2020, among Illumina, Inc., SDG Ops, Inc., SDG Ops, LLC and GRAIL, Inc., dated as of February 4, 202110-12B001-4204510.55/6/24
10.6†Amended and Restated Supply and Commercialization Agreement, dated as of February 28, 2017, by and between Illumina, Inc. and GRAIL, Inc., as amended on September 27, 2017, August 18, 2021 and on May 18, 202310-12B001-4204510.65/6/24
10.7†Fourth Amendment to the Amended and Restated Supply and Commercialization Agreement by and between Illumina, Inc. and GRAIL, LLC8-K001-4204510.76/24/24
10.8#GRAIL, Inc. 2024 Incentive Award Plan8-K001-4204510.17/2/24
10.9#Form Restricted Stock Unit Agreement10-12B/A001-4204510.95/29/24
10.10#Form of Stock Option Agreement10-12B/A001-4204510.105/29/24
10.11#Form of Indemnification Agreement between GRAIL, LLC and each of its directors and executive officers10-12B/A001-4204510.115/29/24
10.12#GRAIL, Inc. 2024 Employee Stock Purchase Plan8-K001-4204510.27/2/24
10.13#Form of Cash-Based Equity Appreciation Award Agreement10-12B/A001-4204510.135/29/24
10.14#Employment Offer Letter, between GRAIL, LLC and Robert Ragusa, dated October 14, 202110-12B/A001-4204510.145/29/24
10.15#Transition, Separation and Release Agreement, between GRAIL, Inc. and Robert Ragusa, dated March 11, 2026*
10.16#Form of Amended Offer Letter,8-K001-4204510.15/16/25
10.17†License Agreement by and between The Chinese University of Hong Kong and Cirina Limited (No. TC1510005), dated as of April 7, 2016, as amended May 29, 201710-12B/A001-4204510.175/29/24
10.18†License Agreement by and between The Chinese University of Hong Kong and Cirina Limited (No. TC1510006), dated as of April 7, 2016, as amended May 29, 201710-12B/A001-4204510.185/29/24
10.19†License Agreement by and between The Chinese University of Hong Kong and Cirina Limited (No. TC1711655), dated as of May 29, 201710-12B/A001-4204510.195/29/24
10.20†License Agreement by and between The Chinese University of Hong Kong and Cirina Limited (No. TC1711656), dated as of May 29, 201710-12B/A001-4204510.205/29/24
10.21†License Agreement by and between The Chinese University of Hong Kong and Cirina Limited (No. TC1711657), dated as of May 29, 201710-12B/A001-4204510.215/29/24
10.22Lease by and between MENLO PREHC I, LLC, MENLO PREPI I, LLC, TPI Investors 9, LLC and GRAIL, Inc., dated as of May 5, 201610-12B/A001-4204510.225/29/24
10.23First Amendment to Lease among MENLO PREHC I, LLC, MENLO PREPI I, LLC, TPI Investors 9, LLC and GRAIL, Inc., dated as of June 8, 201710-12B/A001-4204510.235/29/24
10.24Lease Agreement by and between PP Office Owner 1, L.P. and GRAIL, Inc., dated as of June 4, 202010-12B/A001-4204510.245/29/24
10.25#GRAIL, Inc. Non-Employee Director Compensation Program8-K001-4204510.37/2/24
10.26Lease, dated September 11, 2025, by and between GRAIL, Inc. and Sunnyvale Office Acquisition, LLC8-K001-4204510.19/18/25
10.27Stock Purchase Agreement, dated as of October 16, 2025, by and among GRAIL, Inc., Samsung C&T Corporation, Samsung Electronics Singapore Pte., Ltd. and Samsung Electronics Co., Ltd.8-K001-4204510.110/16/25
10.28Securities Purchase Agreement, dated as of October 18, 2025, by and among GRAIL, Inc. and the Investors named therein8-K001-4204510.110/20/25
10.29Registration Rights Agreement, dated as of October 18, 2025, by and among GRAIL, Inc. and the Investors named therein8-K001-4204510.210/20/25
10.30Equity Distribution Agreement, dated as of November 14, 2025, by and among GRAIL, Inc., Morgan Stanley & Co. LLC and TD Securities (USA) LLC.8-K001-4204510.111/14/2025
19.1Insider Trading Policy10-K001-4204519.13/5/25
21.1List of subsidiaries of GRAIL, Inc.10-12B001-4204521.15/6/24
23.1Consent of Independent Registered Public Accounting Firm*
31.1Certification of Principal Executive Officer Pursuant to Rules 13a-14(a) and 15d-14(a) under the Securities Exchange Act of 1934, as Adopted Pursuant to Section 302 of the Sarbanes-Oxley Act of 2002.*
31.2Certification of Principal Financial Officer Pursuant to Rules 13a-14(a) and 15d-14(a) under the Securities Exchange Act of 1934, as Adopted Pursuant to Section 302 of the Sarbanes-Oxley Act of 2002.*
32.1Certification of Principal Executive Officer Pursuant to 18 U.S.C. Section 1350, as Adopted Pursuant to Section 906 of the Sarbanes-Oxley Act of 2002.**
32.2Certification of Principal Financial Officer Pursuant to 18 U.S.C. Section 1350, as Adopted Pursuant to Section 906 of the Sarbanes-Oxley Act of 2002.**
97.1Policy for Recovery of Erroneously Awarded Compensation10-K001-4204597.13/5/2025
101.INSInline XBRL Instance Document - the instance document does not appear in the Interactive Data File because its XBRL tags are embedded within the Inline XBRL document.*
101.SCHInline XBRL Taxonomy Extension Schema Document*
101.CALInline XBRL Taxonomy Extension Calculation Linkbase Document*
101.DEFInline XBRL Taxonomy Extension Definition Linkbase Document*
101.LABInline XBRL Taxonomy Extension Label Linkbase Document*
101.PREInline XBRL Taxonomy Extension Presentation Linkbase Document*
104Cover Page Interactive Data File (formatted as Inline XBRL and contained in Exhibit 101)*
*Filed herewith.
**Furnished herewith.
#Indicates a management or compensatory plan.
†Pursuant to Item 601(b)(10) of Regulation S-K, portions of this exhibit have been omitted as the registrant has determined that the omitted information is (i) not material and (ii) the type of information that the registrant customarily and actually treats as private or confidential.
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