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TriSalus Life Sciences, Inc.

For the period ended Dec 31, 2025. Filed Mar 5, 2026.

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About this filing

A company's yearly report to the SEC, with audited financial statements. It is the fullest account a company gives of its business, its finances and the risks it sees.

FY2025 · Filed Mar 5, 2026

TLSI$2.85-11.5%Stored close · as of Nov 10, 2026

Extracted filing text, with the paragraph anchors used by the comparison.

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Item 15. Exhibits, Financial Statement Schedules

Item 15. Exhibit and Financial Statement Schedules

(a) The following documents are filed as part of this Form 10-K:

(1)Financial Statements:

Our Consolidated Financial Statements are listed in the “Financial Statements and Supplementary Data” under Part II. Item 8 of this Annual Report on Form 10‑K.

(2)Financial Statement Schedules:

None.

(3)Exhibits

The exhibits filed as part of the Annual Report on Form 10-K are listed in Item 15(b).

(b) Exhibits

The following exhibits are filed as part of this Annual Report on Form 10-K:

Incorporated by Reference
ExhibitDescriptionSchedule/FormFile NumberExhibitsFiling Date
3.1Second Amended and Restated Certificate of Incorporation of TriSalus Life Sciences, Inc.Form 8-K001-398133.1August 16, 2023
3.2Amended and Restated Bylaws of TriSalus Life Sciences, Inc.Form 8-K001-398133.2August 16, 2023
3.3Form of Certificate of Designations, Preferences, and Rights of Series A Convertible Preferred Stock of TriSalus Life Sciences, Inc.Form 8-K001-398133.3August 16, 2023
3.4Certificate of Amendment to Certificate of Designations, Preferences and Rights of Series A Convertible Preferred Stock of TriSalus Life Sciences, Inc.Form 8-K001-398133.1July 24, 2025
4.1Specimen Common Stock CertificateForm 8-K001-398134.1August 16, 2023
4.2Specimen Warrant CertificateForm 8-K001-398134.2August 16, 2023
4.3Warrant Agreement, dated December 17, 2020, by and between MTAC and Continental Stock Transfer & Trust Company.Form 8-K001-398134.1December 23, 2020
4.4Amendment No. 1 to Warrant Agreement, dated June 26, 2024, by and between the Company and Continental Stock Transfer & Trust Company.Form 8-K001-3981310.1June 27, 2024
4.5Description of Securities
4.6Substitute Warrant Certificate, dated August 15, 2024, by and between TriSalus Life Sciences, Inc, and OrbiMed Royalty & Credit Opportunities IV, LP.Form S-3001-398134.10October 29, 2024
4.7Substitute Warrant Certificate, dated August 15, 2024, by and between TriSalus Life Sciences, Inc, and OrbiMed Royalty & Credit Opportunities IV Offshore, LP.Form S-3001-398134.11October 29, 2024
Incorporated by Reference
ExhibitDescriptionSchedule/FormFile NumberExhibitsFiling Date
4.8Warrant Certificate, dated February 18, 2025, by and between TriSalus Life Sciences, Inc., and OrbiMed Royalty & Credit Opportunities IV, L.P.Form 10-K001-398134.10April 15, 2025
4.9Warrant Certificate, dated February 18, 2025, by and between TriSalus Life Sciences, Inc., and OrbiMed Royalty & Credit Opportunities IV Offshore, L.P.Form 10-K001-398134.11April 15, 2025
10.1*TriSalus Life Sciences, Inc. 2023 Equity Incentive PlanForm 8-K001-3981310.21August 16, 2023
10.2*TriSalus Life Sciences, Inc. 2023 Employee Stock Purchase PlanForm 8-K001-3981310.24August 16, 2023
10.3*Surefire Medical, Inc. 2009 Amended and Restated Equity Incentive Plan.Form 8-K001-3981310.15August 16, 2023
10.4*Form of Stock Option Grant Notice and Form of Stock Option Agreement under Surefire Medical, Inc. 2009 Amended and Restated Equity Incentive Plan (Pre-2020).Form 8-K001-3981310.16August 16, 2023
10.5*Form of Early Exercise Stock Option Grant Notice and Form of Stock Option Agreement under Surefire Medical, Inc. 2009 Amended and Restated Equity Incentive Plan (for grants prior to 2020).Form 8-K001-3981310.17August 16, 2023
10.6*Form of Stock Option Grant Notice and Form of Stock Option Agreement under Surefire Medical, Inc. 2009 Amended and Restated Equity Incentive Plan (for grants after 2020).Form 8-K001-3981310.18August 16, 2023
10.7*Form of Early Exercise Stock Option Grant Notice and Form of Stock Option Agreement under Surefire Medical, Inc. 2009 Amended and Restated Equity Incentive Plan (for grants after 2020).Form 8-K001-3981310.19August 16, 2023
10.8*Form of Restricted Stock Unit Grant Notice and Form of Restricted Stock Unit Agreement under Surefire Medical, Inc. 2009 Amended and Restated Equity Incentive Plan.Form 8-K001-3981310.20August 16, 2023
10.9*Form of Stock Option Grant Notice and Form of Stock Option Agreement under 2023 Equity Incentive Plan.Form 8-K001-3981310.22August 16, 2023
10.10*Form of Restricted Stock Unit Grant Notice and Form of Restricted Stock Unit Agreement under 2023 Equity Incentive Plan.Form 8-K001-3981310.23August 16, 2023
10.11*Form of Indemnification Agreement by and between the Company and its directors and executive officers.Form 8-K001-3981310.25August 16, 2023
Incorporated by Reference
ExhibitDescriptionSchedule/FormFile NumberExhibitsFiling Date
10.12*##Amended and Restated Employment Agreement, dated November 11, 2022, by and between TriSalus Life Sciences, Inc. and Mary Szela.Form S-4/A333-26913810.14April 21, 2023
10.13*##Amended and Restated Executive Employment Agreement, dated March 2, 2023, by and between TriSalus Life Sciences, Inc. and Richard Marshak.Form S-4/A333-26913810.17April 21, 2023
10.14*##Executive Employment Agreement, dated November 11, 2022, by and between TriSalus Life Sciences, Inc. and Jennifer L. Stevens.Form S-4/A333-26913810.18April 21, 2023
10.15*##Executive Employment Agreement, dated November 4, 2022, by and between TriSalus Life Sciences, Inc. and Bryan F. Cox, Ph.D.Form S-4/A333-26913810.19April 21, 2023
10.16*##Amended and Restated Executive Employment Agreement, Dated January 6, 2025, by and between TriSalus Life Sciences, Inc. and Jodi Devlin.Form 10-K001-3981310.22April 15, 2025
10.17*##Strategic Collaboration Agreement, dated March 2, 2021, by and between Surefire Medical Inc. d/b/a TriSalus Life Sciences and The University of Texas M.D. Anderson Cancer Center.Form S-4/A333-26913810.20April 21, 2023
10.18*##Office/Warehouse Lease, dated February 4, 2014 between Colorado Industrial Portfolio LLC and Surefire Medical, Inc., as amended.Form S-4/A333-26913810.25July 6, 2023
10.19##Credit Agreement, dated April 30, 2024, by and between TriSalus Operating Life Sciences, Inc., TriSalus Life Sciences, Inc., and OrbiMed Royalty & Credit Opportunities IV, LP.Form 10-Q001-3981310.1May 15, 2024
10.20##First Amendment to Credit Agreement and Registration Rights Agreement by and between TriSalus Operating Life Sciences, Inc., TriSalus Life Sciences, Inc., OrbiMed Royalty & Credit Opportunities IV, LP., and OrbiMed Royalty & Credit Opportunities IV Offshore, LP.Form 10-K001-3981310.26April 15, 2025
10.21*Amendment No. 1 to Amended and Restated Executive Employment Agreement, dated January 24, 2024, by and between TriSalus Life Sciences, Inc. and Richard Marshak.Form 10-K001-3981310.30April 15, 2025
10.22*Amendment No. 2 to Amended and Restated Executive Employment Agreement, dated January 6, 2025, by and between TriSalus Life Sciences, Inc. and Richard Marshak.Form 10-K001-3981310.31April 15, 2025
Incorporated by Reference
ExhibitDescriptionSchedule/FormFile NumberExhibitsFiling Date
10.23Second Amendment to Credit Agreement by and between TriSalus Operating Life Sciences, Inc., TriSalus Life Sciences, Inc. and OrbiMed Royalty & Credit Opportunities IV, LPForm 10-Q001-3981310.1May 15, 2025
10.24##Amendment No. 1 to Strategic Collaboration Agreement, dated March 2, 2021, by and between Surefire Medical Inc. d/b/a TriSalus Life Sciences and the University of Texas M.D. Anderson Cancer Center10-Q001-3981310.2May 15, 2025
10.25Securities Purchase Agreement dated April 30, 2025, by and among TriSalus Life Sciences, Inc. and the persons party thereto8-K001-3981310.1April 30, 2025
10.26Form of Registration Rights Agreement8-K001-3981310.2April 30, 2025
10.27Tender and Support Agreement, dated April 30, 2025, by and among TriSalus Life Sciences, Inc. and the persons party thereto8-K001-3981310.3April 30, 2025
10.28*Executive Employment Agreement by and between the Company and David Patience, dated May 27, 2025Form 10-Q001-3981310.1August 12, 2025
10.29*Sign-on Bonus Agreement by and between the Company and David Patience, dated May 27, 2025Form 10-Q001-3981310.2August 12, 2025
10.30*Consulting Agreement, by and between the Company and David Patience, dated June 2, 2025Form 10-Q001-3981310.3August 12, 2025
19.1TriSalus Life Sciences, Inc. Insider Trading PolicyForm 10-K001-3981319.1April 15, 2025
23.1Consent of Grant Thornton LLP, independent registered public accounting firm of TriSalus.
24.1Power of Attorney (see signature page).
Incorporated by Reference
ExhibitDescriptionSchedule/FormFile NumberExhibitsFiling Date
31.1 · Certification of the Principal Executive Officer pursuant to Rule 13a-14(a) and Rule 15d-14(a) under the Securities Exchange Act of 1934, as adopted pursuant to Section 302 of the Sarbanes-Oxley Act of 2002
31.2 · Certification of the Principal Financial Officer pursuant to Rule 13a-14(a) and Rule 15d-14(a) under the Securities Exchange Act of 1934, as adopted pursuant to Section 302 of the Sarbanes-Oxley Act of 2002
32.1@ · Certification of the Principal Executive Officer pursuant to 18 U.S.C. 1350, as adopted pursuant to Section 906 of the Sarbanes-Oxley Act of 2002
32.2@ · Certification of the Principal Financial Officer pursuant to 18 U.S.C. 1350, as adopted pursuant to Section 906 of the Sarbanes-Oxley Act of 2002
97.1TriSalus Life Sciences, Inc. Incentive Compensation Recoupment Policy.Form 10-K001-3981397.1April 11, 2024
101.INSInline XBRL Instance Document – the instance documents does not appear in the Interactive Data File as its XBRL tags are embedded within the Inline XBRL document.
101.CALInline XBRL Taxonomy Extension Calculation Linkbase Document.
101.SCHInline XBRL Taxonomy Extension Schema Document With Embedded Linkbase Documents.
101.DEFInline XBRL Taxonomy Extension Schema Document.
101.LABInline XBRL Taxonomy Extension Labels Linkbase Document.
101.PREInline XBRL Taxonomy Extension Presentation Linkbase Document.
104Cover Page (formatted as Inline XBRL and contained in Exhibit 101)

*Indicates management contract or compensatory plan or arrangement.

##Certain portions of this Exhibit have been omitted in accordance with Regulation S-K Item 601(b)(10)(iv) because they are not material and are the type of information that the Registrant treats as private or confidential. The Registrant agrees to furnish supplementally an unredacted copy of the Exhibit, or any section thereof, to the SEC upon request.

@The certifications attached as Exhibits 32.1 and 32.2 are not deemed filed with the Securities and Exchange Commission and are not to be incorporated by reference into any filing of the Registrant under the Securities Act of 1933, as amended, or the Securities Exchange Act of 1934, as amended (whether made before or after the date of this Form 10-K), irrespective of any general incorporation language contained in such filing.

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