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CRESCENT BIOPHARMA, INC.

For the period ended Dec 31, 2025. Filed Feb 26, 2026.

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A company's yearly report to the SEC, with audited financial statements. It is the fullest account a company gives of its business, its finances and the risks it sees.

FY2025 · Filed Feb 26, 2026

CBIO$13.92+2.0%Stored close · as of Nov 10, 2026

Extracted filing text, with the paragraph anchors used by the comparison.

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Contents

Item 8. Consolidated Statements of Cash Flows

CONSOLIDATED STATEMENTS OF CASH FLOWS

(in thousands)

Twelve Months EndedDecember 31, 2025Period from September 19, 2024 (Inception) Through December 31, 2024
Cash flows from operating activities:
Net loss$(153,942)$(17,867)
Adjustments to reconcile net loss to net cash used in operating activities:
Share-based compensation expense(1)13,3001,134
Research and development license expense80,000—
Depreciation expense84—
Non-cash interest expense(2)2,1852
Non-cash research and development expense related to Paragon option agreement—1,000
Non-cash lease expense212—
Changes in operating assets and liabilities:
Accounts payable2,081107
Accrued expenses and other current liabilities(3)5,3632,172
Related party accounts payable and other current liabilities(7,081)7,221
Deferred revenue4,156—
Deposit liability5,000—
Operating lease liability(37)—
Accounts receivable(18,000)—
Prepaid expenses and other current assets(5,015)(38)
Other assets162—
Net cash used in operating activities(71,532)(6,269)
Cash flows from investing activities:
Purchase of research and development license(72,000)—
Purchases of property and equipment(919)—
Net cash used in investing activities(72,919)—
Cash flows from financing activities:
Proceeds from the Pre-Closing Financing, net143,007—
Proceeds from the private placement financing, net178,880—
Cash acquired in connection with the reverse recapitalization1,269—
Proceeds from early exercise of options5—
Proceeds from issuance of common stock—315
Proceeds from issuance of Series Seed convertible preferred stock—4,000
Proceeds from the issuance of notes payable, net of issuance costs(4)—37,480
Payment of deferred offering costs—(760)
Repurchase of equity awards(177)—
Net cash provided by financing activities322,98441,035
Net increase in cash, cash equivalents, and restricted cash178,53334,766
Cash at beginning of period34,766—
Cash, cash equivalents, and restricted cash at end of period$213,299$34,766
Supplemental disclosure of non-cash operating and financing activities:
Operating lease liability arising from obtaining operating right-of-use asset$1,681$—
Assets acquired in connection with the reverse recapitalization$1,710$—
Other liabilities assumed in connection with the reverse recapitalization$(2,454)$—
Purchases of property and equipment included in accounts payable and accrued expenses$11$—
Deferred financing costs included in accounts payable and accrued expenses$6,945$53
Convertible note principal and non-cash accrued interest converted to ordinary shares$40,515$—
Non-cash exchange of Pre-Merger Crescent Series Seed Preferred Stock for Series A Non-Voting Convertible Preferred Shares$4,000$—

(1)Includes related party amounts of $4,297 for the twelve months ended December 31, 2025 and $61 for the period from September 19, 2024 (inception) through December 31, 2024.

(2)Includes related party amounts of $865 for the twelve months ended December 31, 2025 and $0 for the period from September 19, 2024 (inception) through December 31, 2024.

(3)Includes related party amounts of $0 for the twelve months ended December 31, 2025 and $341 for the period from September 19, 2024 (inception) through December 31, 2024.

(4)Includes related party amounts of $0 for the twelve months ended December 31, 2025 and $14,993 for the period from September 19, 2024 (inception) through December 31, 2024

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The text of this filing, as the company filed it with the SEC, without its images or exhibits. This is not investment advice.