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CRESCENT BIOPHARMA, INC.

For the period ended Dec 31, 2025. Filed Feb 26, 2026.

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A company's yearly report to the SEC, with audited financial statements. It is the fullest account a company gives of its business, its finances and the risks it sees.

FY2025 · Filed Feb 26, 2026

CBIO$13.92+2.0%Stored close · as of Nov 10, 2026

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Contents

Consolidated Statements of Operations and omprehensive Loss

CONSOLIDATED STATEMENT OF OPERATIONS AND COMPREHENSIVE LOSS

(in thousands, except share and per share amounts)

Twelve Months Ended December 31, 2025Period from September 19, 2024 (Inception) Through December 31, 2024
License revenue$10,844$—
Operating expenses
Research and development(1)138,08614,034
General and administrative(2)25,3903,157
Total operating expenses163,47617,191
Loss from operations(152,632)(17,191)
Other income (expense):
Interest income2,875176
Interest expense(3)(2,185)(852)
Loss before provision for income taxes(151,942)(17,867)
Provision for income taxes(2,000)—
Net loss and comprehensive loss$(153,942)$(17,867)
Net loss per share attributable to ordinary shareholders, basic and diluted$(12.81)$(23.28)
Net loss per share attributable to Series A non-voting convertible preferred shareholders, basic and diluted$(12,818.01)—
Weighted-average ordinary shares outstanding used in computing net loss per share to ordinary shareholders, basic and diluted10,413,649767,580
Weighted-average Series A non-voting convertible preferred shares outstanding used in computing net loss per share to Series A non-voting convertible preferred shareholders, basic and diluted1,599—

(1)Includes related party amount of $23,653 for the twelve months ended months ended December 31, 2025 and $13,185 for the period from September 19, 2024 (inception) through December 31, 2024.

(2)Includes related party amount of $720 for the twelve months ended months ended December 31, 2025 and $571 for the period from September 19, 2024 (inception) through December 31, 2024.

(3)Includes related party amount of $865 for the twelve months ended December 31, 2025 and $341 for the period from September 19, 2024 (inception) through December 31, 2024.

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The text of this filing, as the company filed it with the SEC, without its images or exhibits. This is not investment advice.