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BeOne Medicines Ltd.

For the period ended Dec 31, 2025. Filed Feb 26, 2026.

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A company's yearly report to the SEC, with audited financial statements. It is the fullest account a company gives of its business, its finances and the risks it sees.

FY2025 · Filed Feb 26, 2026

ONC$424.00+1.6%Stored close · as of Nov 10, 2026

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Contents

Item 15. Exhibits and Financial Statement Schedules

The financial statements listed in the Index to Consolidated Financial Statements beginning on page 141 are filed as part of this Annual Report.

We have included Additional Financial Information of Parent Company - Financial Statements Schedule I for the years ended December 31, 2025, 2024 and 2023 on page 201. No other financial statement schedules have been filed as part of this report because they are not applicable, not required or the information required is shown in the financial statements or the notes thereto.

The exhibits filed as part of this Annual Report are set forth on the Exhibit Index immediately following our consolidated financial statements. The Exhibit Index is incorporated herein by reference.

Schedule I - Condensed Financial Information of Registrant

Condensed Statements of Operations

Year Ended December 31,
202520242023
$$$
Operating expenses
Research and development29,372427,129381,854
Amortization of research and development cost share liability(101,095)(73,226)(55,294)
Selling, general and administrative69,530357,103304,543
Total operating expenses(2,193)711,006631,103
Income (loss) from operations2,193(711,006)(631,103)
Interest (expense) income, net(20,887)3,10148,982
Other income (expense), net305,68663,522(297,856)
Income (loss) before income taxes286,992(644,383)(879,977)
Income tax expense594031,731
Net income (loss)286,933(644,786)(881,708)

Condensed Statements of Comprehensive Loss

Year Ended December 31,
202520242023
$$$
Net income (loss)286,933(644,786)(881,708)
Other comprehensive (loss) income, net of tax of nil:
Foreign currency translation adjustments69,300(47,565)(25,464)
Other adjustments1,504(1,977)3,435
Comprehensive income (loss)357,737(694,328)(903,737)

Condensed Balance Sheets

As of December 31,
20252024
$$
Assets
Current assets:
Cash and cash equivalents584,216400,135
Prepaid expenses and other current assets180,495249,016
Total current assets764,711649,151
Loans to subsidiaries1,710,7371,731,266
Investment in wholly owned subsidiaries3,314,1622,081,335
Other non-current assets41,658114,728
Total assets5,831,2684,576,480
Liabilities and shareholders’ equity
Current liabilities:
Accrued expenses and other payables254,815312,957
Indebtedness to subsidiaries253,194—
Research and development cost share liability, current portion64,345111,154
Short-term debt9,063762,146
Total current liabilities581,4171,186,257
Long-term debt836,369—
Research and development cost share liability, non-current portion—54,286
Other long-term liabilities52,2883,714
Total liabilities1,470,0741,244,257
Total shareholders’ equity4,361,1943,332,223
Total liabilities and shareholders’ equity5,831,2684,576,480

Condensed Statements of Cash Flows

Year Ended December 31,
202520242023
$$$
Cash flows from operating activities:
Net income (loss)286,933(644,786)(881,708)
Adjustments to reconcile net income (loss) to net cash used in operating activities:
Acquired in-process research and development——15,000
Amortization of research and development cost share liability(101,095)(73,226)(55,294)
Unrealized (gains) losses in subsidiaries(484,466)(85,471)237,351
Other items, net81,24731,651(374,370)
Changes in operating assets and liabilities:
Prepaid expenses and other assets27,5441,05330,519
Accrued expenses and other payables56,259627,307(140,126)
Net cash used in operating activities(133,578)(143,472)(1,168,628)
Cash flows from investing activities:
Proceeds from sale or maturity of short-term investments9542,628552,000
Loans to subsidiaries—(442,917)(53,100)
Repayments from subsidiaries279,031423,532252,662
Investment in subsidiaries(173,429)(406,624)(883,328)
Other investing activities(9,670)(17,735)(27,981)
Net cash provided by (used in) investing activities96,886(441,116)(159,747)
Cash flows from financing activities:
Proceeds from long-term loan850,586——
Proceeds from short-term loans139,453813,058547,842
Repayment of short-term loans(893,987)(593,898)(293,002)
Proceeds from option exercises and employee share purchase plan196,28145,37155,712
Other financing activities(47,587)——
Net cash provided by financing activities244,746264,531310,552
Effect of foreign exchange rate changes, net6,228(4,356)—
Net increase (decrease) in cash, cash equivalents, and restricted cash214,282(324,413)(1,017,823)
Cash, cash equivalents, and restricted cash, beginning of year400,135724,5481,742,371
Cash, cash equivalents, and restricted cash, end of year614,417400,135724,548

Notes

  1. Schedule I has been provided pursuant to the requirements of Rules 12-04(a) and 5-04(c) of Regulation S-X (the “Rules”), which require condensed financial information as to the financial position, changes in financial position and results of operations of a parent company as of the same dates and for the same periods for which audited consolidated financial statements have been presented when the restricted net assets of consolidated subsidiaries exceed 25 percent of consolidated net assets as of the end of the most recently completed fiscal year.

  2. The condensed financial information has been prepared using the same accounting policies as set out in the consolidated financial statements. For purposes of this condensed financial information, BeOne Medicines Ltd. (the “Parent Company”)’s investments in its wholly owned and majority owned subsidiaries are recorded under the equity method of accounting in accordance with ASC 323.

  3. Certain information and footnote disclosures normally included in financial statements prepared in accordance with U.S. GAAP have been condensed or omitted as allowed under the Rules. These footnote disclosures provide certain supplemental information relating to the operations of the Company and, as such, these statements should be read in conjunction with the notes to the consolidated financial statements.

  4. As of December 31, 2025, the Parent Company had a remaining capital commitment of $4,350 on an equity investment which is expected to be paid from time to time over the investment period. The Parent Company has unconditionally guaranteed the payment and performance of the obligations of BeOne Medicines I GmbH in accordance with the terms of the global strategic oncology collaboration with Amgen Inc. No amounts have been recognized related to this guarantee. The Parent Company has no other material contingencies, long-term obligations or guarantees not already disclosed in its consolidated financial statements.

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