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Protagonist Therapeutics, Inc

For the period ended Jun 30, 2025. Filed Aug 6, 2025.

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About this filing

A company's report for each of its first three quarters. The financial statements are not audited. It shows how the business has moved since the last annual report, and what management says changed.

Jun 30, 2025 · Filed Aug 6, 2025

PTGX$136.26+0.3%Stored close · as of Nov 10, 2026

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Condensed Consolidated Statements of Cash Flows

(In thousands)

​​​​​​​
​ · ​ · Six Months Ended
​ · ​ · June 30,
​ · 2025 · 2024
Cash Flows from Operating Activities · ​ · ​ · ​
Net (loss) income​$(46,426)​$176,724
Adjustments to reconcile net (loss) income to net cash provided by operating activities:​​​​​​
Stock-based compensation​​24,714​​18,296
Non-cash lease expense​​1,137​​1,235
Depreciation​​543​​477
Accretion of discount on marketable securities​​(4,203)​​(3,277)
Net realized loss on sale of marketable securities​​5​​—
Changes in operating assets and liabilities:​​​​​​
Receivable from collaboration partner​​165,000​​9,957
Contract asset​​(22,287)​​—
Prepaid expenses and other assets​​(2,045)​​(2,925)
Accounts payable​​1,612​​2,627
Accrued expenses and other payables​​(8,378)​​(4,229)
Payable to collaboration partner​​—​​(3)
Income taxes payable​​(2,689)​​2,650
Deferred revenue​​(10,504)​​40,880
Operating lease liability​​104​​(1,219)
Net cash provided by operating activities​​96,583​​241,193
Cash Flows from Investing Activities​​​​​​
Purchase of marketable securities​​(281,194)​​(240,627)
Proceeds from maturities of marketable securities​​235,957​​158,849
Proceeds from sale of marketable securities​​7,003​​—
Purchases of property and equipment​​(1,358)​​(270)
Net cash used in investing activities​​(39,592)​​(82,048)
Cash Flows from Financing Activities​​​​​​
Proceeds from issuance of common stock upon exercise of stock options and purchases under employee stock purchase plan​​14,847​​10,371
Tax withholding payments related to net settlement of restricted stock units​​(479)​​(600)
Net cash provided by financing activities​​14,368​​9,771
Net increase in cash, cash equivalents and restricted cash​​71,359​​168,916
Cash, cash equivalents and restricted cash, beginning of period​97,474​186,952
Cash, cash equivalents and restricted cash, end of period​$168,833​$355,868
Supplemental Disclosure of Non-Cash Financing and Investing Information:​​​​​​
Purchases of property and equipment in accounts payable and accrued liabilities​$103​$275
Right-of-use asset obtained in exchange for lease obligation​$—​$10,511
Leasehold improvements obtained under tenant improvement allowance​$—​$516
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The text of this filing, as the company filed it with the SEC, without its images or exhibits. This is not investment advice.