MeiraGTx Holdings plc
For the period ended Dec 31, 2024. Filed Mar 13, 2025.
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A company's yearly report to the SEC, with audited financial statements. It is the fullest account a company gives of its business, its finances and the risks it sees.
FY2024 · Filed Mar 13, 2025
MGTX$9.62+1.4%Stored close · as of Nov 10, 2026
Extracted filing text, with the paragraph anchors used by the comparison.
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Item 15. Exhibits and Financial Statement Schedules
EXHIBIT INDEX
| · · · · · · · | ||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Exhibit Number · · Exhibit Description · · Incorporated by Reference | ||||||||||||
| · · Form · File No. · Exhibit · FilingDate · Filed/FurnishedHerewith | ||||||||||||
| 3.1 | | Amended and Restated Memorandum and Articles of Association of the Registrant. | | 10-Q | | 001-38520 | | 3.1 | | 8/7/19 | | |
| 4.1 | | Specimen Share Certificate evidencing the ordinary shares of the Registrant. | | S-1 | | 333-224914 | | 4.1 | | 5/29/18 | | |
| 4.2 | | Shareholder Agreement. | | 10-K | | 001-38520 | | 4.2 | | 3/11/20 | | |
| 4.3 | | Description of Securities. | | 10-K | | 001-38520 | | 4.3 | | 3/11/20 | | |
| 4.4 | | Form of Warrant Agreement, dated August 2, 2022, issued by MeiraGTx Holdings plc to certain warrant holders. | | 10-Q | | 001-38520 | | 4.1 | | 11/10/22 | | |
| 10.1# | | 2016 Equity Incentive Plan, as amended, and form of option agreements thereunder. | | S-1/A | | 333-224914 | | 10.1 | | 5/29/18 | | |
| 10.2# | | 2018 Incentive Award Plan and forms of award agreements thereunder. | | S-1/A | | 333-224914 | | 10.2 | | 5/29/18 | | |
| 10.3# | | Non-Employee Director Compensation Program. | | 10-Q | | 001-38520 | | 10.1 | | 08/12/24 | | |
| 10.4# | | Form of Indemnification Agreement for Directors and Officers. | | S-1/A | | 333-224914 | | 10.4 | | 5/29/18 | | |
| 10.5 | | License and Sub-Lease Agreement, dated May 31, 2019, between MeiraGTx LLC and Imclone Systems, LLC. | | 10-Q | | 001-38520 | | 10.2 | | 8/7/19 | | |
| 10.6 | | Lease Agreement, effective February 2, 2016, among MeiraGTx Limited, Moorfields Eye Hospital NHS, Foundation Trust and Kadmon Corporation LLC. | | S-1 | | 333-224914 | | 10.6 | | 5/14/18 | | |
| 10.7# | | Employment Agreement, dated February 15, 2016, between MeiraGTx Limited and Alexandria Forbes, Ph.D., as amended. | | S-1/A | | 333-224914 | | 10.7 | | 5/29/18 | | |
| 10.8# | | Employment Agreement, dated February 15, 2016 between MeiraGTx Limited and Richard Giroux, as amended. | | S-1/A | | 333-224914 | | 10.8 | | 5/29/18 | | |
| 10.9# | | Employment Agreement, dated April 27, 2015, between MeiraGTx Limited and Stuart Naylor, Ph.D., as amended. | | S-1/A | | 333-224914 | | 10.9 | | 5/29/18 | | |
| 10.10† | | Agreement and Plan of Merger, dated December 31, 2015, among MeiraGTx Acquisition Corporation, BRI-Alzan, Inc., F-Prime Inc., Gregory Petsko, Dagmar Ringe, Brandeis University and MeiraGTx Limited. | | S-1/A | | 333-224914 | | 10.14 | | 5/29/18 | | |
| 10.11# | | 2018 Employee Share Purchase Plan. | | S-1/A | | 333-224914 | | 10.15 | | 5/29/18 | | |
| · · · · · · · | ||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Exhibit Number · · Exhibit Description · · Incorporated by Reference | ||||||||||||
| · · Form · File No. · Exhibit · FilingDate · Filed/FurnishedHerewith | ||||||||||||
| 10.12# | | UK Sub-Plan Under the 2018 Incentive Award Plan. | | 10-K | | 001-38520 | | 10.12 | | 3/26/19 | | |
| 10.13# | | Form of Option Grant Notice and Option Agreement Under the UK Sub-Plan to the 2018 Incentive Award Plan. | | 10-K | | 001-38520 | | 10.13 | | 3/26/19 | | |
| 10.14# | | Form of Change in Control Agreement. | | 10-K | | 001-38520 | | 10.14 | | 3/11/21 | | |
| 10.15 | | Lease agreement by and between Moorfields Eye Hospital NHS Foundation Trust and MeiraGTx UK II Limited, dated July 30, 2018. | | 10-Q | | 001-38520 | | 10.4 | | 8/8/18 | | |
| 10.16 | | Lease agreement by and between Moorfields Eye Hospital NHS Foundation Trust and MeiraGTx UK II Limited, dated July 30, 2018. | | 10-Q | | 001-38520 | | 10.5 | | 8/8/18 | | |
| 10.17 | | Transfer of Title, dated December 14, 2018, and Lease, dated October 12, 2001, relating to the Pharmacy Manufacturing Unit, Britannia Walk, London, England. | | 8-K | | 001-38520 | | 10.1 | | 12/14/18 | | |
| 10.18 | | Overage Deed, dated December 14, 2018, between Moorfields Eye Hospital NHS Foundation Trust and MeiraGTx UK II Limited relating to the Pharmacy Manufacturing Unit, Britannia Walk, London, England. | | 8-K | | 001-38520 | | 10.2 | | 12/14/18 | | |
| 10.19† | | Consulting Agreement, dated October 5, 2018, between MeiraGTx Holdings plc, Vector Consulting LLC, Michael G. Kaplitt, Matthew During, and Stephen B. Kaplitt. | | 10-K | | 001-38520 | | 10.19 | | 3/26/19 | | |
| 10.20† | | License Agreement (RPE65), dated January 29, 2019, as amended and restated by and among UCL Business Plc, MeiraGTx UK II Limited and MeiraGTx Limited. | | 10-K | | 001-38520 | | 10.20 | | 3/26/19 | | |
| 10.21† | | License Agreement (CNGB3), dated January 29, 2019, as amended and restated by and among UCL Business Plc, MeiraGTx Holdings plc, MeiraGTx UK II Limited and MeiraGTx Limited. | | 10-K | | 001-38520 | | 10.21 | | 3/26/19 | | |
| 10.22† | | License Agreement (CNGA3), dated January 29, 2019, as amended and restated by and among UCL Business Plc, MeiraGTx UK II Limited and MeiraGTx Limited. | | 10-K | | 001-38520 | | 10.22 | | 3/26/19 | | |
| 10.23† | | Amendment No. 4 to Exclusive License Agreement, dated January 29, 2019, between UCLB and MeiraGTx Limited. | | 10-K | | 001-38520 | | 10.24 | | 3/26/19 | | |
| 10.24†† | | Collaboration, Option and License Agreement, dated January 30, 2019, by and among Janssen Pharmaceuticals, Inc., MeiraGTx UK II Limited and MeiraGTx Holdings plc. | | | | | | | | | | * |
| 10.25†† | | First Amendment to Collaboration, Option and License Agreement, dated December 16, 2021. | | 10-K | | 001-3852 | | 10.26 | | 3/10/22 | | |
| · · · · · · · | ||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Exhibit Number · · Exhibit Description · · Incorporated by Reference | ||||||||||||
| · · Form · File No. · Exhibit · FilingDate · Filed/FurnishedHerewith | ||||||||||||
| 10.26 | | Registration Rights Agreement, dated February 26, 2019, by and among MeiraGTx Holdings plc and the investors named therein. | | 8-K | | 001-38520 | | 10.2 | | 2/26/19 | | |
| 10.27 | | Agreement for Lease with Landlord’s Refurbishment Works, dated May 29, 2019, between MeiraGTx UK II Limited and Provost 1 Limited and Provost 2 Limited, including agreed form of Lease between MeiraGTx UK II Limited and Provost 1 Limited and Provost 2 Limited. | | 10-Q | | 001-38520 | | 10.3 | | 8/7/19 | | |
| 10.28# | | Form of Restricted Share Unit Grant Notice and Restricted Share Unit Agreement Under the 2018 Incentive Award Plan. | | 10-K | | 001-38520 | | 10.30 | | 3/11/20 | | |
| 10.29# | | Form of Restricted Share Unit Grant Notice and Restricted Share Unit Agreement Under the UK Sub-Plan to the 2018 Incentive Award Plan. | | 10-K | | 001-38520 | | 10.31 | | 3/11/20 | | |
| 10.30 | | Particulars and Conditions of Sale of Building 2, Block K, Shannon Free Zone, Shannon, County Clare, Ireland, dated as of August 4, 2020, by and between Shannon Commercial Enterprises DAC trading as Shannon Commercial Properties and MeiraGTx Ireland DAC, including agreed form of Lease between Shannon Commercial Enterprises DAC and MeiraGTx Ireland DAC. | | 10-Q | | 001-38520 | | 10.1 | | 11/5/20 | | |
| 10.31 | | Particulars and Conditions of Sale of Building 3, Block K, Shannon Free Zone, Shannon, County Clare, Ireland, dated as of August 4, 2020, by and between Shannon Commercial Enterprises DAC trading as Shannon Commercial Properties and MeiraGTx Ireland DAC, including agreed form of Lease between Shannon Commercial Enterprises DAC and MeiraGTx Ireland DAC. | | 10-Q | | 001-38520 | | 10.2 | | 11/5/20 | | |
| 10.32# | | Deferred Compensation Plan for Non-Employee Directors. | | 10-K | | 001-38520 | | 10.35 | | 3/10/22 | | |
| 10.33# | | Form of Restricted Share Unit Grant Notice and Restricted Share Unit Agreement for Non-Employee Directors Under the 2018 Incentive Award Plan. | | 10-K | | 001-38520 | | 10.36 | | 3/10/22 | | |
| 10.34†† | | Credit Agreement and Guaranty, dated August 2, 2022, by and among MeiraGTx Holdings plc, as borrower, MeiraGTx UK II Limited and MeiraGTx Ireland DAC, as guarantors, the lenders and other parties from time to time party thereto and Perceptive Credit Holdings III, LP, as administrative agent and lender. | | 10-Q | | 001-38520 | | 10.1 | | 11/10/22 | | |
| · · · · · · · | ||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Exhibit Number · · Exhibit Description · · Incorporated by Reference | ||||||||||||
| · · Form · File No. · Exhibit · FilingDate · Filed/FurnishedHerewith | ||||||||||||
| 10.35 | | Amendment No. 1 to Credit Agreement and Guaranty, dated December 19, 2022, by and among MeiraGTx Holdings plc, as borrower, certain subsidiary guarantors and lenders party thereto, and Perceptive Credit Holdings III, LP, as administrative agent. | | 10-K | | 001-38520 | | 10.36 | | 3/14/23 | | |
| 10.36†† | | Amended and Restated Notes Purchase Agreement and Guaranty, dated December 19, 2022, by and among MeiraGTx Holdings plc, as issuer, the subsidiary guarantors and noteholders from time to time party thereto, and Perceptive Credit Holdings III, LP, as administrative agent. | | 10-K | | 001-38520 | | 10.37 | | 3/14/23 | | |
| 10.37 | | Tranche 1 Note, dated December 19, 2022, by and among MeiraGTx Holdings plc, as issuer, the subsidiaries guarantors and noteholders from time to time party thereto, and Perceptive Credit Holdings III, LP, as administrative agent. | | 10-K | | 001-38520 | | 10.38 | | 3/14/23 | | |
| 10.38 | | Consent and Amendment to Amended and Restated Notes Purchase Agreement and Guaranty, dated August 10, 2023, by and among MeiraGTx Holdings plc, as issuer, the subsidiary guarantors and noteholders from time to time party thereto, and Perceptive Credit Holdings III, LP, as administrative agent and noteholder. | | 8-K | | 001-38520 | | 10.1 | | 8/10/23 | | |
| 10.39 | | Consent and Amendment to Amended and Restated Notes Purchase Agreement and Guaranty, dated December 20, 2023, by and among MeiraGTx Holdings plc, as issuer, the subsidiary guarantors and noteholders from time to time party thereto, and Perceptive Credit Holdings III, LP, as administrative agent and noteholder. | | 10-K | | 001-38520 | | 10.39 | | 3/15/24 | | |
| 10.40 | | Securities Purchase Agreement, dated November 9, 2022, by and among MeiraGTx Holdings plc and Johnson & Johnson Innovation – JJDC, Inc. | | 10-K | | 001-38520 | | 10.39 | | 3/14/23 | | |
| 10.41 | | Registration Rights Agreement, dated November 15, 2022, by and among MeiraGTx Holdings plc and Johnson & Johnson Innovation – JJDC, Inc. | | 10-K | | 001-38520 | | 10.40 | | 3/14/23 | | |
| 10.42 | | First Amendment to Registration Rights Agreement, dated May 12, 2023, by and among MeiraGTx Holdings plc and Johnson & Johnson Innovation – JJDC, Inc. | | 10-Q | | 001-38520 | | 10.3 | | 8/10/23 | | |
| 10.43 | | Securities Purchase Agreement, dated May 3, 2023, by and among MeiraGTx Holdings plc and the Investors named therein. | | S-3 | | 333-273672 | | 10.1 | | 8/3/23 | | |
| 10.44 | | Registration Rights Agreement, dated May 5, 2023, by and among MeiraGTx Holdings plc and the Investors named therein. | | S-3 | | 333-273672 | | 10.2 | | 8/3/23 | | |
| · · · · · · · | ||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Exhibit Number · · Exhibit Description · · Incorporated by Reference | ||||||||||||
| · · Form · File No. · Exhibit · FilingDate · Filed/FurnishedHerewith | ||||||||||||
| 10.45 | | Investment Agreement, dated October 30, 2023, by and among MeiraGTx Holdings plc, Sanofi Foreign Participations B.V. and Sanofi. | | 8-K | | 001-38520 | | 10.1 | | 10/30/23 | | |
| 10.46 | | Registration Rights Agreement, dated October 30, 2023, by and between MeiraGTx Holdings plc and Sanofi Foreign Participations B.V. | | 8-K | | 001-38520 | | 10.2 | | 10/30/23 | | |
| 10.47†† | | Asset Purchase Agreement, dated December 20, 2023, by and among Janssen Pharmaceuticals, Inc., MeiraGTx UK II Limited and MeiraGTx Holdings plc. | | 10-K | | 001-38520 | | 10.47 | | 3/15/24 | | |
| 10.48†† | | Termination Agreement, dated December 20, 2023, by and among Janssen Pharmaceuticals, Inc., MeiraGTx UK II Limited and MeiraGTx Holdings plc. | | 10-K | | 001-38520 | | 10.48 | | 3/15/24 | | |
| 10.49†† | | Framework Agreement, dated March 9, 2025, by and among Hologen Limited, Hologen Neuro AI Limited, MeiraGTx Neuro UK Limited and MeiraGTx Holdings plc. | | | | | | | | | | * |
| 10.50†† | | Form of Collaboration and License Agreement by and among Hologen Neuro AI Ltd, Hologen Neuro AI UK Limited, Hologen Limited, MeiraGTx Holdings plc, MeiraGTx UK Neuro Limited and MeiraGTx Neuro I, LLC. | | | | | | | | | | * |
| 10.51†† | | Framework Agreement, dated March 9, 2025, by and among MeiraGTx Manufacturing Limited, MeiraGTx Limited and Hologen Limited. | | | | | | | | | | * |
| 19.1 | | MeiraGTx Holdings plc Insider Trading Compliance Policy. | | | | | | | | | | * |
| 21 | | List of Subsidiaries. | | | | | | | | | | * |
| 23.1 | | Consent of Ernst & Young LLP. | | | | | | | | | | * |
| 31.1 | | Certification of Chief Executive Officer pursuant to Rules 13a-14(a)/15d-14(a) under the Securities Exchange Act of 1934, as amended. | | | | | | | | | * | |
| 31.2 | | Certification of Chief Financial Officer pursuant to Rules 13a-14(a)/15d-14(a) under the Securities Exchange Act of 1934, as amended. | | | | | | | | | * | |
| 32.1 | | Certification of Chief Executive Officer pursuant to 18 U.S.C. Section 1350, as adopted pursuant to Section 906 of the Sarbanes-Oxley Act of 2002. | | | | | | | | | ** | |
| · · · · · · · | ||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Exhibit Number · · Exhibit Description · · Incorporated by Reference | ||||||||||||
| · · Form · File No. · Exhibit · FilingDate · Filed/FurnishedHerewith | ||||||||||||
| 32.2 · · Certification of Chief Financial Officer pursuant to 18 U.S.C. Section 1350, as adopted pursuant to Section 906 of the Sarbanes-Oxley Act of 2002. · · · · · · · · · ** | ||||||||||||
| 97.1 | | Policy for Recovery of Erroneously Awarded Compensation. | | 10-K | | 001-38520 | | 97.1 | | 3/15/24 | | |
| 101.INS | | Inline XBRL Instance Document. | | | | | | | | | | * |
| 101.SCH | | Inline XBRL Taxonomy Extension Schema Document. | | | | | | | | | | * |
| 101.CAL | | Inline XBRL Taxonomy Extension Calculation Linkbase Document. | | | | | | | | | | * |
| 101.DEF | | Inline XBRL Taxonomy Definition Linkbase Document. | | | | | | | | | | * |
| 101.LAB | | Inline XBRL Taxonomy Label Linkbase Document. | | | | | | | | | | * |
| 101.PRE | | Inline XBRL Taxonomy Extension Presentation Linkbase Document. | | | | | | | | | | * |
| 104 | | Cover Page Interactive Data File (formatted as Inline XBRL and contained in Exhibit 101). | | | | | | | | | | * |
- Filed herewith
** Furnished herewith
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