Protagonist Therapeutics Inc
For the period ended Dec 31, 2024. Filed Feb 21, 2025.
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FY2024 · Filed Feb 21, 2025
PTGX$136.26+0.3%Stored close · as of Nov 10, 2026
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Item 8. Consolidated Statements of Cash Flows
Consolidated Statements of Cash Flows
(In thousands)
| | | | | | | | | | |
|---|---|---|---|---|---|---|---|---|---|
| · · Year Ended December 31, | |||||||||
| · 2024 · 2023 · 2022 | |||||||||
| Cash Flows from Operating Activities · · · · | |||||||||
| Net income (loss) | | $275,188 | | $(78,955) | | $(127,393) | |||
| Adjustments to reconcile net income (loss) to net cash provided by (used in) operating activities: | | | | | | | | | |
| Stock-based compensation | | | 37,554 | | | 29,293 | | | 24,202 |
| Operating lease right-of-use asset amortization | | | 2,069 | | | 2,335 | | | 2,335 |
| Depreciation | | | 826 | | | 977 | | | 1,034 |
| Accretion of discount on marketable securities | | | (8,875) | | | (4,569) | | | (549) |
| Other | | | — | | | 194 | | | — |
| Changes in operating assets and liabilities: | | | | | | | | | |
| Receivable from collaboration partner | | | (155,000) | | | (9,990) | | | 1,556 |
| Prepaid expenses and other assets | | | (3,768) | | | 1,753 | | | 3,754 |
| Research and development tax incentive receivable | | | — | | | — | | | 2,686 |
| Accounts payable | | | 842 | | | (2,868) | | | 2,045 |
| Payable to collaboration partner | | | (3) | | | (66) | | | (830) |
| Accrued expenses and other payables | | | 4,289 | | | (5,597) | | | (12,715) |
| Deferred revenue | | | 30,567 | | | — | | | (1,601) |
| Income taxes payable | | | 2,689 | | | — | | | — |
| Operating lease liability | | | (2,226) | | | (2,743) | | | (2,661) |
| Net cash provided by (used in) operating activities | | | 184,152 | | | (70,236) | | | (108,137) |
| Cash Flows from Investing Activities | | | | | | | | | |
| Purchase of marketable securities | | | (621,702) | | | (191,045) | | | (214,874) |
| Proceeds from maturities of marketable securities | | | 323,574 | | | 152,396 | | | 307,137 |
| Purchases of property and equipment | | | (1,355) | | | (609) | | | (795) |
| Net cash (used in) provided by investing activities | | | (299,483) | | | (39,258) | | | 91,468 |
| Cash Flows from Financing Activities | | | | | | | | | |
| Proceeds from issuance of common stock upon exercise of stock options and purchases under employee stock purchase plan | | | 26,453 | | | 4,774 | | | 4,448 |
| Tax withholding payments related to net settlement of restricted stock units | | | (600) | | | (769) | | | (188) |
| Proceeds from public offering of common stock, net of issuance costs | | | — | | | 107,798 | | | — |
| Proceeds from at-the-market offering, net of issuance costs | | | — | | | 24,302 | | | 14,553 |
| Proceeds from exercise of Warrants in exchange for issuance of Pre-Funded Warrants | | | — | | | 33,813 | | | — |
| Proceeds from issuance of common stock upon exercise of Warrants | | | — | | | 559 | | | — |
| Issuance costs related to prior period common stock offering | | | — | | | — | | | 25 |
| Net cash provided by financing activities | | | 25,853 | | | 170,477 | | | 18,838 |
| Effect of exchange rate changes on cash, cash equivalents and restricted cash | | | — | | | — | | | (90) |
| Net (decrease) increase in cash, cash equivalents and restricted cash | | | (89,478) | | | 60,983 | | | 2,079 |
| Cash, cash equivalents and restricted cash, beginning of period | | 186,952 | | 125,969 | | 123,890 | |||
| Cash, cash equivalents and restricted cash, end of period | | $97,474 | | $186,952 | | $125,969 | |||
| Supplemental Disclosure of Cash Flow Information: | | | | | | | | | |
| Cash paid for taxes | | $1,530 | | $— | | $— | |||
| Supplemental Disclosure of Non-Cash Financing and Investing Information: | | | | | | | | | |
| Right-of-use asset obtained in exchange for lease obligation | | $10,511 | | $— | | $— | |||
| Leasehold improvements obtained under tenant improvement allowance | | $1,421 | | $— | | $— | |||
| Purchases of property and equipment in accounts payable and accrued liabilities | | $46 | | $61 | | $19 | |||
P****ROTAGONIST THERAPEUTICS, INC.
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