Corvus Pharmaceuticals Inc

Rule 10b5-1 Trading Arrangements

During the quarter ended June 30, 2024, none of our directors or officers (as defined in Rule 16a-1(f) under the Securities Exchange Act of 1934, as amended)adopted, modified orterminated a “Rule 10b5-1 trading arrangement” or a “non-Rule 10b5-1 trading arrangement”, as each term is defined in Item 408(a) of Regulation S-K.

Termination of 2023 Sales Agreement

On March 28, 2023, we entered into an open market sale agreement (the “2023 Sales Agreement”) with Jefferies LLC (“Jefferies”) to sell shares of our common stock, par value $0.0001 per share (the “Common Stock”) from time-to-time, with aggregate gross sales proceeds of up to $90.0 million, through Jefferies as our sales agent. On May 1, 2024, we amended the 2023 Sales Agreement to decrease the aggregate gross sales proceeds that may be sold pursuant to the 2023 Sales Agreement from $90.0 million to $8.2 million, which decreased the amount available for sale to $100,000. On August 6, 2024, we terminated the 2023 Sales Agreement effective immediately.

Jefferies Sales Agreement

On August [6], 2024 we entered into an open market sale agreement (the “2024 Sales Agreement”) with Jefferies to sell Common Stock, from time to time, with aggregate gross sales proceeds of up to $100.0 million, through an at-the-market equity offering program (the “ATM Program”) with Jefferies as our sales agent.

Jefferies may sell the Common Stock by any method that is deemed to be an “at-the-market offering” as defined in Rule 415 of the Securities Act of 1933, as amended, including sales made directly on the Nasdaq Global Market (“Nasdaq”) or any other trading market for the Common Stock. Jefferies will use commercially reasonable efforts, consistent with its normal sales and trading practices and applicable state and federal laws, rules and regulations and the rules of Nasdaq, to sell the Common Stock from time to time, based upon instructions from us (including any price, time or size limits or other customary parameters or conditions the Company may impose). We will pay Jefferies a

commission of up to 3.0% of the gross sales proceeds of any Common Stock sold through Jefferies under the 2024 Sales Agreement and have provided Jefferies with customary indemnification rights.

We are not obligated to make any sales of Common Stock under the 2024 Sales Agreement. The offering of shares of Common Stock pursuant to the 2024 Sales Agreement will terminate upon the termination of the 2024 Sales Agreement as permitted therein.

The foregoing description of the 2024 Sales Agreement is qualified in its entirety by reference to the 2024 Sales Agreement, a copy of which will be filed as an exhibit to the 2024 Registration Statement (as defined below).

The shares of Common Stock being offered pursuant to the 2024 Sales Agreement will be offered and sold pursuant to a shelf registration statement on Form S-3 (the “2024 Registration Statement”) that we intend to file with the Securities and Exchange Commission and a prospectus relating to the ATM Program which will be included in the 2024 Registration Statement. None of our securities, including any shares of Common Stock, may be sold under the 2024 Sales Agreement, and no offers to buy such securities may be accepted, prior to the time the 2024 Registration Statement becomes effective.

The legal opinion of Latham & Watkins LLP relating to the shares of Common Stock being offered pursuant to the 2024 Sales Agreement will be filed as Exhibit 5.1 to the 2024 Registration Statement.

This report shall not constitute an offer to sell or the solicitation of an offer to buy the securities discussed herein, nor shall there be any offer, solicitation, or sale of the securities in any state in which such offer, solicitation or sale would be unlawful prior to registration or qualification under the securities laws of any such state.