uniQure NV

We operate an approximately 100,000 square foot GMP qualified manufacturing facility that we lease in Lexington, Massachusetts, U.S. The lease for the Lexington manufacturing facility, as amended to date, terminates in June 2029 and may be renewed for two subsequent five-year terms. In addition, we also operate approximately 12,000 square feet of multi-use office space in Lexington, Massachusetts, which is subject to a lease that expires in 2030 and may be renewed for one subsequent five-year term.

We operate approximately 111,000 square feet (seven floors) of multi-use space in Amsterdam, The Netherlands, which is subject to a lease that, as amended to date, terminates in 2032 with an option to extend the lease in five-year increments. To date we have entered into subleases with respect to two of the seven floors in the Amsterdam facility. We sublease an additional approximately 12,000 square feet of space in the Amsterdam facility, which is subject to a lease that expires in October 2028.

We believe that our facilities are adequate to meet current needs and that suitable alternative spaces will be available in the future on commercially reasonable terms.