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LIXTE BIOTECHNOLOGY HOLDINGS, INC.

For the period ended Dec 31, 2025. Filed Mar 31, 2026.

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A company's yearly report to the SEC, with audited financial statements. It is the fullest account a company gives of its business, its finances and the risks it sees.

FY2025 · Filed Mar 31, 2026

NMAD$3.57-0.8%Stored close · as of Nov 9, 2026

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Contents

SIGNATURES

In accordance with Section 13 and 15(d) of the Securities Exchange Act of 1934, the Registrant caused this report to be signed on its behalf by the undersigned thereunto duly authorized.

Date: March 31, 2026LIXTE BIOTECHNOLOGY HOLDINGS, INC.
(Registrant)
By:/s/ GEORDAN PURSGLOVE
Name:Geordan Pursglove
Title:President and Chief Executive Officer

In accordance with the Securities Exchange Act of 1934, this Report has been signed below by the following persons on behalf of the Registrant in the capacity and on the dates indicated.

SignatureTitleDate
/s/ GEORDAN PURSGLOVEPresident and Chief Executive OfficerMarch 31, 2026
Geordan Pursglove
/s/ PETER STAZZONEVice President and Chief Financial OfficerMarch 31, 2026
Peter Stazzone
/s/ JASON D. SAWYERDirectorMarch 31, 2026
Jason D. Sawyer
/s/ MICHAEL A. HOLLOWAYDirectorMarch 31, 2026
Michael A. Holloway
/s/ GUY W. PRIMUSDirectorMarch 31, 2026
Guy W. Primus
/s/ LOURDES FELIXDirectorMarch 31, 2026
Lourdes Felix

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The text of this filing, as the company filed it with the SEC, without its images or exhibits. This is not investment advice.