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GT Biopharma, Inc.

For the period ended Dec 31, 2025. Filed Mar 2, 2026.

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About this filing

A company's yearly report to the SEC, with audited financial statements. It is the fullest account a company gives of its business, its finances and the risks it sees.

FY2025 · Filed Mar 2, 2026

GTBP$3.96-8.3%Stored close · as of Nov 10, 2026

Extracted filing text, with the paragraph anchors used by the comparison.

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Item 15. Exhibits and Financial Statement Schedules

(a)(1) Financial Statements.

The financial statements of GT Biopharma, Inc. and the independent registered public accounting firm’s report dated March 2, 2026, are incorporated by reference to Item 8 of this report.

(a)(2) and (c) Financial Statement Schedules

Not required.

(a)(3) and (b) Exhibits

EXHIBIT INDEX

Incorporated by Reference
Exhibit Number · Exhibit Description · Form · Date · Number · Filed Herewith
3.1Restated Certificate of Incorporation as filed in Delaware September 10, 1996 and as thereafter amended through March 1, 200210-KSB04/01/20023.A
3.2Certificate of Amendment to the Restated Certificate of Incorporation of GT Biopharma, Inc., dated February 9, 201110-K03/31/20113.2
3.3Certificate of Amendment to the Restated Certificate of Incorporation of GT Biopharma, Inc., effective as of July 19, 20178-K/A03/15/20183.1
3.4Certificate of Amendment to the Restated Certificate of Incorporation of GT Biopharma, Inc., effective as of February 10, 20218-K02/11/20213.1
3.5Certificate of Amendment to the Restated Certificate of Incorporation of GT Biopharma, Inc., effective June 13, 202210-K03/30/20233.5
3.6Amended and Restated Bylaws of GT Biopharma, Inc., effective November 3, 20228-K11/09/20223.1
3.7Certificate of Amendment of Restated Certificate of Incorporation of GT Biopharma, Inc., effective February 1, 20248-K02/01/20243.1
4.1Certificate of Designation of Preferences, Rights and Limitations of Series J-1 Preferred Stock of GT Biopharma, Inc., dated April 3, 20198-K04/04/20193.1
4.2Certificate of Designation of Preferences, Rights and Limitations of Series K Preferred Stock of GT Biopharma, Inc., dated April 3, 201910-K04/16/20214.2
4.3Description of the Registrant’s Securities Registered pursuant to Section 12 of the Securities Exchange Act of 1934, as Amended10-K03/30/20234.3
4.4Form of Common Warrant8-K5/23/20244.1
4.5Form of Series A Inducement Warrant8-K02/26/20254.1
4.6Form of Series B Inducement Warrant8-K02/26/20254.2
4.7Form of Prefunded Common Stock Purchase Warrant.8-K04/04/20254.1
4.8Certificate of Designation of Preferences, Rights and Limitations of Series L 10% Convertible Preferred Stock.8-K05/13/20253.1
4.9Certificate of Increase to Certificate of Designation of Preferences, Rights and Limitations of Series L 10% Convertible Preferred Stock.8-K05/27/20253.1
4.10Form of Common Warrant.8-K05/13/20254.1
4.11Form of Vesting Warrant.8-K05/13/20254.2
10.1Exclusive License Agreement, dated July 18, 2016, between the Regents of the University of Minnesota and Oxis Biotech, Inc.10-Q08/11/201710.3
10.2Securities Purchase Agreement, dated January 30, 2020, among GT Biopharma, Inc. and the purchaser named therein10-Q05/15/202010.1
10.3Registration Rights Agreement, dated January 30, 2020, among GT Biopharma, Inc. and the purchaser named therein10-Q05/15/202010.2
10.4Form of Convertible Note (related to Securities Purchase Agreement, dated January 30, 2020)10-Q05/15/202010.3
10.5Form Securities Purchase Agreement among GT Biopharma, Inc. and the purchaser named therein (executed in April/May 2020)10-Q05/15/202010.4
10.6Form of Registration Rights Agreement among GT Biopharma, Inc. and the purchaser named therein (executed in April/May 2020)10-Q05/15/202010.5
10.7Form of Convertible Note (related to Securities Purchase Agreement executed in April/May 2020)10-Q05/15/202010.6
10.8Securities Purchase Agreement, dated July 7, 2020, among GT Biopharma, Inc. and the purchaser named therein8-K07/09/202010.1
10.9Registration Rights Agreement, dated July 7, 2020, among GT Biopharma, Inc. and the purchaser named therein8-K07/09/202010.3
10.10Form of Convertible Note (related to Securities Purchase Agreement, dated July 7, 2020)8-K07/09/20204.1
10.11Form of Standstill and Forbearance Agreement, dated June 23, 2020, between the Company and certain holders of convertible notes and debentures8-K06/23/202010.1
10.12Settlement Agreement, dated June 19, 2020, among GT Biopharma, Inc., Empery Asset Master Ltd., Empery Tax Efficient, LP and Empery Tax Efficient II, LP, Anthony Cataldo and Paul Kessler.8-K06/19/202010.1
10.13Form of Convertible Note, dated June 19, 2020 (related to Settlement Agreement, dated June 19, 2020)8-K06/19/202010.2
10.14Form of Pre-Funded Warrant to Purchase Common Stock, dated June 19, 2020 (related to Settlement Agreement, dated June 19, 2020)8-K06/19/202010.3
10.15Form of Convertible Note (related to Securities Purchase Agreement, dated September 16, 2020)8-K9/22/20204.1
10.16Securities Purchase Agreement, dated September 16, 2020, among GT Biopharma, Inc. and the purchasers named therein8-K9/22/202010.1
10.17Master Services Agreement, dated October 5, 2020, between GT Biopharma, Inc. and Cytovance Biologics, Inc.8-K10/6/202010.1
10.18Form of First Amendment and Extension of Standstill and Forbearance Agreement8-K11/4/202010.1
10.19Form of Secured Convertible Note8-K11/9/20204.1
10.20Securities Purchase Agreement8-K11/9/202010.1
10.21Settlement Agreement, dated as of November 9, 2020, by and among Adam Kasower, East Ventures, Inc., A British Virgin Islands company, SV Booth Investments III, LLC, a Delaware limited liability company and Theorem Group, LLC, a California LLC and GT Biopharma Inc., a Delaware corporation.10-Q11/13/202010.19
10.22Form of Settlement Note, dated November 9, 2020.10-Q11/13/202010.20
10.23Form of Amendment to Convertible Note & Standstill Agreement8-K12/23/202010.1
10.24Settlement Agreement, dated as of December 22, 2020, by and among Alto Opportunity Master Fund, SPC - Segregated Master Portfolio B, Anthony Cataldo, Paul Kessler and GT Biopharma Inc., a Delaware corporation.8-K12/28/202010.1
10.25Settlement Note, dated December 22, 2020, by GT Biopharma Inc. payable to Alto Opportunity Master Fund, SPC - Segregated Master Portfolio B.8-K12/28/202010.2
10.26Form of Second Amendment and Extension of Standstill and Forbearance Agreement.8-K02/1/202010.1
10.27Form of Amendment to Convertible Note, dated January 31, 20218-K02/1/202010.2
10.28Board Service Agreement with Michael Breen, dated January 12, 2021. ++S-1/A02/08/202110.70
10.29Amendment to Settlement Note with Alto Opportunity Master Fund, SPC - Segregated Master Portfolio B.S-1/A02/08/202110.71
10.30Form of Securities Purchase Agreement - December 2020 / January 2021 NotesS-1/A02/08/202110.72
10.31Form of December 2020 / January 2021 NoteS-1/A02/08/202110.73
10.32Exclusive License Agreement with Regents of the University of Minnesota, dated March 26, 2021.10-K03/28/202210.73
10.33Research Agreement with Regents of the University of Minnesota, dated June 16, 2021.10-K03/28/202210.74
10.34Employment Agreement with Michael Breen, entered into as of December 31, 2021 with an effective date of November 8, 2021. ++10-K03/28/202210.76
10.35Amendment No. 1 to Employment Agreement with Michael Breen, dated as of June 17, 2022. ++10-K3/26/202410.77
10.36Amendment No. 2 to Services Agreement with Michael Breen, dated as of February 20, 2023. ++10-K3/26/202410.78
10.37Board Service Agreement with Michael Breen dated November 11, 2020++10-Q05/16/202210.1
10.38Settlement and Investment Agreement dated August 24, 2022, by and between GT Biopharma, Inc. and Cytovance Biologics, Inc.**10-Q10/31/202210.1
10.39Form of Securities Purchase Agreement, dated December 2022, by and between GT Biopharma, Inc. and the purchasers named therein.8-K01/03/202310.1
10.40Form of Common Warrant8-K01/03/20234.1
10.41Form of Pre-Funded Warrant8-K01/03/20234.2
10.42Form of Placement Agent Warrant8-K01/03/20234.3
10.43Amendment No. 1 to Settlement and Investment Agreement, dated as of April 15, 2024, by and between GT Biopharma, Inc. and Cytovance Biologics, Inc.8-K04/30/202410.1
10.44Sponsored Research Agreement dated May 20, 2024 between GT Biopharma, Inc. and the Regents of the University of Minnesota.10-Q8/14/202410.3
10.45Form of Securities Purchase Agreement, dated May 21, 20248-K05/23/202410.1
10.46Form of Placement Agency Agreement, dated May 21, 20248-K05/23/202410.2
10.47Employment Agreement between the company and Alan Urban, dated as of June 7, 2024.8-K06/07/202410.1
10.48Investigator Initiated Clinical Trial Agreement, dated as of November 18, 2024, by and between GT Biopharma, Inc. and the Regents of the University of Minnesota.8-K11/21/202410.1
10.49Form of Inducement Letter.8-K02/26/202510.1
10.50Securities Purchase Agreement, dated as of May 12, 2025, between the Company and the purchasers identified therein.8-K05/13/202510.1
10.51Registration Rights Agreement, dated as of May 12, 2025, between the Company and the purchasers identified therein.8-K05/13/202510.2
10.52Form of Voting Agreement.8-K05/13/202510.3
10.53Form of Lock-up Agreement.8-K05/13/202510.4
10.54First Amendment to Securities Purchase Agreement, dated as of May 21, 2025, between the Company and the purchasers identified therein.8-K05/27/202510.1
10.55Joinder to Registration Rights Agreement, dated as of May 21, 2025, between the Company and the purchaser identified therein.8-K05/27/202510.2
10.56First Amendment to Common Shares Purchase Agreement, dated as of June 10, 2025, between the Company and the investors identified therein.8-K06/11/202510.1
10.57First Amendment to the Research Agreement, effective as of June 18, 2025, between the Company and the Regents of the University of Minnesota10-Q08/14/202510.8
10.58Amendment No. 3 to the Employment Agreement, dated August 26, 2025, by and between GT Biopharma, Inc. and Michael Breen8-K08/29/202510.1
10.59Form of Waiver (incorporated by reference to exhibit 10.1 of GT Biopharma, Inc.’s Form 8-K filed with the Securities and Exchange Commission on September 23, 2025)8-K09/26/202510.1
14.1Code of Ethics10-K03/31/201514.1
19.1Insider Trading PolicyX
23.1Consent of Weinberg & Company, P.A.X
24.1Power of Attorney (included on signature page)
31.1Certification of the Principal Executive Officer pursuant to Rule 13a-14(a)/15d-14(a), as adopted pursuant to Section 302 of the Sarbanes-Oxley Act of 2002.X
31.2Certification of the Principal Financial Officer pursuant to Rule 13a-14(a)/15d-14(a), as adopted pursuant to Section 302 of the Sarbanes-Oxley Act of 2002.X
32.1Certification of the Principal Executive Officer pursuant to 18 U.S.C. Section 1350, as adopted pursuant to Section 906 of the Sarbanes-Oxley Act of 2002. *X
32.2Certification of the Principal Financial Officer pursuant to 18 U.S.C. Section 1350, as adopted pursuant to Section 906 of the Sarbanes-Oxley Act of 2002. *X
97.1Compensation Recovery Policy of GT Biopharma, Inc., dated November 3, 202310-K/A04/14/202597.1
101.INSInline XBRL Instance Document.X
101.SCHInline XBRL Taxonomy Extension Schema Document.X
101.CALInline XBRL Taxonomy Extension Calculation Linkbase Document.X
101.DEFInline XBRL Taxonomy Extension Definition Linkbase Document.X
101.LABInline XBRL Taxonomy Extension Label Linkbase Document.X
101.PREInline XBRL Taxonomy Extension Presentation Linkbase Document.X
104Cover Page Interactive Data File – The cover page interactive data file does not appear in the Interactive Data File because its XBRL tags are embedded within the Inline XBRL document.

++ Indicates management contract or compensatory plan.

  • This certification shall not be deemed “filed” for purposes of Section 18 of the Exchange Act, or otherwise subject to the liability of that Section, nor shall it be deemed to be incorporated by reference into any filing under the Securities Act or the Exchange Act.

**The Registrant has omitted portions of this exhibit that are both not material and the type of information that the Registrant treats as private or confidential.

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