OMEROS CORP

For the period ended Dec 31, 2025. Filed Mar 31, 2026.

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A company's yearly report to the SEC, with audited financial statements. It is the fullest account a company gives of its business, its finances and the risks it sees.

FY2025 · Filed Mar 31, 2026

OMER$17.55+3.7%Stored close · as of Nov 9, 2026

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Contents

OMEROS CORPORATION

ANNUAL REPORT ON FORM 10-K FOR THE YEAR ENDED December 31, 2025

INDEX

Page
Part I	1
	Item 1. Business	1
	Item 1A. Risk Factors	22
	Item 1B. Unresolved Staff Comments	34
	Item 1C. Cybersecurity	34
	Item 2. Properties	34
	Item 3. Legal Proceedings	34
	Item 4. Mine Safety Disclosures	34
Part II	35
	Item 5. Market for Registrant’s Common Equity, Related Shareholder Matters and Issuer Purchases of Equity Securities	35
	Item 6. [Reserved]	36
	Item 7. Management’s Discussion and Analysis of Financial Condition and Results of Operations	36
	Item 7A. Quantitative and Qualitative Disclosures About Market Risk	47
	Item 8. Financial Statements and Supplementary Data	48
	Item 9. Changes in and Disagreements with Accountants on Accounting and Financial Disclosures	69
	Item 9A. Controls and Procedures	69
	Item 9B. Other Information	70
	Item 9C. Disclosures Regarding Foreign Jurisdictions that Prevent Inspection	70
Part III	70
	Item 10. Directors, Executive Officers and Corporate Governance	70
	Item 11. Executive Compensation	70
	Item 12. Security Ownership of Certain Beneficial Owners and Management and Related Shareholder Matters	71
	Item 13. Certain Relationships and Related Transactions, and Director Independence	71
	Item 14. Principal Accounting Fees and Services	72
Part IV	72
	Item 15. Exhibits, Financial Statement Schedules	72
Signatures	79

iii

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