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OMEROS CORP

For the period ended Dec 31, 2025. Filed Mar 31, 2026.

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About this filing

A company's yearly report to the SEC, with audited financial statements. It is the fullest account a company gives of its business, its finances and the risks it sees.

FY2025 · Filed Mar 31, 2026

OMER$17.30-1.4%Stored close · as of Nov 10, 2026

Extracted filing text, with the paragraph anchors used by the comparison.

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Contents

Item 15. Exhibits, Financial Statement Schedules

1. Financial Statements

See the Index to Consolidated Financial Statements in Part II, Item 8 of this Form 10-K.

2. Financial Statement Schedules

All schedules have been omitted as the required information is either not required, not applicable or otherwise included in the Financial Statements and notes thereto.

3. Exhibits

The following list of exhibits includes exhibits submitted with this Form 10-K as filed with the SEC and those incorporated by reference to other filings.

EXHIBIT INDEX

Incorporated by Reference
Exhibit No. · Exhibit Description · Form · File No. · Exhibit No. · Filing Date · Filed Herewith
1.1Sales Agreement, dated March 1, 2021, between Omeros Corporation and Cantor Fitzgerald & Co.10-K001-344751.103/01/2021
3.1Amended and Restated Articles of Incorporation of Omeros Corporation10-K001-344753.103/31/2010
3.2Amended and Restated Bylaws of Omeros Corporation10-K001-344753.203/31/2010
4.1Description of Common Stock10-K001-344754.103/01/2021
4.2Form of Omeros Corporation Common Stock CertificateS-1/A333-1485724.110/02/2009
4.3Indenture, dated as of August 14, 2020, between Omeros Corporation and Wells Fargo Bank, National Association, as trustee8-K001-344754.108/14/2020
4.4Second Supplemental Indenture, dated as of May 14, 2025, between the Company and Computershare Trust Company, National Association, as trustee (including the form of 9.50% Convertible Senior Notes due 2029)8-K/A001-344754.205/16/2025
10.1*Form of Indemnification Agreement entered into between Omeros Corporation and its directors and officersS-1333-14857210.101/09/2008
10.2*2008 Equity Incentive Plan (as amended)10-K001-3447510.603/16/2017
10.3*Form of Stock Option Award Agreement under the 2008 Equity Incentive Plan10-Q001-3447510.211/07/2013
10.4*2017 Omnibus Incentive Compensation Plan (as amended and restated effective as of June 23, 2023)8-K001-3447510.106/28/2023
10.5*Form of Stock Option Award Agreement under the 2017 Omnibus Incentive Compensation PlanS-8333-2188824.406/21/2017
10.6*Second Amended and Restated Employment Agreement between Omeros Corporation and Gregory A. Demopulos, M.D. dated April 7, 20108-K001-3447510.104/12/2010
10.7*Omeros Corporation Non-Employee Director Compensation Policy10-K001-3447510.1103/13/2023
10.8Lease dated January 27, 2012 between Omeros Corporation and BMR-201 Elliott Avenue LLC8-K001-3447510.102/01/2012
10.9First Amendment to Lease dated November 5, 2012 between Omeros Corporation and BMR-201 Elliott Avenue LLC10-Q001-3447510.211/09/2012
10.10Second Amendment to Lease dated November 16, 2012 between Omeros Corporation and BMR-201 Elliott Avenue LLC10-K001-3447510.1803/18/2013
10.11Third Amendment to Lease dated October 16, 2013 between Omeros Corporation and BMR-201 Elliott Avenue LLC10-K001-3447510.1803/13/2014
10.12Fourth Amendment to Lease dated September 8, 2015 between Omeros Corporation and BMR-201 Elliott Avenue LLC10-Q001-3447510.311/09/2015
10.13Fifth Amendment to Lease dated September 1, 2016 between Omeros Corporation and BMR-201 Elliott Avenue LLC10-Q001-3447510.105/10/2017
10.14Sixth Amendment to Lease dated October 18, 2018 between Omeros Corporation and BMR-201 Elliott Avenue LLC10-K001-3447510.1903/01/2019
10.15Seventh Amendment to Lease dated April 15, 2019 between Omeros Corporation and BMR-201 Elliott Avenue LLC10-Q001-3447510.108/08/2019
10.16Eighth Amendment to Lease dated October 18, 2019 between Omeros Corporation and BMR-201 Elliott Avenue LLC10-K001-3447510.2003/02/2020
10.17Ninth Amendment to Lease dated January 15, 2020 between Omeros Corporation and BMR-201 Elliott Avenue LLC10-Q001-3447510.105/11/2020
10.18Tenth Amendment to Lease dated September 15, 2020 between Omeros Corporation and BMR-201 Elliott Avenue LLC10-Q001-3447510.111/09/2020
10.19Eleventh Amendment to Lease dated October 23, 2020 between Omeros Corporation and BMR-201 Elliott Avenue LLC10-K001-3447510.2303/01/2021
10.20Twelfth Amendment to Lease dated January 1, 2021 between Omeros Corporation and BMR-201 Elliott Avenue LLC10-K001-3447510.2403/01/2021
10.21Thirteenth Amendment to Lease dated January 1, 2021 between Omeros Corporation and BMR-201 Elliott Avenue LLC10-Q001-3447510.108/09/2021
10.22Fourteenth Amendment to Lease dated January 14, 2022 between Omeros Corporation and BMR-201 Elliott Avenue LLC10-Q001-3447510.105/10/2022
10.23Fifteenth Amendment to Lease dated November 1, 2022 between Omeros Corporation and BMR-201 Elliott Avenue LLC10-Q001-3447510.308/07/2024
10.24Sixteenth Amendment to Lease dated July 8, 2024 between Omeros Corporation and BMR-201 Elliott Avenue LLC10-Q001-3447510.111/13/2024
10.25Seventeenth Amendment to Lease dated December 18, 2024 between Omeros Corporation and BMR-201 Elliott Avenue LLC10-K001-3447510.2503/31/2025
10.26†License Agreement between Omeros Corporation and Daiichi Sankyo Co., Ltd. (successor-in-interest to Asubio Pharma Co., Ltd.) dated March 3, 201010-K001-3447510.2304/01/2024
10.27†Amendment No. 1 to License Agreement with an effective date of January 5, 2011 between Omeros Corporation and Daiichi Sankyo Co., Ltd.10-K001-3447510.2404/01/2024
10.28†Amendment No. 2 to License Agreement with an effective date of January 25, 2013 between Omeros Corporation and Daiichi Sankyo Co., Ltd.10-K001-3447510.2504/01/2024
10.29†Combined Development and Commercial Supply Agreement, effective as of May 16, 2018, between Omeros Corporation and Vetter Pharma international GmbH10-K001-3447510.3003/31/2025
10.30†Master Services Agreement, dated July 28, 2019, between Omeros Corporation and Lonza Biologics Tuas Pte. Ltd.10-Q001-3447510.111/12/2019
10.31†Asset Purchase Agreement, dated as of December 1, 2021 among Omeros Corporation, Rayner Surgical Inc. and Rayner Surgical Group, Limited, as Parent Guarantor10-K001-3447510.103/01/2022
10.32†Amended and Restated Royalty Purchase Agreement between Omeros Corporation and DRI Healthcare Acquisitions LP dated February 1, 202410-K001-3447510.3004/01/2024
10.33†Asset Purchase and License Agreement, dated as of October 10, 2025, between Omeros Corporation and Novo Nordisk Health Care AGX
19.1Omeros Corporation Insider Trading Policy10-K001-3447519.103/31/2025
23.1Consent of Independent Registered Public Accounting FirmX
31.1Certification of Principal Executive Officer Pursuant to Rule 13-14(a) or Rule 15d-14(a) of the Securities Exchange Act of 1934 as Adopted Pursuant to Section 302 of the Sarbanes-Oxley Act of 2002X
31.2Certification of Principal Financial Officer Pursuant to Rule 13-14(a) or Rule 15d-14(a) of the Securities Exchange Act of 1934 as Adopted Pursuant to Section 302 of the Sarbanes-Oxley Act of 2002X
32.1Certification of Principal Executive Officer Pursuant to 18 U.S.C. Section 1350, as Adopted Pursuant to Section 906 of the Sarbanes-Oxley Act of 2002X
32.2Certification of Principal Financial Officer Pursuant to 18 U.S.C. Section 1350, as Adopted Pursuant to Section 906 of the Sarbanes-Oxley Act of 2002X
97.1Omeros Corporation Compensation Clawback Policy10-K001-3447597.104/01/2024
101.INSInline XBRL Instance DocumentX
101.SCHInline XBRL Taxonomy Extension Schema DocumentX
101.CALInline XBRL Taxonomy Extension Calculation Linkbase DocumentX
101.DEFInline XBRL Taxonomy Extension Definition Linkbase DocumentX
101.LABInline XBRL Taxonomy Extension Labels Linkbase DocumentX
101.PREInline XBRL Taxonomy Extension Presentation Linkbase DocumentX
104.1Cover Page Interactive Data File, formatted in Inline XBRL (included in Exhibit 101)X
*Indicates management contract or compensatory plan or arrangement.
†Certain identified information has been excluded from the exhibit because it both (A) is not material and (B) is the type that the registrant treats as private or confidential.
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The text of this filing, as the company filed it with the SEC, without its images or exhibits. This is not investment advice.