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Monopar Therapeutics

For the period ended Dec 31, 2025. Filed Mar 27, 2026.

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About this filing

A company's yearly report to the SEC, with audited financial statements. It is the fullest account a company gives of its business, its finances and the risks it sees.

FY2025 · Filed Mar 27, 2026

MNPR$73.75+3.3%Stored close · as of Nov 9, 2026

Extracted filing text, with the paragraph anchors used by the comparison.

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Contents

Item 15. Exhibits, Financial Statement Schedule

1. Financial Statements

INDEX TO FINANCIAL STATEMENTS

Page
Report of Independent Registered Public Accounting Firm (PCAOB ID: 207)F-2
Consolidated Balance Sheets as of December 31, 2025 and 2024F-3
Consolidated Statements of Operations and Comprehensive Loss for the Years Ended December 31, 2025 and 2024F-4
Consolidated Statements of Stockholders’ Equity for the Years Ended December 31, 2025 and 2024F-5
Consolidated Statements of Cash Flows for the Years Ended December 31, 2025 and 2024F-6
Notes to Consolidated Financial StatementsF-7 to F-23

2. Financial Statements Schedules

Other financial statements schedules are not included because they are not required, or the information is otherwise shown in the Consolidated Financial Statements or notes thereto.

(b) Exhibits

The following exhibits are filed as part of this Annual Report on Form 10-K.

ExhibitDocumentIncorporated by Reference From:
3.2Certificate of Amendment to the Second Amended and Restated Certificate of IncorporationForm 8-K filed on August 9, 2024
3.3Amended and Restated BylawsForm 10-Q filed on May 12, 2022
4.1Description of Registered SecuritiesFiled herewith as Exhibit 4.1
4.2Form of Pre-funded WarrantForm 8-K filed on December 23,2024
10.5Employment Agreement of Chandler D. Robinson – effective November 1, 2017Form 10-K filed on March 26, 2018
10.6Consulting Agreement of pRx Consulting (Patrice Rioux) – effective January 1, 2026Filed herewith as Exhibit 10.6
10.7Consulting Agreement of Christopher M. Starr – effective January 1, 2022Form 10-K filed on March 24, 2022
10.8*License Agreement with Alexion Pharmaceuticals, Inc.Form 8-K filed on October 24, 2024
10.9Common Stock Investment Agreement with Alexion Pharmaceuticals, Inc.Form 8-K filed on October 24, 2024
10.10Securities Purchase AgreementForm 8-K filed on October 30, 2024
10.11Securities Purchase AgreementForm 8-K filed on December 23, 2024
10.12Registration Rights AgreementForm 8-K filed on December 23, 2024
10.15Share Purchase Agreement with Tactic Pharma, LLCForm 8-K filed on September 24, 2025
10.16Employment Agreement with Susan Rodriguez – effective March 2, 2026Filed herewith as Exhibit 10.16
19.1Insider Trading PolicyFiled herewith as Exhibit 19.1
21.1Subsidiaries of Monopar Therapeutics Inc. as of December 31, 2025Filed herewith as Exhibit 21.1
23.1Consent of BPM LLP, Independent Registered Public Accounting FirmFiled herewith as Exhibit 23.1
24.1Power of Attorney (included in the signature page hereto)
31.1Certification of Chandler D. Robinson, Chief Executive OfficerFiled herewith as Exhibit 31.1
31.2Certification of Quan Vu, Chief Financial OfficerFiled herewith as Exhibit 31.2
32.1Certification of Chandler D. Robinson, Chief Executive Officer and Quan Vu, Chief Financial OfficerFiled herewith as Exhibit 32.1
101.INSInline XBRL Taxonomy Extension Schema
101.SCHInline XBRL Taxonomy Extension Schema
101.CALInline XBRL Taxonomy Extension Calculation Linkbase
101.DEFInline XBRL Taxonomy Extension Definition Linkbase
101.LABInline XBRL Taxonomy Extension Label Linkbase
101.PREInline XBRL Taxonomy Extension Presentation Linkbase
104Cover Page Interactive Data File (formatted as inline XBRL and contained in Exhibit 101)

Confidential Information has been omitted and filed separately with the SEC on exhibits marked with (*).

SIGNATURES

Pursuant to the requirements of Section 13 or 15(d) of the Securities Exchange Act of 1934, the registrant has duly caused this report to be signed on its behalf by the undersigned, thereunto duly authorized.

MONOPAR THERAPEUTICS INC
Dated: March 27, 2026By:/s/ Quan Vu
Name: Quan Vu
Title: Chief Financial Officer
(Principal Financial Officer)
ContentsView on SEC.gov

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