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Phio Pharmaceuticals Corp.

For the period ended Dec 31, 2025. Filed Mar 5, 2026.

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About this filing

A company's yearly report to the SEC, with audited financial statements. It is the fullest account a company gives of its business, its finances and the risks it sees.

FY2025 · Filed Mar 5, 2026

PHIO$0.81-3.1%Stored close · as of Nov 10, 2026

Extracted filing text, with the paragraph anchors used by the comparison.

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Contents

Item 15. EXHIBIT AND FINANCIAL STATEMENT SCHEDULES

ITEM 15.EXHIBITS AND FINANCIAL STATEMENT SCHEDULES

Financial Statements

Our consolidated financial statements are set forth in Item 8 to this Annual Report on Form 10-K.

Financial Statement Schedules

Certain schedules are omitted because they are not applicable, or are not required by smaller reporting companies.

Exhibits

ExhibitIncorporated by Reference Herein
NumberDescriptionFormDate
3.1Amended and Restated Certificate of Incorporation of Phio Pharmaceuticals Corp.Current Report on Form 8-K (File No. 001-36304)November 19, 2018
3.2Certificate of Amendment to the Amended and Restated Certificate of Incorporation of Phio Pharmaceuticals Corp.Current Report on Form 8-K (File No. 001-36304)January 14, 2020
3.3Certificate of Amendment to the Amended and Restated Certificate of Incorporation of Phio Pharmaceuticals Corp.Current Report on Form 8-K (File No. 001-36304)January 25, 2023
3.4Certificate of Amendment to the Amended and Restated Certificate of Incorporation of Phio Pharmaceuticals Corp.Current Report on Form 8-K (File No. 001-36304)July 2, 2024
3.5Certificate of Designation of Series D Preferred Stock, dated November 16, 2022.Current Report on Form 8-K (File No. 001-36304)November 16, 2022
3.6Amended and Restated Bylaws of Phio Pharmaceutical Corp.Current Report on Form 8-K (File No. 001-36304)May 2, 2022
4.1Form of Warrant.Amendment No. 1 to the Registration Statement on Form S-1 (File No. 333-221173)September 28, 2018
ExhibitIncorporated by Reference Herein
NumberDescriptionFormDate
4.2Form of Warrant.Current Report on Form 8-K (File No. 001-36304)April 2, 2020
4.3Form of Common Stock Warrant.Current Report on Form 8-K (File No. 001-36304)January 25, 2021
4.4Form of Placement Agent Warrant.Current Report on Form 8-K (File No. 001-36304)February 17, 2021
4.5Form of Placement Agent Warrant.Current Report on Form 8-K (File No. 001-36304)December 8, 2023
4.6Description of Securities Registered Pursuant to Section 12(b) of the Securities Exchange Act of 1934.Annual Report on Form 10-K (File No. 00136304)April 1, 2024
4.7Form of Series C/D WarrantCurrent Report on Form 8-K (File No. 001-36304)July 12, 2024
4.8Form of Placement Agent WarrantCurrent Report on Form 8-K (File No. 001-36304)July 12, 2024
4.9Form of Placement Agent WarrantCurrent Report on Form 8-K (File No. 001-36304)December 20, 2024
ExhibitIncorporated by Reference Herein
NumberDescriptionFormDate
4.10Form of Placement Agent WarrantCurrent Report on Form 8-K (File No. 001-36304)December 26, 2024
4.11Form of Placement Agent WarrantCurrent Report on Form 8-K (File No. 001-36304)January 15, 2024
4.12Form of Placement Agent WarrantCurrent Report on Form 8-K (File No. 001-36304)January 17, 2024
4.13Form of Series J/K WarrantCurrent Report on Form 8-K (File No. 001-36304)July 30, 2025
4.14Form of Placement Agent WarrantCurrent Report on Form 8-K (File No. 001-36304)July 30, 2025
4.15Form of Series A WarrantCurrent Report on Form 8-K (File No. 001-36304)November 6, 2025
4.16Form of Placement Agent WarrantCurrent Report on Form 8-K (File No. 001-36304)November 13, 2025
10.1Patent and Technology Assignment Agreement between RXi Pharmaceuticals Corporation (formerly RNCS, Inc.) and Advirna, LLC, effective as of September 24, 2011.Registration Statement on Form S-1 (File No. 333-177498)October 25, 2011
10.2Phio Pharmaceuticals Corp. 2020 Long Term Incentive Plan, as amended and restated.#Current Report on Form 10-Q (File No. 001-36304)June 21, 2024
10.3Form of Restricted Stock Unit Award under the Company’s 2020 Long Term Incentive Plan.#Annual Report on Form 10-K (File. 001-36304)March 25, 2021
10.4Form of Nonqualified Stock Option Award under the Company’s 2020 Long Term Incentive Plan.#Annual Report on Form 10-Q (File. 001-36304)November 9, 2023
10.5Phio Pharmaceuticals Corp. 2012 Long Term Incentive Plan.#Quarterly Report on Form 10-Q (File No. 001-36304)November 12, 2019
10.6Form of Restricted Stock Unit Award under the Company’s 2012 Long Term Incentive Plan, as amended.#Amendment No. 2 to the Registration Statement on Form S-1 (File No. 333-177498)December 29, 2011
ExhibitIncorporated by Reference Herein
NumberDescriptionFormDate
10.7Form of Incentive Stock Option Award under the Company’s 2012 Long Term Incentive Plan, as amended.#Registration Statement on Form S-1 (File No. 333-191236)September 18, 2013
10.8Form of Non-Qualified Stock Option Award under the Company’s 2012 Long Term Incentive Plan, as amended.#Registration Statement on Form S-1 (File No. 333-191236)September 18, 2013
10.9RXi Pharmaceuticals Corporation Employee Stock Purchase Plan.#Registration Statement on Form S-8 (File No. 333-277013)August 24, 2018
10.10Form of Indemnification Agreement.#Amendment No. 3 to the Registration Statement on Form S-1 (File No. 333-177498)January 23, 2012
10.11Employment Agreement, dated February 20, 2023, by and between Phio Pharmaceuticals Corp. and Robert Bitterman.#Current Report on Form 8-K (File No. 001-36304)February 22, 2023
10.12First Amendment to the Employment Agreement of Robert J. Bitterman, dated March 25, 2025, by and between the Company and Robert Bitterman.#Quarterly Report on Form 10-Q (File No. 001-36304)March 31, 2025
10.13Second Amendment to the Employment Agreement of Robert J. Bitterman, dated February 17, 2026, by and between the Company.#Current Report on Form 8-K (File No. 001-36304)February 18, 2026
10.14Lease Agreement dated December 17, 2013 between RXi Pharmaceuticals Corporation and 257 Simarano Drive, LLC, Brighton Properties, LLC, Robert Stubblebine 1, LLC and Robert Stubblebine 2, LLC.Current Report on Form 8-K (File No. 000-54910)December 20, 2013
10.15First Amendment to Lease dated January 22, 2019.Current Report on Form 8-K (File No. 001-36304)January 28, 2019
10.16Registration Rights Agreement, dated January 21, 2021, by and between the Company and the Purchasers signatory therein.Current Report on Form 8-K (File No. 001-36304)January 25, 2021
ExhibitIncorporated by Reference Herein
NumberDescriptionFormDate
10.17Form of Inducement Letter Agreement, dated July 11, 2024, by and between the Company and the Holders.Current Report on Form 8-K (File No. 001-36304)July 12, 2024
10.18Offer Letter, executed April 21, 2025 by and between the Company and Lisa Carson.Current Report on Form 8-K (File No. 001-36304)June 12, 2025
10.19Form of Inducement Letter Agreement dated November 3, 2025, by and between Phio Pharmaceuticals Corp. and the Holders.Current Report on Form 8-K (File No. 001-36304)November 13, 2025
23.1Consent of BDO USA, P.C., an Independent Registered Public Accounting Firm.*
23.2Consent of Grant Thornton LLP, an independent Registered Public Accounting Firm.*
31.1Sarbanes-Oxley Act Section 302 Certification of Principal Executive Officer.*
31.2Sarbanes-Oxley Act Section 302 Certification of Principal Financial Officer.*
ExhibitIncorporated by Reference Herein
NumberDescriptionFormDate
32.1Sarbanes-Oxley Action Section 906 Certification of Principal Executive Officer and Principal Financial Officer.**
97.1Phio Pharmaceuticals Corp. Incentive Compensation Recovery Policy.#Annual Report on Form 10-K (File No. 001-35304)April 1, 2024
101.INSInline XBRL Instance Document.*
101.SCHInline XBRL Taxonomy Extension Schema Document.*
101.CALInline XBRL Taxonomy Extension Calculation Linkbase Document.*
101.DEFInline XBRL Taxonomy Extension Definition Linkbase Document.*
101.LABInline XBRL Taxonomy Extension Label Linkbase Document.*
101.PREInline XBRL Taxonomy Extension Presentation Linkbase Document.*
104The cover page for this report, formatted in Inline XBRL (included in Exhibit 101).*
*Filed herewith.
**Furnished herewith.
#Indicates a management contract or compensatory plan or arrangement.
+Certain portions of this Exhibit have been redacted pursuant to Item 601(b)(10) of Regulation S-K. The Company agrees to furnish supplementally an unredacted copy of this Exhibit to the SEC upon request.
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