Compensation of Directors and Executive Officers
Executive Compensation
This section provides information, in tabular and narrative formats specified in applicable SEC rules, regarding the amounts of compensation paid to each of our named executive officers, or NEOs, and related information. As a smaller reporting company, the Company has presented such information in accordance with the scaled disclosure requirements permitted under applicable SEC regulations.
The following table sets forth certain information concerning all cash and non-cash compensation awarded to, earned by or paid to our each of NEOs for the years ended December 31, 2024 and 2023:
2024 Summary Compensation Table
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| · · · · · · · · · · Non-Equity · · · · |
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| · · · · · · Stock · · Option · · Incentive Plan · · All Other · · |
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| · · · · Salary · · Awards · · Awards · · Compensation · · Compensation · · |
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| Name and Principal Position | Year | ($) | ($)(1) | ($) (1) | ($) (2) | ($) (3) | Total ($) |
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| James V. Caruso | 2024 | 650,000 | –‒ | 2,214,000 | 178,750 | –‒ | 3,042,750 |
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| President and Chief Executive Officer | 2023 | 600,000 | 107,582 | 715,140 | 450,000 | 92,418 | 1,965,140 |
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| Jarrod Longcor | 2024 | 500,000 | –‒ | 1,230,000 | 100,000 | –‒ | 1,830,000 |
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| Chief Operating Officer | 2023 | 480,000 | 113,758 | 394,560 | 288,000 | 86,242 | 1,362,560 |
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| Chad J. Kolean | 2024 | 425,000 | –‒ | 713,400 | 85,000 | –‒ | 1,223,400 |
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| Chief Financial Officer | 2023 | 390,000 | 112,770 | 284,960 | 234,000 | 87,230 | 1,108,960 |
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| (1) | The reported amounts represent the aggregate grant date fair value computed in accordance with Financial Accounting Standards Board Accounting Standards Codification Topic 718, Compensation-Stock Compensation (“ASC 718”). In the case of stock awards, the grant date fair value was determined based on the stock price on the grant date. All assumptions made regarding the valuation of option awards can be referenced in Note 7 in the Notes to Restated Consolidated Financial Statements included in this prospectus. The amounts reported for 2024 include stock option awards to Messrs. Caruso, Longcor and Kolean with respect to 900,000 shares, 500,000 shares, and 290,000 shares, respectively, which awards were approved by the Compensation |
Committee on November 30, 2023, subject to stockholder approval of an amendment to the Company’s 2021 Stock Incentive Plan (the “2021 Plan”) at the 2024 annual meeting of stockholders. Because stockholder approval was received in 2024, these stock option awards are considered granted in 2024 under ASC 718 and are reflected as 2024 compensation in the 2024 Summary Compensation Table.
| (2) | Amounts in this column represent bonuses approved by the Compensation Committee based on its annual review of the performance of the executive officers against predetermined financial and strategic objectives established for the year. NEOs are paid the same percentage upon the achievement of financial objectives and may be paid varied percentages upon the achievement of strategic objectives depending on the subject matter. |
| (3) | The methodology used to compute the aggregate incremental cost of perquisites and other personal benefits for each individual NEO is based on the total cost to the Company, and such costs are required to be reported under SEC rules when the total costs are equal to or greater than $10,000 in the aggregate for a NEO. The amounts presented are exclusively cash bonuses paid to the NEOs to satisfy the tax withholding obligations associated with fully vested stock awards received by the NEOs on December 8, 2023 following the release of positive top-line data. |
Equity Awards
As described in Note (1) to the 2024 Summary Compensation Table above, on November 30, 2023 the Compensation Committee approved stock option awards to Messrs. Caruso, Longcor and Kolean with respect to 900,000 shares, 500,000 shares, and 290,000 shares, respectively, subject to stockholder approval of an amendment to the 2021 Plan at the 2024 annual meeting of stockholders. These options are scheduled to vest one-third on the first anniversary of the grant date and in 24 equal monthly installments thereafter, subject to continuous employment with the Company through each vesting date.
Employment Agreements
*James V. Caruso.*We entered into an employment agreement with Mr. Caruso as of June 15, 2015, as amended and restated on April 15, 2019, pursuant to which Mr. Caruso serves as President and Chief Executive Officer of the Company. Under the agreement, the Company pays Mr. Caruso a base salary that is adjusted from time to time. Mr. Caruso is also eligible for an annual bonus, based on performance, with an initial target of up to 50% of his base salary at the discretion of the Compensation Committee. If Mr. Caruso is terminated other than for cause or by Mr. Caruso for good reason within 12 months after a change in control (i.e. double trigger), he is entitled to severance in an amount equal to (i) 24 months of base salary, (ii) his then applicable target bonus payable over 24 months (a total of 1.5x the annual target bonus payable at the time of termination) and (iii) 24 months of payment or reimbursement of health insurance (equal to the premium paid by the Company prior to the date of termination), each payable in installments over 24 months. Following a termination of employment by the Company without cause or by Mr. Caruso for good reason that is not within 12 months after a change in control, Mr. Caruso is entitled to severance in an amount equal to 12 months base salary plus payment or reimbursement of health insurance for 12 months (equal to the premium paid by the Company prior to the date of termination). Each of the foregoing severance benefits is conditioned on Mr. Caruso’s execution of a release agreement in favor of the Company.
Jarrod Longcor. We entered into an employment agreement with Mr. Longcor as of July 15, 2016, as amended and restated on April 15, 2019, and amended on November 10, 2019. Under the agreement, Mr. Longcor receives a base salary that may be adjusted from time to time. Mr. Longcor is eligible for an annual bonus, based on performance, with an initial target of up to 30% of his base salary. If Mr. Longcor’s employment is terminated other than for cause or by Mr. Longcor for good reason, contingent upon the execution of a release agreement in favor of the Company, Mr. Longcor is entitled to (i) severance in an amount equal to nine months of Mr. Longcor’s annual base salary, provided that if such termination occurs within 12 months after a change in control (i.e. double trigger), such severance is increased to 18 months of Mr. Longcor’s full base salary, each payable in monthly installments, (ii) payment or reimbursement of health insurance (for nine or 18 months, as applicable), each payable in monthly installments, (iii) a payment amount equal to the annual bonus Mr. Longcor would have received for the calendar year in which the termination occurred prorated for the number of days elapsed in such year, and (iv) outplacement services not to exceed $7,500.
Chad J. Kolean. We entered into an employment agreement with Mr. Kolean as of February 22, 2022. Pursuant to his employment agreement, Mr. Kolean receives a base salary that may be adjusted from time to time and is eligible to receive an annual performance bonus with a target amount equal to 40% of his base salary. In the event of a dismissal without cause or resignation by Mr. Kolean for good reason, Mr. Kolean will be entitled to nine months of severance. In the event of dismissal without cause or
resignation by Mr. Kolean for good reason, within the eighteen months following a change in control, Mr. Kolean will be entitled to eighteen months of severance.
2024 Outstanding Equity Awards at Fiscal Year-End
The following table sets forth certain information with respect to outstanding equity awards as of December 31, 2024, with respect to our NEOs.
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| | | | | Option Awards | | | | Stock Awards |
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| · · · · · · · · · · · · · · · Market |
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| · · · · · · · · · · · · · Number of · · Value |
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| · · · · Number of · · Number of · · · · · · · Shares or · · of Shares or |
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| · · · · securities · · securities · · · · · · · Units of · · Units of |
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| · · · · underlying · · underlying · · Option · · · · Stock · · Stock |
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| · · · · unexercised · · unexercised · · Exercise · · Option · · that Have · · that Have |
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| · · · · options (#) · · options (#) · · Price · · Expiration · · Not · · Not |
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| Name · Date of Award · exercisable · unexercisable · ($/share) · date · Vested (#) · Vested ($) |
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| James V. Caruso | 11/30/2023(1) | 300,060 | 599,940 | | $2.65 | 11/30/2033 | — | — |
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| | 1/17/2023(1) | 333,518 | 188,482 | | $1.68 | 1/17/2033 | — | — |
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| | 1/25/2022(1) | 137,958 | 3,942 | | $5.50 | 1/25/2032 | — | — |
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| | 3/4/2021 | 160,000 | — | | $17.40 | 3/4/2031 | — | — |
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| | 2/3/2020 | 10,000 | — | | $27.10 | 2/3/2030 | — | — |
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| | 1/17/2019 | 7,500 | — | | $19.90 | 1/17/2029 | — | — |
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| | 10/12/2018 | 15,000 | — | | $26.10 | 10/12/2028 | — | — |
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| | 5/12/2016 | 2,000 | — | | $148.00 | 5/12/2026 | — | — |
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| | 6/15/2015 | 375 | — | | $2,640.00 | 6/15/2025 | — | — |
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| Jarrod Longcor | 11/30/2023(1) | 166,700 | 333,300 | | $2.65 | 11/30/2033 | |
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| | 1/17/2023(1) | 184,010 | 103,990 | | $1.68 | 1/17/2033 | — | — |
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| | 1/25/2022(1) | 46,180 | 1,320 | | $5.50 | 1/25/2032 | — | — |
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| | 3/4/2021 | 45,000 | — | | $17.40 | 3/4/2031 | — | — |
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| | 2/3/2020 | 4,000 | — | | $27.10 | 2/3/2030 | — | — |
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| | 1/17/2019 | 3,000 | — | | $19.90 | 1/17/2029 | — | — |
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| | 10/12/2018 | 6,300 | — | | $26.10 | 10/12/2028 | — | — |
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| | 9/18/2017 | 250 | — | | $183.00 | 9/18/2027 | — | — |
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| | 7/15/2016 | 750 | — | | $293.00 | 7/15/2026 | — | — |
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| Chad J. Kolean | 11/30/2023(1) | 96,686 | 193,314 | | $2.65 | 11/30/2033 | |
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| | 1/17/2023(1) | 132,896 | 75,104 | | $1.68 | 1/17/2033 | — | — |
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| | 2/22/2022(2) | 10,000 | 5,000 | | $4.90 | 2/21/2032 | — | — |
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| (1) | These options are scheduled to vest one-third on the first anniversary of the grant date and in 24 equal monthly installments thereafter, subject to continuous employment with the Company through each vesting date. |
| (2) | These options are scheduled to vest annually in increments of one-third over three years from the date of grant. |
Pursuant to the terms of the option award agreements, options granted pursuant to the Amended and Restated 2015 Stock Incentive Plan and the 2021 Plan become fully vested upon a termination event within one year following a change in control, as defined in such plans. A termination event is defined as either termination of employment other than for cause or constructive termination resulting from a significant reduction in either the nature or scope of duties and responsibilities, a reduction in compensation or a required relocation.
Risks Related to Compensation Policies and Practices
When determining our compensation policies and practices, the Compensation Committee considers various matters relevant to the development of a reasonable and prudent compensation program, including whether the policies and practices are reasonably likely to have a material adverse effect on us. We believe that the mix and design of our executive compensation plans and policies do not encourage management to assume excessive risks and are not reasonably likely to have a material adverse effect on us.
Pay Versus Performance
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| · · Pay Versus Performance |
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| · · · · · · Average · · · · · · · |
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| | | | | | | Summary | | Average | | Value of | | |
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| | | | | | | Compensation | | Compensation | | Initial Fixed | | |
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| | | | | | | Table Total | | Actually Paid | | $100 | | |
| | | Summary | | Compensation | | for Non-PEO | | to Non-PEO | | Investment | | |
| | | Compensation | | Actually Paid | | Named | | Named | | Based On: | | |
| | | Table | | to | | Executive | | Executive | | Total | | Net Income |
| | | Total for PEO | | PEO | | Officers | | Officers | | Shareholder Return | | (Loss) |
| Year(1) | | ($)(2) | | ($)(3) | | ($)(2) | | ($)(4) | | ($)(5) | | ($) |
| 2024 | | 3,042,750 | | 1,321,211 | | 1,526,700 | | 708,983 | | $1.44 | | (44,581,446) |
| 2023 | | 1,965,140 | | 2,350,558 | | 1,235,760 | | 1,336,841 | | $13.32 | | (42,770,610) |
| 2022 | | 1,463,172 | | 146,850 | | 514,617 | | 294,040 | | $8.22 | | (31,792,618) |
| (1) | James V. Caruso, served as the Company’s principal executive officer (“PEO”) for the entirety of 2024, 2023 and 2023 and the Company’s other NEOs for the entirety of 2024, 2023 and 2022 were Jarrod Longcor and Chad J. Kolean. |
| (2) | Amounts reported in this column represent (i) the total compensation reported in the Summary Compensation Table for the applicable year in the case of Mr. Caruso and (ii) the average of the total compensation reported in the Summary Compensation Table for the applicable year for the Company’s NEOs reported for the applicable year other than the principal executive officer for such years. |
| (3) | Amounts reported in this column represent the compensation actually paid to Mr. Caruso as the Company’s President and Chief Executive Officer in the indicated fiscal years, based on his total compensation reported in the Summary Compensation Table for the indicated fiscal years and adjusted as shown in the table below: |
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| · · PEO |
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| · 2024 · 2023 · 2022 |
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| Summary Compensation Table - Total Compensation(a) | | $3,042,750 | | $1,965,140 | | $1,463,172 |
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| - Grant Date Fair Value of Stock Awards and Option Awards Granted in Fiscal Year(b) | | (2,214,000) | | (822,722) | | (616,697) |
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| +Fair Value at Fiscal Year-End of Outstanding and Unvested Option Awards Granted in Fiscal Year(c) | | 83,992 | | 1,148,400 | | 127,710 |
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| +Change in Fair Value of Outstanding and Unvested Option Awards Granted in Prior Fiscal Years(d) | | (388,965) | | 108,626 | | (430,237) |
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| +Fair Value at Vesting of Stock Awards and Option Awards Granted in Fiscal Year That Vested During Fiscal Year(e) | | 690,143 | | 69,462 | | 178,023 |
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| +Change in Fair Value as of Vesting Date of Option Awards Granted in Prior Fiscal Years For Which Applicable Vesting Conditions Were Satisfied During Fiscal Year(f) | | 139,727 | | (3,874) | | (84,783) |
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| - Fair Value as of Prior Fiscal Year-End of Option Awards Granted in Prior Fiscal Years That Failed to Meet Applicable Vesting Conditions During Fiscal Year(g) | | (32,436) | | (114,474) | | (490,338) |
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| = Compensation Actually Paid | | $1,321,211 | | $2,350,558 | | $146,850 |
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| (a) | Represents Total Compensation as reported in the Summary Compensation Table for the indicated fiscal year. |
| (b) | Represents the aggregate grant date fair value of the stock awards and option awards granted to Mr. Caruso during the indicated fiscal year, calculated using the same methodology as used in the Company’s financial statements under generally accepted accounting principles. |
| (c) | Represents the aggregate fair value as of the indicated fiscal year-end of Mr. Caruso’s outstanding and unvested option awards granted during such fiscal year, calculated using the same methodology as used in the Company’s financial statements under generally accepted accounting principles. |
| (d) | Represents the aggregate change in fair value during the indicated fiscal year of the outstanding and unvested option awards held by Mr. Caruso as of the last day of the indicated fiscal year, calculated using the same methodology as used in the Company’s financial statements under generally accepted accounting principles. |
| (e) | Represents the aggregate fair value at vesting of the stock awards and option awards that were granted to Mr. Caruso and vested during the indicated fiscal year, calculated using the same methodology as used in the Company’s financial statements under generally accepted accounting principles. |
| (f) | Represents the aggregate change in fair value, measured from the prior fiscal year-end to the vesting date, of each option award held by Mr. Caruso that was granted in a prior fiscal year and which vested during the indicated fiscal year, calculated using the same methodology as used in the Company’s financial statements under generally accepted accounting principles. |
| (g) | Represents the aggregate fair value as of the last day of the prior fiscal year of Mr. Caruso’s option awards that were granted in a prior fiscal year and which failed to meet the applicable vesting conditions in the indicated fiscal year, calculated using the same methodology as used in the Company’s financial statements under generally accepted accounting principles. |
| (4) | Amounts reported in this column represent the compensation actually paid to the Company’s NEOs other than Mr. Caruso in the indicated fiscal year, based on the average total compensation for such NEOs reported in the Summary Compensation Table for the indicated fiscal year and adjusted as shown in the table below: |
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| · · Other NEOs Average(a) |
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| · 2024 · 2023 · 2022 |
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| Summary Compensation Table - Total Compensation(b) | | $1,526,700 | | $1,235,760 | | $514,617 |
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| - Grant Date Fair Value of Stock Awards and Option Awards Granted in Fiscal Year(c) | | (971,700) | | (453,024) | | (132,258) |
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| +Fair Value at Fiscal Year-End of Outstanding and Unvested Option Awards Granted in Fiscal Year(d) | | 36,863 | | 545,600 | | 28,350 |
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| +Change in Fair Value of Outstanding and Unvested Option Awards Granted in Prior Fiscal Years(e) | | (186,868) | | 21,375 | | (61,221) |
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| +Fair Value at Vesting of Stock Awards and Option Awards Granted in Fiscal Year That Vested During Fiscal Year(f) | | 269,728 | | 10,771 | | 26,358 |
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| +Change in Fair Value as of Vesting Date of Option Awards Granted in Prior Fiscal Years For Which Applicable Vesting Conditions Were Satisfied During Fiscal Year(g) | | 49,799 | | (766) | | (12,048) |
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| - Fair Value as of Prior Fiscal Year-End of Option Awards Granted in Prior Fiscal Years That Failed to Meet Applicable Vesting Conditions During Fiscal Year(h) | | (15,539) | | (22,875) | | (69,758) |
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| = Compensation Actually Paid | | $708,983 | | $1,336,841 | | $294,040 |
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| (a) | See footnote 1 for the NEOs included in the average for each indicated fiscal year. |
| (b) | Represents the average Total Compensation as reported in the Summary Compensation Table for the reported NEOs in the indicated fiscal year. |
| (c) | Represents the average aggregate grant date fair value of the stock awards and option awards granted to the reported NEOs during the indicated fiscal year, calculated using the same methodology as used in the Company’s financial statements under generally accepted accounting principles. |
| (d) | Represents the average aggregate fair value as of the indicated fiscal year-end of the reported NEOs’ outstanding and unvested option awards granted during such fiscal year, calculated using the same methodology as used in the Company’s financial statements under generally accepted accounting principles. |
| (e) | Represents the average aggregate change in fair value during the indicated fiscal year of the outstanding and unvested option awards held by the reported NEOs as of the last day of the indicated fiscal year, calculated using the same methodology as used in the Company’s financial statements under generally accepted accounting principles. |
| (f) | Represents the average aggregate fair value at vesting of the stock awards and option awards that were granted to the reported NEOs and vested during the indicated fiscal year, calculated using the same methodology as used in the Company’s financial statements under generally accepted accounting principles. |
| (g) | Represents the average aggregate change in fair value, measured from the prior fiscal year-end to the vesting date, of each option award held by the reported NEOs that was granted in a prior fiscal year and which vested during the indicated fiscal year, calculated using the same methodology as used in the Company’s financial statements under generally accepted accounting principles. |
| (h) | Represents the average aggregate fair value as of the last day of the prior fiscal year of the reported NEOs’ option awards that were granted in a prior fiscal year and which failed to meet the applicable vesting conditions in the indicated fiscal year, calculated using the same methodology as used in the Company’s financial statements under generally accepted accounting principles. |
| (5) | Pursuant to rules of the SEC, the comparison assumes $100 was invested on December 31, 2021, in our common stock. Historic stock price performance is not necessarily indicative of future stock price performance. |
2024 Director Compensation
The following table sets forth certain information about the compensation of our non-employee directors who served during the year ended December 31, 2024:
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| · Director · Option · |
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| · · · · Fees · · Awards · · · |
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| Name | | Year | | ($)(1) | | ($)(2) | | Total ($) | |
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| Asher Chanan-Khan, M.B.B.S., M.D. | | 2024 | | | $60,000 | | | $148,200 | | $208,200 |
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| Frederick W. Driscoll | | 2024 | | | 60,000 | | | 148,200 | | 208,200 |
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| Stefan D. Loren, Ph.D. | | 2024 | | | 60,000 | | | 148,200 | | 208,200 |
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| John Neis | | 2024 | | | 60,000 | | | 148,200 | | 208,200 |
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| Douglas J. Swirsky | | 2024 | | | 90,000 | | | 222,300 | | 312,300 |
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| (1) | Director fees consist of annual cash fees for service. |
| (2) | Granted on December 15, 2023, subject to stockholder approval of an amendment to the 2021 Plan at the 2024 annual meeting of stockholders. Because stockholder approval was received in 2024, these stock option awards are considered granted in 2024 under ASC 718 and are reflected as 2024 compensation in the 2024 Director Compensation Table. These stock options have an exercise price of $2.58 per share and fully vest on the first anniversary of the grant date, subject to continued service through applicable vesting date. The reported amounts represent the aggregate grant date fair value computed in accordance with ASC 718. All assumptions made regarding the valuation of equity awards can be referenced in Note 7 in the Notes to Restated Consolidated Financial Statements included in this prospectus. |
During 2024, we paid each of our non-employee directors a quarterly cash fee of $15,000 ($22,500 for Mr. Swirsky). In addition, in December 2023, we granted to each non-employee director stock options to purchase 60,000 shares (90,000 shares for Mr. Swirsky), which were subject to the approval of an amendment to the 2021 Plan at the 2024 annual meeting of stockholders. Mr. Swirsky receives additional cash remuneration and option awards for his service as Chairman of the Board of the Company. We reimbursed directors for reasonable out-of-pocket expenses incurred in attending Board and committee meetings and undertaking certain matters on our behalf. Directors who are our employees do not receive additional fees for their service as directors.
The aggregate number of option awards outstanding as of December 31, 2024, for each non-employee director was as follows:
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| | Stock |
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| · · Options |
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| Name · · Outstanding |
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| Asher Chanan-Khan, M.B.B.S., M.D. | 100,600 |
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| Frederick W. Driscoll | 107,650 |
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| Stefan D. Loren, Ph.D. | 107,885 |
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| John Neis | 107,885 |
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| Douglas J. Swirsky | 161,925 |
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Clawback Policy
Under the Sarbanes-Oxley Act, in the event of misconduct that results in a financial restatement that would have reduced a previously paid incentive amount, we can recoup those improper payments from our executive officers. The SEC also recently adopted rules which direct national stock exchanges to require listed companies to implement policies intended to recoup bonuses paid to executives if we are found to have misstated its financial results. We have adopted our Executive Compensation Clawback Policy (the “Clawback Policy”) in order to comply with the final clawback rules adopted by the SEC under the Rule, and the listing standards, as set forth in the Nasdaq Listing Rule 5608 (the “Final Clawback Rules”).
The Clawback Policy provides for the mandatory recovery of erroneously awarded incentive-based compensation from our current and former executive officers as defined in the Rule (“Covered Officers”) in the event that we are required to prepare an accounting restatement, in accordance with the Final Clawback Rules. The recovery of such compensation applies regardless of whether a Covered Officer engaged in misconduct or otherwise caused or contributed to the requirement of an accounting restatement. Under the Clawback Policy, our board of directors may recoup from the Covered Officers erroneously awarded incentive compensation received within a lookback period of the three completed fiscal years preceding the date on which we are required to prepare an accounting restatement. The foregoing description of the Clawback Policy does not purport to be complete and is qualified in its entirety by the terms and conditions of the Clawback Policy, a copy of which is attached hereto as Exhibit 97 and is incorporated herein by reference.
Timing of Grants of Options
We do not grant option awards in anticipation of the release of material nonpublic information and we donot time the release ofmaterial nonpublic information based on option award grant dates or for the purpose of affecting the value of executive compensation. In addition, we do not take material nonpublic information into account when determining the timing and terms of such awards. In fiscal year 2024, we did not grant option awards to our named executive officers during the time period outlined in Item 402(x) of Regulation S-K