OptimizeRx Corp

UNITED STATES

SECURITIES AND EXCHANGE COMMISSION

Washington, D.C. 20549

SCHEDULE 14A

Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934

(Amendment No. )

Filed by the Registrant☒

Filed by a Party other than the Registrant☐

Check the appropriate box:

OPTIMIZERX CORPORATION

(Name of Registrant as Specified In Its Charter)

Not Applicable

(Name of Person(s) Filing Proxy Statement, if other than the Registrant)

Payment of Filing Fee (Check all boxes that apply):

Notice of Annual Meeting of Shareholders

Date and Time Tuesday, June 9, 2026, at 10:00 AM (EDT) Meeting Access Live Audio Webcast: www.virtualshareholdermeeting.com/OPRX2026 Record Date April 10, 2026 Items of Business • Proposal No. 1: Election as director, each of the seven persons named in the accompanying proxy statement as our Board of Directors’ nominees to serve on the OptimizeRx Board of Directors until the 2027 Annual Meeting of Shareholders and until his or her successor is duly elected and qualified, or until his or her earlier death, resignation, or removal.

• Proposal No. 2: Advisory (non-binding) approval of the compensation of OptimizeRx’s named executive officers.

• Proposal No. 3: Approval of an amendment to the OptimizeRx Corporation 2021 Equity Incentive Plan (the “2021 Equity Plan”) to increase the aggregate number of shares of the Company’s common stock (“Common Stock”) available for awards by 1,000,000 shares to 5,450,000 shares.

• Proposal No. 4: Approval of an amendment to the 2021 Equity Plan to adopt an evergreen provision providing for an automatic annual increase in the shares of Common Stock available for issuance under the 2021 Equity Plan.

• Proposal No. 5: Ratification of Grant Thornton LLP as OptimizeRx’s independent registered public accounting firm for the fiscal year ending December 31, 2026.

• Consideration of any other business properly brought before the Annual Meeting or any postponements or adjournments thereof.

This year’s Annual Meeting of Shareholders will be an entirely virtual meeting conducted via live webcast. The Annual Meeting format will be a live audio webcast where you can view presentation materials made available online. There will be no physical in-person meeting. Additional information regarding attending the Annual Meeting online, voting your shares, and submitting questions in advance of the Annual Meeting can be found in the accompanying proxy statement.

Eligibility to Vote

Only shareholders of record, as of the close of business on April 10, 2026, are entitled to notice of and to vote at the Annual Meeting and any postponements or adjournments thereof.

This Notice of Annual Meeting of Shareholders, the accompanying proxy statement, form of proxy and the Annual Report on Form 10-K for the fiscal year ended December 31, 2025, which is not a part of the proxy solicitation materials, are being distributed and made available to our shareholders starting on or about April 30, 2026.

Your vote is important. Whether or not you attend the meeting, we urge you to vote promptly.

Important Notice Regarding the Availability of Proxy Materials for the Annual Meeting of Shareholders to be Held on June 9, 2026

This Notice of Annual Meeting of Shareholders, the accompanying proxy statement and the Annual Report on Form 10-K for the fiscal year ended December 31, 2025 are available atwww.proxyvote.com.