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Raphael Pharmaceutical Inc.

For the period ended Dec 31, 2025. Filed Mar 31, 2026.

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A company's yearly report to the SEC, with audited financial statements. It is the fullest account a company gives of its business, its finances and the risks it sees.

FY2025 · Filed Mar 31, 2026

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Contents

Notes to Consolidated Financial Statements

NOTE 1:-GENERAL
a.Raphael Pharmaceutical Inc (formerly Easy Energy, Inc.) (“Raphael”, or the “Company”) was incorporated under the laws of the State of Nevada on May 17, 2007. The Company is headquartered in Tel Aviv-Jaffa, Israel. From April 1, 2011 until December 31, 2019, the Company was not active. On October 8, 2020, the Company and its stockholders entered into a Share Exchange Agreement (the “Share Exchange”) with an Israeli pharmaceutical company (“Raphael”), according to which, among other matters, all shareholders of Raphael will sell and convey the entire holdings in Raphael to the Company such that following the Share Exchange, the shareholders of Raphael will hold 90% of the issued and outstanding common stock of the Company, and the existing shareholders of the Company will hold the remaining 10% of the issued and outstanding common stock. On May 14, 2021, the Company’s board of directors (the “Board”) and stockholders approved a 1-for-100 reverse split of the Company’s common stock, which was implemented and became effective as of May 14, 2021. The reverse split combined each one hundred (100) shares of the Company’s issued and outstanding Common stock into one share of common stock. No fractional shares were issued in connection with the reverse split, and any fractional shares resulting from the reverse split were rounded up to the nearest whole share. On May 14, 2021, Raphael and the Company, completed the Share Exchange pursuant to which 9,459,253 common stock were issued to the shareholders of Raphael so that they became the holders of 90% of the issued and outstanding common stock of the Company immediately after the Share Exchange while the Company’s shareholders hold, following the Share Exchange, 1,051,028 common stock which represents 10% of the Company. On May 19, 2021, as agreed by the parties to the Share Exchange, the Company changed its name to Raphael Pharmaceutical Inc. Following such Share Exchange, Raphael’s activities are the sole activities of the Company. The Share Exchange was accounted for as a reverse recapitalization which is outside the scope ASC 805, “Business Combinations” (“ASC 805”), as the Company, the legal acquirer, is considered a non-operating public shell, and is therefore not a business as defined in ASC 805. As the shareholders of Raphael received the largest ownership interest in the Company, Raphael was determined to be the “accounting acquirer” in the Share Exchange. As a result, the historical financial statements of the Company were replaced with the financial statement of Raphael for all periods presented. The Company’s common stock began public trading on the over the counter market in the U.S. in January 2023 under the symbol “RAPH”.
b.Going concern and management plans

The accompanying consolidated financial statements have been prepared on a going-concern basis, which contemplates the realization of assets and satisfaction of liabilities in the normal course of business. Since its inception, the Company has devoted substantially all of its efforts to research and development, clinical trials, and raising capital. The Company is still in its development and pre-clinical stage and has not yet generated revenues. The extent of the Company’s future operating losses and the timing of becoming profitable are uncertain. As of December 31, 2025, the Company’s accumulated deficit was $10,168 the net loss for the year then ended was $1,279 and the net cash used in operating activities was $210.

NOTE 1:-GENERAL (Cont.)

The Company has funded its operations to date primarily through equity financing and loans including from related parties.

Additional funding will be required to complete the Company’s research and development and clinical trials, to attain regulatory approvals, to begin the commercialization efforts of the Company’s product and to achieve a level of sales adequate to support the Company’s cost structure.

Management’s plans include, but are not limited to, raising capital in the United States. There can be no assurance that it will be able to successfully raise additional financing, including in a public offering, or obtain additional financing on a timely basis or on terms acceptable to the Company, or at all.

Management expects that the Company will continue to generate losses from the development, clinical development and regulatory activities of its product, which will result in negative cash flow from operating activity. This has led management to conclude that substantial doubt about the Company’s ability to continue as a going concern exists in the event that additional funding does not occur. If such sufficient financing is not received timely, the Company will not have sufficient cash flows and liquidity to finance its business operations as currently contemplated and would then need to pursue a plan to license its assets, seek to be acquired by another entity, cease operations and/or seek bankruptcy protection. The Company’s financial statements do not reflect any adjustments that might result from the outcome of this uncertainty.

NOTE 2:-SIGNIFICANT ACCOUNTING POLICIES
a.Basis of presentation:

The consolidated financial statements have been prepared in accordance with accounting principles generally accepted in the United States (“U.S. GAAP”).

The consolidated financial statements include the accounts of the Company and its subsidiary. Intercompany accounts and transactions have been eliminated upon consolidation.

b.Use of estimate in preparation of the consolidated financial statements:

The preparation of consolidated financial statements in conformity with U.S. GAAP requires management to make estimates, judgments and assumptions that affect the amounts reported in the consolidated financial statements and accompanying notes. The Company evaluates on an ongoing basis its assumptions. The Company’s management believes that the estimates, judgments and assumptions used are reasonable based upon information available at the time they are made. These estimates, judgments and assumptions can affect the reported amounts of assets and liabilities and disclosure of contingent assets and liabilities at the dates of the consolidated financial statements, and the reported amounts of expenses during the reporting periods. Actual results could differ from those estimates.

NOTE 2:-SIGNIFICANT ACCOUNTING POLICIES (Cont.)
c.Consolidated financial statements in United States dollars:

The Company’s functional currency is the U.S. dollar (“dollar” or “$”) since the dollar is the currency of the primary economic environment in which the Company has operated and expects to continue to operate in the foreseeable future. Transactions and balances denominated in dollars are presented at their original amounts. Transactions and balances denominated in currencies other than dollars have been re-measured to dollars. All transaction gains and losses from re-measurement of monetary balance sheet items denominated in currencies other than dollars are reflected in the statements of comprehensive loss as financial expenses, net.

d.Cash and cash equivalents:

Cash equivalents are short-term highly liquid investments that are readily convertible to cash with original maturities of three months or less as of the date acquired and that are exposed to insignificant risk of change in value.

e.Fair value measurements:

The carrying values of Company’s financial assets and liabilities, including cash and cash equivalents, other current assets, related parties, accounts payable and accrued expenses approximate their fair value due to the short-term maturity of these instruments.

f.Research and development expenses:

Research and development expenses are charged to the statements of comprehensive loss as incurred.

g.Income taxes:

The Company accounts for income taxes in accordance with ASC 740, “Income Taxes”. ASC 740 prescribes the use of the liability method whereby deferred tax assets and liability account balances are determined based on differences between financial reporting and tax bases of assets and liabilities and are measured using the enacted tax rates and laws that will be in effect when the differences are expected to reverse. Valuation allowances in respect of deferred tax assets are provided for, if necessary, to reduce deferred tax assets to amounts more likely than not to be realized. As of December 31, 2025, and 2024, the Company had a full valuation allowance on its deferred tax assets.

h.Basic and diluted net loss per share:

Earnings or loss per share (“EPS”) is the amount of earnings attributable to each share of common stock. For convenience, the term is used to refer to either earnings or loss per share. EPS is computed pursuant to ASC 260-10-45. Pursuant to ASC 260-10-45-10 through 260-10-45-16 Basic EPS is computed by dividing income available to common stockholders (the numerator) by the weighted-average number of common shares outstanding (the denominator) during the period. Loss available to common stockholders shall be computed by deducting both the dividends declared in the period on preferred stock (whether or not paid) from loss from operating loss (if that amount appears in the statements of comprehensive loss) and also from net loss.

NOTE 2:-SIGNIFICANT ACCOUNTING POLICIES (Cont.)

The computation of diluted EPS is similar to the computation of basic EPS except that the denominator is increased to include the number of additional common shares that would have been outstanding if the dilutive potential common stock had been issued during the period to reflect the potential dilution that could occur from common shares issuable through contingent shares issuance arrangement, stock options or warrants.

The net loss per share and the weighted average number of shares used in computing basic and diluted net loss per share is as follows:

For the Year Ended December 31,
20252024
Numerator:
Net loss applicable to common stockholders$(1,279)$(1,519)
Denominator:
Number of shares of common stock used in computing basic and diluted net loss per share19,551,71918,674,136
Net loss of shares of common, basic and diluted$(0.07)$(0.08)
i.Leases

In February 2016, the Financial Accounting Standards Borad (“FASB”) issued ASU 2016-02, Leases (Topic 842) (“ASU 2016-02”). ASU 2016-02 requires lessees to recognize their leases contracts as assets and liabilities in the consolidated financial statements. Furthermore, the ASU requires the Company to continue recognizing expenses but recognize expenses on their statements of comprehensive loss in a manner similar to current lease accounting. The amendments in this ASU are effective January 1, 2019. In July 2018, the FASB issued ASU 2018-11, Leases - Targeted Improvements, to allow a company to elect an optional modified retrospective transition method that applies the new lease requirements through a cumulative-effect adjustment in the period of adoption.

Effective January 2019, the Company adopted the new lease accounting standard. The Company elected to apply the practical expedients permitted under the transition guidance within the new standard. As such, there was no impact on the Company’s consolidated financial statements as a result of adopting ASU 2016-02.

NOTE 2:-SIGNIFICANT ACCOUNTING POLICIES (Cont.)
j.Recently adopted accounting pronouncements:

In November 2023, the FASB issued ASU 2023-07, Segment Reporting (Topic 280), Improvements to Reportable Segment Disclosures, which expands public entities’ segment disclosures primarily by requiring disclosure of significant segment expenses that are regularly provided to the chief operating decision maker and included within each reported measure of segment profit or loss, an amount and description of its composition for other segment items. The guidance is in effect for the Company for annual periods beginning January 1, 2024 and will be in effect for the interim periods beginning January 1, 2025. Early adoption is permitted. The Company has adopted this standard for the fiscal year 2024 annual financial statements and interim financial statements thereafter and has applied this standard retrospectively for all prior periods presented in the financial statements. See Note 10 – Segment Reporting for further information.

In December 2023, the FASB issued ASU 2023-09, Income Taxes (Topic 740), Improvements to Income Tax Disclosures, which requires disaggregated information about the effective tax rate reconciliation as well as information on income taxes paid. The guidance will be in effect for the Company for annual periods beginning January 1, 2025, with early adoption permitted.

k.Recently issued accounting pronouncements not yet adopted

In November 2024, the FASB issued ASU 2024-03 “Income Statement (Topic 220): Reporting Comprehensive Income - Expense Disaggregation Disclosures” (“ASU 2024-03”), which requires more detailed information about specified categories of expenses presented on the face of the income statement, in addition to disclosures about selling expenses. ASU 2024-03 will be in effect for fiscal years beginning after December 15, 2026, with early adoption permitted. The amendment may be applied either prospectively to financial statements issued for reporting periods after the effective date or retrospectively to all prior periods presented in the financial statements. The Company is currently evaluating ASU 2024-03 to determine the impact it may have on its consolidated financial statements and related disclosures.

In January 2025, the FASB issued ASU 2025-01,Income Statement—Reporting Comprehensive Income—Expense Disaggregation Disclosures (Subtopic 220-40), which revises the effective date of ASU 2024-03 (on disclosures about disaggregation of income statement expenses) “to clarify that all public business entities are required to adopt the guidance in annual reporting periods beginning after December 15, 2026, and interim periods within annual reporting periods beginning after December 15, 2027.” Entities within the ASU’s scope are permitted to early adopt the ASU. This Update is not expected to have a significant impact on the Company’s financial statements.

NOTE 3:-OTHER CURRENT ASSETS
As of December 31,
20252024
Receivables from governmental authorities22
Prepaid expenses44
$6$6
NOTE 4:-OTHER ACCOUNTS PAYABLE AND ACCRUED EXPENSES
As of December 31,
20252024
Account payables$163$125
Accrued expenses343375
$506$500
NOTE 5:-SHORT TERM LOAN

On December 24, 2024, the Company received a short-term loan from certain lender in a total of NIS 150 thousand ($41, based on the NIS-USD exchange rate on December 24, 2024, the date the agreement was signed). The loan was originally repayable within four months and included a risk premium of NIS 12 thousand exclusive of value-added tax (VAT). Since the Company did not repay the loan within the original timeframe, the total interest and penalties incurred amounted to NIS 54 thousand.

During the year ended December 31, 2025, the Company repaid an aggregate amount of NIS 96.9 thousand. As of December 31, 2025, the remaining balance of the loan, including accrued interest, is NIS 107.1 thousand ($34, based on the NIS-USD exchange rate on December 31, 2025). and is included within short-term credit from a related party in the Consolidated Balance Sheets.

The Company’s chief executive officer (“CEO”) and chief financial officer (“CFO”) are guarantees for the repayment of the loan.

NOTE 6:-CONTINGENT LIABILITIES AND COMMITMENTS
a.Rambam research agreement

In October 2022, the Company and Rambam signed a supplement to the Research Agreement, according to which the objective of the new study will be to identify a novel cannabinoid based patentable formulation to treat RA diseases. The total cost of the new study will be $800 + $160 (overhead) + VAT (which consist of $700 + VAT pre-clinical lab research cost, $120 + VAT Mouse model for systemic inflammation and $140 + VAT Mouse model for Rheumatoid Arthritis). The Company’s payments will be according to the payment schedule stipulated in the supplement and will begin in May 2023.

NOTE 6:-CONTINGENT LIABILITIES AND COMMITMENTS (Cont.)

As of December 31, 2025, the remaining balance of the loan, including accrued interest, is NIS 949.7 thousand +VAT ($297.7, based on the NIS-USD exchange rate on December 31, 2025) and is included within other accounts payable and accrued expenses in the Consolidated Balance Sheets.

b.Way of Life Cannabis research agreement

In October 2020, Raphael entered into an engagement agreement with Way of Life Cannabis Ltd. (“WOLC”), pursuant to which, subject to its completing the Share Exchange with Easy Energy, Raphael will be provided with up to 15 liters of CBD oil, from a strain of cannabis during a term of 18 months, to be provided in two to three deliveries of between one to seven liters of CBD oil.

In accordance with Raphael’s agreement with WOLC, Raphael has agreed to issue to certain persons affiliated with WOLC 3% of Raphael’s issued and outstanding share capital as of the date of the Share Exchange, to be provided in three equal issuances; provided, however, that such persons may elect to receive a cash payment of $100 instead of any one issuance of Raphael’s shares. In addition to the issuance of shares, Raphael has also agreed to pay WOLC a royalty fee equal to 15% of the net royalties generated from sales of Raphael’s pharmaceutical drug products that are developed at Rambam hospital in Israel. In February 2023, the Company and WOLC signed an appendix to the research agreement, according to which the parties agreed that WOLC provided to the Company 12 out of 15 liters of CBD oil, from a strain of cannabis and the Company will transfer to WOLC the remaining stock per research agreement. In addition, WOLC will transfer the remaining 3 liters of CBD oil to the Company upon Company’s request.

On July 27, 2022, the Company issued 100,500 shares of common stock to WOLC in connection with the engagement agreement. The value of such issued shares was based on the value of the service provided, which amounted to $100. In June 2023, the Company issued the remaining 201,000 shares of common stock to WOLC in connection with the services agreement dated October 2020. The value of the shares issued was based on the value of the service provided, which amounted to $200.

c.Service agreement with executive officers:

During fiscal year 2025, we had the following written agreements with our executive officers, including the Company’s CEO, CFO and Chief Technology Officer, who are also members of the Board.

●The Company’s CEO provides services to the Company pursuant to a management and operations agreement between the Company and Sheffa Enterprises, Inc., a New Jersey corporation. Since January 1, 2024, we have paid the CEO a monthly fee of $20,000 for his services. On March 3, 2025, we entered into a new management and operations agreement with the CEO substantially on the same terms as the agreement described above, effective as of January 1, 2025, The warrants to purchase up to 1,000,000 shares of Common Stock, which were previously issued to Mr. Pilo, at an exercise price of $1.12 per share, were expired unexercised on December 31, 2025.. The management and operations agreement which was set to expire on December 31, 2025, was extended until December 31, 2026 on December 27, 2025, effective as of January 1, 2026

The Company may terminate the management and operations agreement prior to the expiration of its term upon 120 days advance notice and the payment of a termination fee equal to the lesser of (i) $360,000, or (ii) the monthly fees payable through the expiration of its term. Furthermore, as disclosed in the agreement, we have undertaken to indemnify Sheffa Enterprises, Inc. against and in respect of any and losses arising out of or due to the operation of the business by Raphael Israel, its affiliates, agents, servants and/or employees.

NOTE 6:-CONTINGENT LIABILITIES AND COMMITMENTS (Cont.)
●The CFO provides services to the Company pursuant to an operations agreement between the Company, Model Engineering &Investments SRL, a Romanian Company, and Guy Ofir. Since January 1, 2023, we have paid the CFO a monthly fee of $12,000. In addition, we granted Mr. Ofir 1,000,000 restricted shares of Common Stock and warrants to purchase up to 1,000,000 shares of Common Stock, at an exercise price of $1.00 per share, which expired unexercised on December 31, 2025. On March 3, 2025, we entered into a new operations agreement with our Chief Financial Officer, substantially on the same terms as the agreement described above, effective as of January 1, 2025. The operations agreement, which was set to expire on December 31, 2025, was extended until December 31, 2026 on December 27, 2025, effective as of January 1, 2026. The Company may terminate the operations agreement prior to the expiration of its term upon 120 days advance notice and the payment to Mr. Ofir of a termination fee equal to the lesser of (i) $120,000, or (ii) the monthly fees payable through the expiration of its term.
●The Company’s Chief Technology Officer provides services to the Company pursuant to a service agreement, by and between the Company and Dr. Igal Louria Hayon. Pursuant to the terms thereof Dr. Hayon provides consulting services the Company to engage with an array of science consultants and to coordinate collaborations with hospitals on medical cannabis research. Pursuant to such agreement, we agreed to pay the Chief Technology Officer 15% of the Company’s net royalty’s income from worldwide sales of any of the Company’s cannabis-based medical indications treating COVID-19. Pursuant to Dr. Hayon’s service agreement, in the event we will apply for any clinical trial of cannabis-based treatment or will begin any other new cannabis related research, the Corporation will grant Dr. Hayon warrants to purchase up to 350,000 shares of Common Stock at an exercise price of $0.01. On May 1, 2024, the milestone was met and the Company granted to Dr. Igal Louria Hayon warrants to purchase up to 350,000 shares of Common Stock of the Company at an exercise price of $0.01. The warrants were exercised in November 2025. On March 3, 2025, we entered into a new service agreement with the Company’s Chief Technology Officer, substantially on the same terms as the agreement described above, effective as of January 1, 2025. Pursuant to such service agreement, we agreed to pay the Chief Technology Officer a monthly fee of $24,000 and to reimburse him with certain expenses related to his scientific work. On December 27, 2025, the company extended such service agreement with our Chief Technology Officer, effective as of January 1, 2026 and until December 31, 2027. Pursuant to the extension to such service agreement, we agreed to pay our Chief Technology Officer a monthly fee of $12,000 and to reimburse him with certain expenses related to his scientific work. The Company may terminate the service agreement prior to the expiration of its term upon 120 days advance notice and the payment to Dr. Hayon of a termination fee equal to the monthly fees payable through the expiration of its term.
NOTE 7:-STOCKOLDERS’ EQUITY
a.In January 2023, the Company issued 255,750 shares of common stock following certain share purchase agreements dated November and December 2022.
NOTE 7:-STOCKOLDERS’ EQUITY (Cont.)
b.On January 8, 2023, certain investor of the Company and the Company signed an agreement to raise $250 and to issue 250,000 shares of common stock and 100,000 warrants to purchase common stock at an exercise price of $1.13 per share following the exercise of an option for additional investment. The warrants are exercisable until April 30, 2024. In January 2023, the investor and the Company agreed to raise $117 out of the $250 investment. As a result, the Company received $117 and issued 117,000 shares of common stock and the issuance of 100,000 warrants to purchase common stock of the Company were cancelled.
c.From March through June, 2023, certain investors of the Company and the Company signed an agreement to raise $198 and to issue 170,378 shares of common stock. The shares were issued in April 2023.
d.In May 2023, certain investor of the Company and the Company signed an agreement to exercise investors warrants into Company’s common stock. In May 2023, the investor transferred $123.
e.In June 2023, the Company issued 201,000 shares of common stock to Way of Life Cannabis Ltd., or WOLC, in connection with the services agreement dated October 2020. The value of the shares issued was based on the value of the service provided and amounted to $200.
f.From July through September, 2023, certain investors of the Company exercised their warrants into shares and as such, the Company received $480 (including $123 which was received in May 2023) and issued 1,454,250 shares of common stock.
g.In September 2023, certain investor of the Company and the Company signed an agreement to raise $50 and to issue 100,000 shares of common stock.
h.In September 2023, certain investor of the Company and the Company signed an agreement to exercise investors warrants into Company’s common stock for an amount of $180. In September and December 2023, the investor transferred $180 and the Company issued 180,000 shares.
i.In November 2023, certain investor of the Company and the Company signed an investment agreement according to which the investors transferred $116 and the Company issued 200,500 shares.
j.In December 2023, certain investors of the Company and the Company signed an agreement to exercise investors warrants into Company’s common stock for an amount of $100. In December 2023, the Company issued 200,000 shares. As of December 31, 2023, the consideration for the warrant exercise above was recorded as receivables from issuance of shares.
k.In January 2024, the Company and certain investors signed an investment agreement according to which the investors transferred $80 and the Company issued 58,500 shares.
l.In January 2024, the Company signed an agreement to raise $100 and to issue 100,000 shares of common stock and 100,000 warrants to purchase common stock at an exercise price of $1 per share to certain investor of the Company. The warrants were exercisable until December 31, 2024.
m.In January 2024, the Company received $100 from certain shareholder as part of shareholders’ warrants exercise which occurred in December 2023.
NOTE 7:-STOCKOLDERS’ EQUITY (Cont.)
nIn May 2024, the Company issued 350,000 shares in connection with service agreement with certain service provider. There is no requisite service period for this grant. The fair value of the warrants granted was $347 using the Black-Scholes-Merton option pricing model using the following assumptions:
Share price$1
Dividend yield0%
Risk-free interest rate4.96%
Expected term (in years)2
Volatility0%
Exercise price$1

Volatility assumed 0% due to lack of market trading of the company share

s.In May 2024, the Company signed an agreement to raise 350,000 warrants to purchase common stock at an exercise price of $0.01 per share to certain investor of the Company.
o.In January 2025, certain investor of the Company and the Company signed an investment agreement according to which the investors transferred $55 and the Company issued 115,000 shares and 55,000 warrants to purchase common stock at an exercise price of $1.00 per share. The warrants will expire on July 15, 2026.
p.In January 2025, certain investor of the Company and the Company signed an investment agreement according to which the investors transferred $50 and the Company issued 200,000 shares.
q.In March 2025, The CEO of the Company and the Company signed an investment agreement according to which the CEO transferred $100 and the Company issued 200,000 shares and 100,000 warrants to purchase common stock at an exercise price of $1.00 per share. The warrants will expire on July 15, 2026.
r.In March 2025, certain investor of the Company and the Company signed an investment agreement according to which the investors transferred $25 and the Company issued 50,000 shares and 10,000 warrants to purchase common stock at an exercise price of $1.00 per share. The warrants will expire on March 15, 2026. There is no requisite service period for this grant. The fair value of the shares granted was $175 using the share price of other investor at the time. The fair value of the warrants granted was $22 using the Black-Scholes-Merton option pricing model using the following assumptions:
Share price$0.44
Dividend yield0%
Risk-free interest rate3.99%
Expected term (in years)1.75
Volatility80.05%
Exercise price$1
s.In March, 2025, the Company entered into a service agreement with Mr. Ajay Kumar Dhadha, pursuant to which Mr. Dhadha will serve as a member of our Board and as chairman of the Board. Pursuant to the service agreement, on March 5, 2025, the Company granted Mr. Dhadha 350,000 restricted shares of the Company’s Common Stock and warrants to purchase up to 250,000 shares of Common Stock at an exercise price of $1.00 per share, with a total value of $22. The warrants expired on December 31, 2026.
NOTE 7:-STOCKOLDERS’ EQUITY (Cont.)
t.In March 2025, certain investor of the Company and the Company signed an investment agreement according to which the investors transferred $10 and the Company issued 10,000 shares and 5,000 warrants to purchase common stock at an exercise price of $2.50 per share. The warrants will expire on March 15, 2026.
u.In March 2025, the Company entered into a service agreement with Mr. Eliya Yehuda, pursuant to which Mr. Yehuda will serve as a member of our Board. Pursuant to the service agreement, on March 10, 2025, the Company granted Mr. Yehuda warrants to purchase up to 200,000 shares of Common Stock at an exercise price of $1 per share, with a total value of $9. The warrants will expire on March 10, 2026. There is no requisite service period for this grant. The fair value of the warrants granted was $9 using the Black-Scholes-Merton option pricing model using the following assumptions:
Share price$0.44
Dividend yield0%
Risk-free interest rate3.99%
Expected term (in years)1
Volatility80.05%
Exercise price$1
v.In July, 2025, the Company entered into a service agreement with Mr. Zvi Laufer, pursuant to which Mr. Laufer will serve as a member of our Board. Pursuant to the service agreement, on July 31, 2025, the Company granted Mr. Laufer warrants to purchase up to 300,000 shares of Common Stock at an exercise price of $0.75 per share, with a total value of $39. The warrants will expire on July 31, 2027. There is no requisite service period for this grant. The fair value of the warrants granted was $9 using the Black-Scholes-Merton option pricing model using the following assumptions:
Share price$0.44
Dividend yield0%
Risk-free interest rate3.94%
Expected term (in years)2
Volatility80.05%
Exercise price$0.75
w.In December 2025, certain investor of the Company and the Company signed an investment agreement according to which the investors transferred $110 and the Company issued 200,000 shares.
x.On November 11, 2025, Mr. Igal Luria Hayon exercised 350,000 warrants that were issued to him in May 2024 and transferred $4 to the company according to the exercise price of $0.01 per warrant.

The following table summarizes information regarding outstanding warrants to purchase the Company’s ordinary shares as of December 31, 2025:

Issuance dateNumber of outstanding WarrantsExercise price per warrant
January 16, 202555,000$1
March 5, 2025250,000$1
March 10, 2025200,000$1
March 21, 20255,000$2.5
March 21, 202510,000$1
July 7, 2025100,000$1
July 31, 2025300,000$0.75
NOTE 7:-STOCKOLDERS’ EQUITY (Cont.)
Number of warrantsWeighted average exercise price
Outstanding at December 31, 2023$2,307,000$1.07
Grants350,0000.01
Exercised-
Expired(307,000)1.12
Outstanding at December 31, 20242,350,0000.9
Grants920,0000.93
Exercised350,0000.01
Expired2,000,0001.06
Outstanding at December 31, 2025920,0000.93

Significant assumptions used to estimate the fair value of share-based compensation awards:

Share priceThe price at the grant date
Dividend yieldThe company did not distribute dividends and do not expect to distribute in the forecasted future.
Risk-free interest rateTreasury bonds interest rates for the equivalent period time
VolatilityDue to lack of trading the information of the industry market was used. We do not use different volatility method.

The weighted-average grant-date fair value of stock based compensation are:

20242025
Warrants$347$25
shares-$175

There are no other grants of shares or warrants authorized to be issued for awards. Each equity grant is approved separately.

NOTE 8:-RELATED PARTIES BALANCES AND TRANSACTIONS
A.Balances

The following related party payables are included in accounts payable and accrued expenses.

As of December 31,
20252024
Payables to related party - Officers (*)946228
Short-term credit from a related party (|**)34
980228
(*)Relates to the Company’s CEO, CFO, and Chief Technology Officer’s services and payments on behalf of the Company.
(**)Relates to a director, who was appointed during the first quarter of 2025. The Company’s CEO and CFO are guarantees for the repayment of the loan.
NOTE 8:-RELATED PARTIES BALANCES AND TRANSACTIONS (Cont.)

The Company’s CEO and CFO are guarantees for the repayment of the loan (see note 5).

B.Transactions
Year ended December 31,
20252024
Consulting services (*)528240
Stock-based compensation245350
CFO fee (**)144144
Interest Short-term credit from a related party17
934734
(*)Including salary expenses to the Company’s CEO and CFO. For further details on the consulting agreement with Company’s CEO, refer to Note 6d.
(**)Including legal services provided to Company’s subsidiary by Company’s CFO with respect to an agreement between the Company and its CFO.
NOTE 9:-TAXES ON INCOME

Income tax rates applicable to the Company in 2025 and 2024 was 21%.

b.Foreign income tax:
1.Income tax rates:

Presented hereunder are the income tax rates relevant to the Company’s Israeli subsidiary

2024 - 23%

2025 - 23%

2.As of December 31, 2025, the Company had U.S. federal net operating loss carryforwards of approximately $4,037 available to reduce future taxable income. There is a limitation on the amount of taxable income that can be offset by carryforwards after a change in control (generally greater than a 50% change in ownership). Losses from 2018 and forward that can only offset 80% of taxable income in a future year. The Company’s Israeli subsidiary has estimated total available carryforward operating tax losses for Israeli income tax purposes of approximately $4,955 as of December 31, 2025.
NOTE 9:-TAXES ON INCOME (Cont.)
c.Deferred income taxes:

Deferred income taxes reflect the net tax effects of temporary differences between the carrying amounts of assets and liabilities for financial reporting purposes and the amounts used for income tax purposes. Significant components of the Company’s deferred tax assets are as follows:

As of December 31,
2025 · 2024
Deferred tax assets:
Net operating loss carry forward$8,832$6,965
Deferred tax asset before valuation allowance1,9871,538
Valuation allowance(1,987)(1,538)
Net deferred tax asset$-$-
d.Reconciliation of the theoretical tax expense to the actual tax expense:

The main reconciling item between the statutory tax rate of the Company and the effective tax rate is the recognition of valuation allowance in respect of deferred taxes relating to accumulated net operating losses carried forward due to the uncertainty of the realization of such deferred taxes.

Year ended December 31,
2024 · 2023
Net loss, as reported in the consolidated statements of comprehensive loss$1,279$1,519
Statutory tax rate21%21%
Computed “expected” tax income269319
Valuation allowance(269)(319)
Taxes on income$-$-
NOTE 10:-SEGMENT REPORTING

ASC 280, “Segment Reporting,” establishes standards for reporting information about operating segments. Operating segments are defined as components of an enterprise about which separate financial information is available that is evaluated regularly by the chief operating decision maker (“CODM”) in deciding how to allocate resources and in assessing performance. The Company’s business is comprised ofone operating segment.

The Company’s CODM is its CEO, who reviews financial information presented on a consolidated basis.

The CODM uses consolidated net loss to assess financial performance and allocate resources. These financial metrics are used by the CODM to make key operating decisions, such as the allocation of budget between Research and development and General and Administrative expenses. Segment assets that are reviewed by the CODM are reported within the Consolidated Balance Sheet as consolidated total assets.

The table below summarizes the significant expense categories regularly reviewed by the CODM for the years ended December 31, 2025 and 2024:

20252024
Clinical developments$631776
Other segments expenses648743
$1,279$1,519
NOTE 11:-SELECTED STATEMENTS OF COMPREHENSIVE LOSS DATA
a.Research and development expenses:
20252024
Subcontractors and consultants$386$415
Share based payment245350
Laboratory services-11
$631$776
NOTE 11:-SELECTED STATEMENTS OF COMPREHENSIVE LOSS DATA (Cont.)
b.General and administrative expenses:
20252024
Professional services$366$483
Consulting services245244
Rent and office maintenance-3
Others33
$614$733
c.Financial expenses, net:
20252024
Bank fees$1$2
Interest on loan from related party17-
Exchange rate differences168
Total financial expenses, net$34$10

NOTE 12:- SUBSEQUENT EVENTS

In accordance with ASC 855-10, the Company’s management reviewed all material events through the date of this report and determined that there are no additional material subsequent events to report.

Exhibit NumberDescription
3.1Restated Certificate of Incorporation (incorporated by reference from Amendment No. 2 to our registration statement on Form 10 filed September 23, 2021).
3.2Bylaws (incorporated by reference from Amendment No. 2 to our registration statement on Form 10 filed September 23, 2021).
4.1Description of Securities (incorporated by reference from our Annual Report on Form 10-K filed March 30, 2022).
10.1Contractual Agreement between Raphael Pharmaceutical Ltd. and Way of Life Cannabis Ltd. (incorporated by reference from Amendment No. 2 to our registration statement on Form 10 filed September 23, 2021).
10.2Sponsored Research Agreement with Rambam Med-Tech Ltd. (incorporated by reference from Amendment No. 2 to our registration statement on Form 10 filed September 23, 2021).
10.3Supplement to Sponsored Research Agreement with Rambam Med-Tech Ltd. (incorporated by reference from our quarterly report on Form 10-Q filed November 14, 2022)
10.4English Translation of the Amendment to the Service Agreement by and between the Company and Yehuda Eliya, dated December 25, 2023 (incorporated by reference from our Annual Report on Form 10-K filed March 28, 2024).
10.5Management and Operations Agreement by and between the Company and Sheffa Enterprises, Inc., dated March 3, 2025 (incorporated by reference from our Annual Report on Form 10-K filed March 31, 2025).
10.6Operations Agreement by and between the Company and Model Engineering & Investments SRL and Guy Ofir, dated March 3, 2025 (incorporated by reference from our Annual Report on Form 10-K filed March 31, 2025).
10.7Service Agreement by and between the Company and Dr. Igal Louria Hayon, dated March 3, 2025 (incorporated by reference from our Annual Report on Form 10-K filed March 31, 2025).
10.8Service Agreement by and between the Company and Prof. Eliya Yehuda, dated March 10, 2025 (incorporated by reference from our Annual Report on Form 10-K filed March 31, 2025).
10.9Director and Chairman of the Board Service Agreement by and between the Company and Ajay Kumar Dhadha, dated March 5, 2025 (incorporated by reference from our Annual Report on Form 10-K filed March 31, 2025).
10.10*English Translation of the Amendment to the Service Agreement by and between the Company and Dr. Igal Louria Hayon, dated December 27, 2025.
10.11*English Translation of the Amendment to the Service Agreement by and between the Company and Guy Ofir, dated December 27, 2025.
10.12*English Translation of the Amendment to the Service Agreement by and between the Company and Shlomo Pilo, dated December 27, 2025.
10.13*English Translation of the Amendment to the Service Agreement by and between the Company and Ajay Kumar Dhadha, dated December 27, 2025.
10.14Amendment no. 1 to Sponsored Research Agreement by and between Rambam MedTech LTD and Raphael Pharmaceuticals Ltd., dated July 28, 2025 (incorporated by reference from our quarterly report on Form 10-Q filed August 13, 2025).
10.15Form of Subscription Agreement (incorporated by reference from our quarterly report on Form 10-Q filed May 15, 2025).
14.1Code of Business Conduct and Ethics (incorporated by reference from our Annual Report on Form 10-K filed March 31, 2025).
16.1Letter from Weinstein International CPA, addressed to the Securities and Exchange Commission, dated September 11, 2024 (incorporated by reference from our Current Report on Form 8-K filed September 11, 2024).
19.1Insider Trading Policy (incorporated by reference from our Annual Report on Form 10-K filed March 31, 2025).
21.1List of Subsidiaries of the Company (incorporated by reference from Amendment No. 2 to our registration statement on Form 10 filed September 23, 2021).
31.1*Certification of Chief Executive Officer pursuant to Sec. 302 of the Sarbanes-Oxley Act of 2002.
31.2*Certification of Chief Financial Officer pursuant to Sec. 302 of the Sarbanes-Oxley Act of 2002.
32.1**Certification of Chief Executive Officer pursuant to 18 U.S.C. Section 1350.
32.2**Certification of Chief Financial Officer pursuant to 18 U.S.C. Section 1350.
101*The following materials from the Company’s Annual Report on Form 10-K for the period ended December 31, 2025 formatted in XBRL (eXtensible Business Reporting Language): (i) the Consolidated Balance Sheets, (ii) the Consolidated Statements of Comprehensive Loss, (iii) the Statements of Changes in Stockholders’ Equity (Deficit), (iv) the Consolidated Statements of Cash Flows and (v) related notes to these financial statements, tagged as blocks of text and in detail.**
104*Cover Page Interactive Data File
*Filed herewith.
**Furnished herewith.
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