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Oruka Therapeutics, Inc.

For the period ended Sep 30, 2025. Filed Nov 12, 2025.

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About this filing

A company's report for each of its first three quarters. The financial statements are not audited. It shows how the business has moved since the last annual report, and what management says changed.

Sep 30, 2025 · Filed Nov 12, 2025

ORKA$104.56+1.7%Stored close · as of Nov 9, 2026

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Item 6. Exhibits

The exhibits filed or furnished as part of this Quarterly Report are set forth below.

EXHIBIT NUMBERDESCRIPTIONFORMEXHIBITFILING DATE
2.1†Agreement and Plan of Merger and Reorganization, dated as of April 3, 2024, by and among ARCA biopharma, Inc., Atlas Merger Sub Corp., Atlas Merger Sub II, LLC and Oruka Therapeutics, Inc.8-K2.1April 3, 2024
3.1Second Amended and Restated Certificate of Incorporation of the Company, filed September 3, 2024.8-K3.5September 5, 2024
3.2Amended and Restated Bylaws of the Company.8-K3.6September 5, 2024
3.3Form of Certificate of Designation of Preferences, Rights and Limitations of Series A Convertible Preferred Stock.S-1/A3.1(b)May 24, 2013
3.4Certificate of Elimination of Series A Convertible Preferred Stock, effective August 29, 2024.8-K3.8September 5, 2024
3.5Certificate of Designation of Preferences, Rights and Limitations of Series B Non-Voting Convertible Preferred Stock.8-K3.9September 5, 2024
3.6Certificate of Designation of Preferences, Rights and Limitations of Series A Non-Voting Convertible Preferred Stock.8-K3.1September 13, 2024
4.1Description of Securities.10-K4.1March 6, 2025
4.2Form of Pre-Funded Warrant, dated August 29, 2024.10-K4.3March 6, 2025
4.3Form of Pre-Funded Warrant, dated September 13, 2024.8-K4.1September 13, 2024
4.4Form of Pre-Funded Warrant, dated September 19, 2025.8-K4.1September 22, 2025
4.5Paruka Warrant, dated December 31, 202410-Q4.5May 14, 2025
10.1Securities Purchase Agreement, dated September 17, 2025, by and between Oruka Therapeutics, Inc. and each purchaser identified on Annex A thereto.8-K10.1September 22, 2025
10.2Form of Registration Rights Agreement, dated September 17, 2025.8-K10.2September 22, 2025
31.1*Certification of the Principal Executive Officer pursuant to Rule 13a-14(a) or 15d-14(a) promulgated under the Securities Exchange Act of 1934
31.2*Certification of the Principal Financial Officer pursuant to Rule 13a-14(a) or 15d-14(a) promulgated under the Securities Exchange Act of 1934
32.1**Certification of the Principal Executive Officer and Principal Financial Officer pursuant to 18 U.S.C. Section 1350 and Rule 13a-14(B) promulgated under the Securities Exchange Act of 1934
101.INSInline XBRL Instance Document
101.SCHInline XBRL Taxonomy Extension Schema with Embedded Linkbases Document
101.CALInline XBRL Taxonomy Extension Calculation Linkbase Document.
101.DEFInline XBRL Taxonomy Extension Definition Linkbase Document.
101.LABInline XBRL Taxonomy Extension Label Linkbase Document.
101.PREInline XBRL Taxonomy Extension Presentation Linkbase Document.
104Cover Page Interactive Data File (embedded within the Inline XBRL document)
*Filed herewith.
**Furnished herewith. The certifications on Exhibit 32.1 hereto are deemed not “filed” for purposes of Section 18 of the Exchange Act or otherwise subject to the liability of that Section. Such certifications will not be deemed incorporated by reference into any filing under the Securities Act or the Exchange Act.
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The text of this filing, as the company filed it with the SEC, without its images or exhibits. This is not investment advice.