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Summit Therapeutics Inc.

For the period ended Nov 4, 2026. Filed Oct 19, 2026.

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What shareholders are asked to vote on at a company's meeting. It is where to find what directors and top executives are paid, and who owns the most shares.

Nov 4, 2026 · Filed Oct 19, 2026

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SMMT$16.33+15.1%Stored close · as of Nov 6, 2026
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DEF 14A 1 d126889ddef14a.htm DEF 14A

UNITED STATES

SECURITIES AND EXCHANGE COMMISSION

WASHINGTON, D.C. 20549

SCHEDULE 14A

**(Rule 14a-101) **

Information Required in Proxy Statement

SCHEDULE 14A INFORMATION

Proxy Statement Pursuant to Section 14(a) of the

Securities Exchange Act of 1934

(Amendment No. )

Filed by the Registrant ☒

Filed by a Party other than the Registrant ☐

Check the appropriate box:

☐Preliminary Proxy Statement
☐Confidential, for Use of the Commission Only (as permitted by Rule 14a-6(e)(2))
☒Definitive Proxy Statement
☐Definitive Additional Materials
☐Soliciting Material Under Rule 14a-12

(Name of Registrant as Specified in its Charter)

(Name of Person(s) Filing Proxy Statement, if other than the Registrant)

Payment of Filing Fee (Check the appropriate box):

☒No fee required.
☐Fee paid previously with preliminary materials.
☐Fee computed on table in exhibit required by Item 25(b) per Exchange Act Rules 14a-6(i)(1) and 0-11.

601 Brickell Key Drive, Suite 1000

Miami, FL 33131

NOTICE OF SPECIAL MEETING OF STOCKHOLDERS

TO BE HELD AT 11:00 A.M. EASTERN TIME ON NOVEMBER 4, 2026

Dear Summit Therapeutics Inc. Stockholder:

You are cordially invited to attend a special meeting of stockholders (the “Special Meeting”) of Summit Therapeutics Inc. (the “Company,” “Summit,” “we,” “us” or “our”), which will be held on November 4, 2026 at 11:00 a.m. Eastern Time. The Special Meeting will be conducted virtually via live webcast. You will be able to vote and submit your questions during the meeting by visiting www.virtualshareholdermeeting.com/SMMT2026SM; to participate in the Special Meeting, you will need the control number included on your notice or proxy card. Please have your notice or proxy card in hand when you visit the website. During the Special Meeting, stockholders will be asked to vote on the following proposals, as more fully described in the accompanying proxy statement (“Proxy Statement”):

1.To approve an amendment to the Company’s Restated Certificate of Incorporation to increase the number of authorized shares of common stock by 1,000,000,000 (from 1,000,000,000 to 2,000,000,000).
2.To transact such other business as may properly come before the Special Meeting or any adjournments or postponements thereof.

Our Board of Directors has fixed the close of business on October 1, 2026 as the record date for the Special Meeting. Only stockholders of record on October 1, 2026 are entitled to notice of and to vote at the Special Meeting. This Proxy Statement is being mailed to stockholders on or about October 19, 2026. It is important that your shares are represented and voted at the Special Meeting. For specific voting instructions, please refer to the information provided in the Proxy Statement, together with your proxy card or the voting instructions you received with the Proxy Statement.

If you intend to vote via the Internet, telephone or mail, your vote must be received by 11:59 p.m. Eastern Time, on November 3, 2026. For specific voting instructions, please refer to the information provided in the Proxy Statement, together with your proxy card or the voting instructions you received with the Proxy Statement.

YOUR VOTE IS IMPORTANT. Whether or not you plan to attend the virtual Special Meeting, we request that you submit your vote via the Internet, telephone or mail.

Thank you for your continued support of Summit Therapeutics Inc.

By Order of the Board of Directors,

/s/ Robert W. Duggan

Robert W. Duggan

Co-Chief Executive Officer and Chairman of the Board of Directors

Miami, FL

October 19, 2026

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