Septerna, Inc.

For the period ended Jun 30, 2026. Filed Aug 10, 2026.

About this filing

A company's report for each of its first three quarters. The financial statements are not audited. It shows how the business has moved since the last annual report, and what management says changed.

Jun 30, 2026 · Filed Aug 10, 2026

SEPN$52.34+3.2%Stored close · as of Nov 10, 2026

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Condensed Statements of Operations and Comprehensive Loss

(In thousands, except for share and per share data)

	Three Months Ended June 30,		Six Months Ended June 30,
	2026	2025	2026	2025
Revenue	$26,746	$119	$53,269	$338
Operating expenses:
Research and development	35,132	22,188	64,667	41,459
General and administrative	8,450	6,909	18,738	13,767
Total operating expenses	43,582	29,097	83,405	55,226
Loss from operations	(16,836)	(28,978)	(30,136)	(54,888)
Other income, net:
Interest income	4,798	4,165	9,829	8,627
Other expense, net	(23)	(25)	(54)	(53)
Total other income, net	4,775	4,140	9,775	8,574
Loss before provision for income taxes	(12,061)	(24,838)	(20,361)	(46,314)
Provision for income taxes	(973)	—	(1,310)	—
Net loss	$(13,034)	$(24,838)	$(21,671)	$(46,314)
Net loss per share, basic and diluted	$(0.29)	$(0.56)	$(0.48)	$(1.05)
Weighted-average shares outstanding, basic and diluted	45,040,075	44,165,168	44,896,601	44,051,918
Comprehensive loss:
Net loss	$(13,034)	$(24,838)	$(21,671)	$(46,314)
Net unrealized (loss) gain on marketable securities	(693)	(22)	(1,879)	120
Total other comprehensive (loss) income	(693)	(22)	(1,879)	120
Comprehensive loss	$(13,727)	$(24,860)	$(23,550)	$(46,194)

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