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Tempest Therapeutics, Inc.

For the period ended Dec 31, 2025. Filed Mar 30, 2026.

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A company's yearly report to the SEC, with audited financial statements. It is the fullest account a company gives of its business, its finances and the risks it sees.

FY2025 · Filed Mar 30, 2026

TPST$0.37+3.5%Stored close · as of Nov 10, 2026

Extracted filing text, with the paragraph anchors used by the comparison.

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Contents

Item 15. Exhibit and Financial Statement Schedules

ITEM 15. EXHIBITS AND FINANCIAL STATEMENT SCHEDULES

We have filed the following documents as part of this Annual Report:

(a)(1) Financial Statements

The financial statements are included in Item 8. “Financial Statements and Supplementary Data.”

(a)(2) Financial Statement Schedules

All schedules are omitted as information required is inapplicable or the information is presented in the financial statements and the related notes.

(a)(3) Exhibits

Incorporation by Reference
Exhibit NumberDescription of ExhibitFormFile NumberExhibitFiling DateFiled or Furnished Herewith
2.1*Agreement and Plan of Merger, dated as of March 29, 2021, by and among Tempest Therapeutics, Inc., Mars Merger Corp. and Tempest Therapeutics, Inc.8-K001-358902.13/29/2021
3.1Restated Certificate of Incorporation of the Registrant, as amended10-Q001-358903.15/15/2019
3.2Certificate of Amendment to the Restated Certificate of Incorporation of the Company, as filed with the Secretary of State of the State of Delaware on June 24, 20218-K001-358903.16/28/2021
3.3Certificate of Amendment to the Restated Certificate of Incorporation of the Company, as filed with the Secretary of State of the State of Delaware on June 25, 20218-K001-358903.26/28/2021
3.4Certificate of Designation of Series A Junior Participating Preferred Stock filed with the Secretary of State of the State of Delaware on October 10, 20238-K001-358903.110/11/2023
3.5Certificate of Amendment to the Restated Certificate of Incorporation of the Company, as filed with the Secretary of State of the State of Delaware on April 4, 2025.8-K001-358903.14/7/2025
3.6Amended and Restated Bylaws of the Registrant8-K001-358903.19/24/2021
4.1Description of Securities Registered Pursuant to Section 12 of the Securities Exchange Act of 1934X
4.2Form of Tempest Therapeutics, Inc. Warrant to Purchase Stock10-K001-358904.13/19/2024
4.3Rights Agreement, dated as of October 10, 2023, between Tempest Therapeutics, Inc. and Computershare Trust Company, N.A., which includes the form of Certificate of Designation as Exhibit A, the form of Right Certificate as Exhibit B and the Summary of Rights to Purchase Preferred Shares as Exhibit C8-K001-358904.110/11/2023
4.4Amendment No. 1, dated as of October 9, 2024, to Rights Agreement, dated as of October 10, 2023, by and between Tempest Therapeutics, Inc. and Computershare Trust Company, N.A., as rights agent8-K001-358904.110/10/2024
4.5Amendment No. 2, dated as of December 5, 2024, to Rights Agreement, dated as of October 10, 2023, as amended, by and between Tempest Therapeutics, Inc. and Computershare Trust Company, N.A., as rights agent.8-K001-358904.112/06/2024
4.6Form of Tempest Therapeutics, Inc. Prefunded Warrant8-K001-358904.211/26/2025
4.7Form of Tempest Therapeutics, Inc. Common Stock Warrant8-K001-358904.311/26/2025
4.8Warrant Agreement (including Form of Warrant), dated February 3, 2026, between the Company, Computershare Inc., a Delaware corporation, and Computershare Trust Company, N.A., as Warrant Agent8-K001-358904.12/6/2026
10.1+2011 Equity Incentive PlanS-8333-25772710.27/7/2021
10.2+2017 Equity Incentive PlanS-8333-25772710.17/7/2021
10.3+Form of Stock Option Agreement under the 2017 Equity Incentive Plan10-K001-3589010.33/29/2022
10.4+Amended and Restated 2019 Equity Incentive Plan8-K001-3589010.16/21/2022
10.5+Form of Option Grant Package under 2019 Equity Incentive Plan10-Q001-3589010.78/12/2019
10.6+Form of Stock Option Agreement under the Sub Plan for French Residents under 2019 Equity Incentive Plan10-K001-3589010.163/11/2020
10.7+Form of Inducement Nonqualified Stock Option Agreement subject to the terms of the 2019 Equity Incentive Plan10-K001-3589010.173/11/2020
10.8+Amended and Restated 2019 Employee Stock Purchase Plan8-K001-3589010.26/21/2022
10.9+Form of Indemnification Agreement8-K001-3589010.17/07/2021
10.10Lease Agreement, dated January 24, 2022, by and between HCP Life Science REIT, Inc. and Tempest Therapeutics, Inc.10-K001-3589010.2403/22/2023
10.11+Tempest Therapeutics, Inc. Amended and Restated 2023 Equity Incentive Plan10-Q001-3589010.18/10/2023
10.12+Amendment No. 1 to Tempest Therapeutics, Inc. Amended and Restated 2023 Equity Incentive PlanX
10.13+Form of Option Grant Package under the Amended and Restated 2023 Equity Incentive Plan10-Q001-3589010.28/10/2023
10.14+Tempest Therapeutics, Inc. 2023 Inducement Plan10-Q001-3589010.38/10/2023
10.15+Form of Option Grant Package under the 2023 Inducement Plan10-Q001-3589010.48/10/2023
10.16#Roche Supply Agreement, dated October 7, 2024, by and between the Registrant and F. Hoffmann-La Roche Ltd.10-K001-3589010.323/27/2025
10.17+Amended and Restated Offer Letter, dated August 11, 2025, by and between Tempest Therapeutics, Inc. and Justin Trojanowski.10-Q001-3589010.78/11/2025
10.18+Separation Agreement, dated June 13, 2025, by and between Tempest Therapeutics, Inc. and Stephen Brady10-Q001-3589010.38/11/2025
10.19+Separation Agreement, dated June 13, 2025, by and between Tempest Therapeutics, Inc. and Samuel Whiting10-Q001-3589010.48/11/2025
10.20+Separation Agreement, dated June 13, 2025, by and between Tempest Therapeutics, Inc. and Nicholas Maestas10-Q001-3589010.58/11/2025
10.21+Form of Consulting Agreement10-Q001-3589010.28/11/2025
10.22+Form of Success Bonus Agreement10-Q001-3589010.68/11/2025
10.23*Asset Purchase Agreement, dated November 19, 2025, by and among Erigen LLC, Factor Bioscience Inc., and Tempest Therapeutics, Inc.8-K001-3589010.111/19/2025
10.24Lock-Up Agreement, dated November 19, 2025, by and between Erigen LLC and Tempest Therapeutics, Inc.8-K001-3589010.211/19/2025
10.25#Exclusive License and Collaboration Agreement, dated July 18, 2025, by and between Erigen LLC and Novatim Immune Therapeutics Co., Ltd.X
10.26#Amended and Restated License and Collaboration Agreement, dated November 19, 2025, by and between Factor Bioscience Limited and Erigen LLCX
10.27#Amended and Restated Master Services Agreement, dated November 19, 2025, by and between Factor Bioscience Limited and Erigen LLCX
10.28+Executive Employment Agreement, dated November 19, 2025, by and between the Registrant and Matthew AngelX
10.29+Executive Employment Agreement, dated February 3, 2026 by and between the Registrant and Nicholas MaestasX
19.1Tempest Therapeutics, Inc. Insider Trading Policy10-K001-3589019.13/27/25
21.1Subsidiaries of the Registrant10-K/A001-3589021.14/1/2022
23.1Consent of Ernst & Young LLP, independent registered public accounting firmX
24.1Power of Attorney (included on signature page)X
31.1Certification of Principal Executive Officer pursuant to Rules 13a-14(a) and 15d-14(a) promulgated under the Securities Exchange Act of 1934, as adopted pursuant to Section 302 of the Sarbanes-Oxley Act of 2002X
31.2Certification of Principal Financial Officer pursuant to Rules 13a-14(a) and 15d-14(a) promulgated under the Securities Exchange Act of 1934, as adopted pursuant to section 302 of the Sarbanes-Oxley Act of 2002X
32.1^Certification of Principal Executive Officer and Principal Financial Officer pursuant to Rules 13a-14(b) and 15d-14(b) promulgated under the Securities Exchange Act of 1934 and 18 U.S.C. Section 1350, as adopted pursuant to section 906 of The Sarbanes-Oxley Act of 2002X
97.1+Incentive Compensation Recoupment Policy10-K001-3589097.103/19/2024
101.INSInline XBRL Instance Document – the instance document does not appear in the Interactive Data File as its XBRL tags are embedded within the Inline XBRL documentX
101.SCHInline XBRL Taxonomy Extension Schema With Embedded Linkbase DocumentX
104Cover Page formatted as Inline XBRL and contained in Exhibit 101
  • Exhibits and/or schedules have been omitted pursuant to Item 601(a)(5) of Regulation S-K. The registrant hereby undertakes to furnish supplementally copies of any of the omitted exhibits and schedules upon request by the SEC.
  • Indicates management contract or compensatory plan.

^ These certifications are being furnished solely to accompany this Annual Report pursuant to 18 U.S.C. Section 1350, and are not being filed for purposes of Section 18 of the Securities Exchange Act of 1934, as amended, and are not to be incorporated by reference into any filing of the Registrant, whether made before or after the date hereof, regardless of any general incorporation language in such filing.

Pursuant to Item 601(b)(10)(iv) of Regulation S-K, certain portions of this exhibit (indicated by ***) have been omitted because the identified information is not material and is the type that the Registrant treats as private or confidential.

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