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Pyxis Oncology, Inc.

For the period ended Dec 31, 2025. Filed Mar 23, 2026.

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A company's yearly report to the SEC, with audited financial statements. It is the fullest account a company gives of its business, its finances and the risks it sees.

FY2025 · Filed Mar 23, 2026

PYXS$1.70+2.4%Stored close · as of Nov 9, 2026

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Contents

Item 9B. Other Information

Trading arrangement

During the quarter ended December 31, 2025, none of our directors or officers (as defined in Rule 16a-1(f) under the Exchange Act)adoptedor terminatedany “Rule 10b5-1 trading arrangement” or “non-Rule 10b5-1 trading arrangement,” as each term is defined in Item 408 of Regulation S-K for the purchase or sale of our securities, except as set forth below:

Name and TitleType of PlanAdoption or Termination DatePlan Start DatePlan End DateAggregate Number of Securities to be SoldDescription of Trading Arrangement
Lara Sullivan, M.D., Former President, Chief Executive Officer and Chief Medical Officer and Current DirectorRule 10b5-1 trading arrangementAdopted on December 22, 2025December 22, 2025March 31, 2027411,845Sales of shares intended to satisfy the affirmative defense of Rule 10b5–1(c)
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The text of this filing, as the company filed it with the SEC, without its images or exhibits. This is not investment advice.