Artiva Biotherapeutics, Inc.

Risk Management and Strategy

Our cybersecurity risk management and strategy program consist of cybersecurity-related policies and procedures, industry standard technology solutions including antivirus, firewalls and monitoring tools, awareness training for employees, periodic testing, cybersecurity insurance coverage and an incident response plan. We have implemented and maintain various information security processes designed to identify, assess, and manage material risks from cybersecurity threats to our critical computer networks, third party hosted services, communications systems, hardware and software, and our critical data, including intellectual property and confidential information that is proprietary, strategic or competitive in nature (Information Systems and Data).

Our information security and legal functions help identify, assess and manage the Company’s cybersecurity threats and risks, as well as identify and assess risks from cybersecurity threats by monitoring and evaluating our threat environment using various methods including, for example using certain manual and automated tools, analyzing reports of threats and actors, conducting scans of the threat environment, evaluating our industry’s risk profile, evaluating threats reported to us, conducting internal and external audits, conducting threat assessments for both internal and external threats, and conducting third-party led tabletop incident response exercises.

Depending on the environment, we implement and maintain various technical, physical, and organizational measures, processes, standards and policies designed to manage and mitigate material risks from cybersecurity threats to our Information Systems and Data, including, for example maintaining an incident response plan and policies, maintaining disaster recovery and business continuity plans, conducting risk assessments, implementing certain security standards, encrypting certain data, maintaining network security controls, segregating certain data, maintaining access controls, monitoring systems, implementing a vendor risk management program, conducting periodic employee training, penetration testing, maintaining cybersecurity insurance, asset management tracking and disposal, physical security measures, and physical security controls.

Our assessment and management of material risks from cybersecurity threats areintegrated into the Company’s overall risk management processes. For example, (1) Cybersecurity risk is addressed as a component of the Company’s enterprise risk management program;(2) The security administrator works with management to prioritize our risk management processes and mitigate cybersecurity threats that are more likely to lead to a material impact on our business; (3) Our management evaluates material risks from cybersecurity threats against our overall business objectives and reports to the audit committee of the board of directors, which evaluates our overall enterprise risk; and (4) We have a cybersecurity incident response plan to identify, assess, respond to, and inform escalating levels of management based on the nature and severity of such incidents.

Weuse third-party service providers to assist us from time to time toidentify, assess, and manage material risks from cybersecurity threats, including for example cybersecurity software providers and penetration testing firms. We also use third-party service providers to perform a variety of functions throughout our business, such as contract research organizations, application providers, distributors, and supply chain resources. We assess and manage cybersecurity risks associated with our use of these providers by conducting risk assessments for certain vendors, obtaining third party reporting relating to reputation and litigation screening for these vendors, requiring security questionnaires, and reviewing relevant security assessments.

For a description of the risks from cybersecurity threats thatmay materially affect the Company and how they may do so, see the section titled “Risk Factors” in Part I. Item 1A of this Annual Report on Form 10-K, including the risk factor titled “—Our internal computer systems, or those used by our CROs or other contractors or consultants, may fail or experience security breaches or other unauthorized or improper access.”

Governance

The audit committee of our board of directors is responsible for oversight the Company’s cybersecurity risk, including oversight and mitigation of risks from cybersecurity threats.

Our cybersecurity risk assessment and management processes are implemented and maintained by certain Company management, including our information security and legal functions. Ourhead of information technologyis responsible for integrating cybersecurity risk considerations into the Company’s overall risk management strategy, communicating key priorities to relevant personnel, approving budgets, helping prepare for cybersecurity incidents, approving cybersecurity processes, reviewing security assessments and other security-related reports, and retaining assessors, consultants, auditors, or third parties in connection with the company’s cybersecurity program. We design and assess our program based on the National Institute of Standards and Technology Cybersecurity Framework (NIST CSF) in an effort to help us identify, assess, and manage cybersecurity risks relevant to our business. It does not, however, mean that we meet any particular technical standards, specifications, or requirements.

Our cybersecurity incident response policy and plans are designed to escalate certain cybersecurity incidents to members of management depending on the circumstances. The Senior Director of Information Technology (IT)has over 25 years of relevant experience and works with the Company’s incident response team, which consists of members of IT, legal, compliance, human resources, and others as applicable, to help the Company mitigate and remediate cybersecurity incidents of which they are notified. In addition, the Company’s incident response policy and plans include reporting to the audit committee of the board of directors for certain cybersecurity incidents.

The audit committee receives periodic reports from management concerning the Company’s significant cybersecurity threats and risk and the processes the Company has implemented to address them. The audit committee also has access to various reports, summaries or presentations related to cybersecurity threats, risk and mitigation.