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SPRUCE BIOSCIENCES, INC.

For the period ended Dec 31, 2025. Filed Mar 9, 2026.

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About this filing

A company's yearly report to the SEC, with audited financial statements. It is the fullest account a company gives of its business, its finances and the risks it sees.

FY2025 · Filed Mar 9, 2026

SPRB$49.34+6.0%Stored close · as of Nov 9, 2026

Extracted filing text, with the paragraph anchors used by the comparison.

See the whole filing, with its images and exhibits
Contents

Table of Contents

Page
SPECIAL NOTE REGARDING FORWARD-LOOKING STATEMENTS1
SUMMARY OF RISKS ASSOCIATED WITH OUR BUSINESS2
PART I
Item 1.Business4
Item 1A.Risk Factors28
Item 1B.Unresolved Staff Comments86
Item 1C.Cybersecurity86
Item 2.Properties87
Item 3.Legal Proceedings87
Item 4.Mine Safety Disclosures87
PART II
Item 5.Market for Registrant’s Common Equity, Related Stockholder Matters and Issuer Purchases of Equity Securities88
Item 6.[Reserved]88
Item 7.Management’s Discussion and Analysis of Financial Condition and Results of Operations89
Item 7A.Quantitative and Qualitative Disclosures About Market Risk98
Item 8.Financial Statements and Supplementary Data99
Item 9.Changes in and Disagreements With Accountants on Accounting and Financial Disclosure127
Item 9A.Controls and Procedures127
Item 9B.Other Information128
Item 9C.Disclosure Regarding Foreign Jurisdictions that Prevent Inspections128
PART III
Item 10.Directors, Executive Officers and Corporate Governance129
Item 11.Executive Compensation129
Item 12.Security Ownership of Certain Beneficial Owners and Management and Related Stockholder Matters129
Item 13.Certain Relationships and Related Transactions, and Director Independence129
Item 14.Principal Accountant Fees and Services130
PART IV
Item 15.Exhibit and Financial Statement Schedules131

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ContentsView on SEC.gov

The text of this filing, as the company filed it with the SEC, without its images or exhibits. This is not investment advice.