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REGENXBIO Inc.

For the period ended Dec 31, 2025. Filed Mar 5, 2026.

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About this filing

A company's yearly report to the SEC, with audited financial statements. It is the fullest account a company gives of its business, its finances and the risks it sees.

FY2025 · Filed Mar 5, 2026

RGNX$8.07+5.9%Stored close · as of Nov 9, 2026

Extracted filing text, with the paragraph anchors used by the comparison.

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Contents

Exhibit Index

Incorporated by Reference
ExhibitNumberDescriptionFormExhibitNumberFiling DateFiled orFurnishedHerewith
1.1Sales Agreement dated December 9, 2024 between the Registrant and Leerink Partners LLC8-K1.112/9/24
3.1Restated Certificate of Incorporation8-K3.16/7/21
3.2Amended and Restated BylawsX
4.1Specimen stock certificate evidencing the shares of common stockS-14.18/17/15
4.2Description of Securities10-K4.23/13/25
4.3Form of Pre-funded Warrant8-K4.13/11/24
4.4REGENXBIO Inc. Warrant to Purchase Common StockS-34.56/13/25
10.1Form of Indemnity Agreement for directors and officersS-110.18/17/15
10.2*2015 Equity Incentive PlanS-1/A10.39/15/15
10.3*Form of Restricted Stock Unit Award Agreement for the 2015 Equity Incentive Plan10-K10.43/1/21
10.4*Form of Stock Option Award Agreement for the 2015 Equity Incentive Plan10-K10.53/1/21
10.5*REGENXBIO Inc. 2025 Equity Incentive PlanS-899.16/13/25
10.6*Form of Restricted Stock Unit Award Agreement for the 2025 Equity Incentive Plan10-Q10.28/7/25
10.7*Form of Stock Option Award Agreement for the 2025 Equity Incentive Plan10-Q10.38/7/25
10.8*2015 Employee Stock Purchase PlanS-1/A10.49/8/15
10.9*Employment Agreement effective as of July 1, 2024 between the Registrant and Curran Simpson10-Q10.18/1/24
10.10*Form of Employment Agreement for Executive Vice Presidents10-K10.92/27/24
10.11*Compensation Program for Non-Employee Directors10-Q10.18/3/22
10.12*Management Cash Incentive PlanS-110.298/17/15
10.13†License Agreement effective February 24, 2009 between the Registrant and The Trustees of the University of PennsylvaniaS-1/A10.99/15/15
10.14†First Amendment to License Agreement dated March 6, 2009 between the Registrant and The Trustees of the University of PennsylvaniaS-110.108/17/15
10.15†Second Amendment to License Agreement effective September 9, 2014 between the Registrant and The Trustees of the University of PennsylvaniaS-1/A10.119/15/15
10.16†Third Amendment to License Agreement effective April 29, 2016 between the Registrant and The Trustees of the University of Pennsylvania10-Q/A10.3612/23/16
10.17†Fourth Amendment to License Agreement effective April 4, 2019 between the Registrant and The Trustees of the University of Pennsylvania10-Q10.25/7/19
Incorporated by Reference
ExhibitNumber · Description · Form · ExhibitNumber · Filing Date · Filed orFurnishedHerewith
10.18†Fifth Amendment to License Agreement effective September 11, 2020 between the Registrant and The Trustees of the University of Pennsylvania10-Q10.211/4/20
10.19†Letter Agreement dated March 21, 2022 between the Company and the Trustees of the University of Pennsylvania10-Q10.15/4/22
10.20†License Agreement dated March 6, 2009 between the Registrant and SmithKline Beecham Corporation d/b/a GlaxoSmithKlineS-1/A10.129/15/15
10.21Amendment to License Agreement dated April 15, 2009 between the Registrant and SmithKline Beecham Corporation d/b/a GlaxoSmithKlineS-110.138/17/15
10.22†License Agreement dated March 21, 2014 between the Registrant and AveXis, Inc.S-1/A10.169/15/15
10.23†First Amendment to License Agreement dated January 8, 2018 between the Registrant and AveXis, Inc.10-K10.243/6/18
10.24†Collaboration and License Agreement dated September 10, 2021 between the Registrant and AbbVie Global Enterprises Ltd.10-Q10.111/2/21
10.25†First Amendment to Collaboration and License Agreement dated August 5, 2025 between the Registrant and AbbVie Global Enterprises Ltd.10-Q10.111/6/25
10.26†Collaboration and License Agreement dated January 14, 2025 between the Registrant and Nippon Shinyaku Co., Ltd.10-Q10.15/12/25
10.27Lease dated March 6, 2015 between the Registrant and BMR-Medical Center Drive LLCS-110.268/17/15
10.28First Amendment to Lease dated September 30, 2015 between the Registrant and BMR-Medical Center Drive LLC10-K10.313/3/16
10.29Second Amendment to Lease dated November 23, 2015 between the Registrant and BMR-Medical Center Drive LLC10-K10.323/3/16
10.30Third Amendment to Lease dated July 21, 2017 between the Registrant and BMR-Medical Center Drive LLC10-Q10.18/8/17
10.31Fourth Amendment to Lease dated April 20, 2018 between the Registrant and BMR-Medical Center Drive LLC10-Q10.15/8/18
10.32Fifth Amendment to Lease dated October 30, 2020 between the Registrant and ARE-Maryland No. 45, LLC, as successor in interest to BMR-Medical Center Drive LLC10-Q10.311/4/20
10.33Lease dated November 1, 2018 between the Registrant and ARE-Maryland No. 24, LLC10-Q10.111/7/18
10.34Letter Agreement to Lease dated April 12, 2019 between the Registrant and ARE-Maryland No. 24, LLC10-Q10.35/7/19
10.35First Amendment to Lease dated April 23, 2019 between the Registrant and ARE-Maryland No. 24, LLC10-Q10.45/7/19
Incorporated by Reference
ExhibitNumberDescriptionFormExhibitNumberFiling DateFiled orFurnishedHerewith
10.36Second Amendment to Lease dated November 4, 2019 between the Registrant and ARE-Maryland No. 24, LLC10-Q10.111/5/19
10.37Third Amendment to Lease dated October 30, 2020 between the Registrant and ARE-Maryland No. 24, LLC10-Q10.411/4/20
10.38†Royalty Purchase Agreement dated December 22, 2020 between the Registrant and entities managed by Healthcare Royalty Management, LLC10-K10.423/1/21
10.39†Loan Agreement dated May 16, 2025 between REGENXBIO RS LLC and affiliate of Healthcare Royalty Management, LLC10-Q10.48/7/25
19.1Insider Trading Policy10-K19.13/13/25
21.1Subsidiaries of the RegistrantX
23.1Consent of PricewaterhouseCoopers LLP, independent registered accounting firmX
31.1Certification of the Chief Executive Officer, as required by Section 302 of the Sarbanes-Oxley Act of 2002X
31.2Certification of the Chief Financial Officer as required by Section 302 of the Sarbanes-Oxley Act of 2002X
32.1Certifications of the Chief Executive Officer and Chief Financial Officer as required by 18 U.S.C. 1350X
97.1Compensation Clawback Policy10-K97.12/27/24
101The following materials from the Registrant’s Annual Report on Form 10-K for the fiscal year ended December 31, 2025 formatted in Inline XBRL (eXtensible Business Reporting Language): (i) Consolidated Balance Sheets(ii) Consolidated Statements of Operations and Comprehensive Loss(iii) Consolidated Statements of Stockholders’ Equity(iv) Consolidated Statements of Cash Flows(v) Notes to Consolidated Financial StatementsX
104The cover page from the Registrant’s Annual Report on Form 10-K for the fiscal year ended December 31, 2025 formatted in Inline XBRL (included in Exhibit 101)
  • Management contract or compensatory plan or arrangement.

† Portions of this exhibit have been omitted.

The certifications attached as Exhibit 32.1 that accompany this Annual Report on Form 10-K are not deemed filed with the SEC and are not to be incorporated by reference into any filing of REGENXBIO Inc. under the Securities Act or the Exchange Act, whether made before or after the date of this Annual Report on Form 10-K, irrespective of any general incorporation language contained in such filing.

ContentsView on SEC.gov

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