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Sarepta Therapeutics, Inc.

For the period ended Dec 31, 2025. Filed Mar 2, 2026.

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A company's yearly report to the SEC, with audited financial statements. It is the fullest account a company gives of its business, its finances and the risks it sees.

FY2025 · Filed Mar 2, 2026

SRPT$16.42-4.8%Stored close · as of Nov 10, 2026

Extracted filing text, with the paragraph anchors used by the comparison.

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Contents

Item 15. Exhibits, Financial Statement Schedules

(a) The following documents are filed as part of this Annual Report on Form 10-K:

(1) Financial Statements

The following consolidated financial statements of the Company and the Report of KPMG LLP, Independent Registered Public Accounting Firm, are included in Part IV of this Annual Report on Form 10-K on the pages indicated:

Report of Independent Registered Public Accounting Firm (KPMG LLP, Boston, MA, Auditor Firm ID: 185)F-2
Consolidated Balance SheetsF-4
Consolidated Statements of Comprehensive (Loss) IncomeF-5
Consolidated Statements of Stockholders’ EquityF-6
Consolidated Statements of Cash FlowsF-7
Notes to Consolidated Financial StatementsF-8

(2) Financial Statement Schedules

All schedules are omitted because they are not applicable or the required information is shown in the consolidated financial statements or the notes thereto.

(3) Exhibits

The exhibits required by Item 601 of Regulation S-K are listed in paragraph (b) below.

(b) Exhibits.

The following exhibits are filed herewith or are incorporated by reference to exhibits filed with the SEC:

Incorporated by Reference to Filings Indicated
ExhibitNumber · Description · Form · File No. · Exhibit · FilingDate · ProvidedHerewith
2.1Agreement and Plan of Merger dated June 6, 2013 between Sarepta Therapeutics, Inc., a Delaware corporation, and Sarepta Therapeutics, Inc., an Oregon corporation.8-K12B001-148952.16/6/13
2.2*Warrant to Purchase Common Stock of Myonexus Therapeutics, Inc., issued by Myonexus Therapeutics, Inc. to Sarepta Therapeutics, Inc., dated as of May 3, 2018.10-Q001-148952.18/8/18
3.1Amended and Restated Certificate of Incorporation.8-K12B001-148953.16/6/13
3.2Amendment to the Amended and Restated Certificate of Incorporation.8-K001-148953.16/30/15
3.3Second Amended and Restated ByLaws of Sarepta Therapeutics, Inc.8-K001-148953.112/13/22
3.4Amendment No. 1 to Second Amended and Restated Bylaws of Sarepta Therapeutics, Inc.8-K001-148953.19/16/24
4.1Form of Specimen Certificate for Common Stock.10-Q001-148954.18/8/13
4.2Indenture, dated as of September 16, 2022, by and between Sarepta Therapeutics, Inc. and U. S. Bank Trust Company, National Association (including the form of the 1.250% Convertible Senior Note due 2027).8-K001-148954.19/19/22

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4.3Form of 2027 Note (included in Exhibit 4.2)8-K001-148954.29/19/22
4.4Indenture, dated as of August 28, 2025, by and between Sarepta Therapeutics, Inc. and U.S. Bank Trust Company, National Association (including the form of the 4.875% Convertible Senior Note due2030).8-K001-148954.18/29/25
4.5First Supplemental Indenture, dated as of December 18, 2025, by and between Sarepta Therapeutics, Inc. and U.S. Bank Trust Company, National Association.8-K001-148954.112/19/25
4.6Form of 2030 Note (included in Exhibit 4.4)8-K001-148954.18/29/25
4.7Description of Registered Securities10-K001-148954.42/26/20
10.1†Sarepta Therapeutics, Inc. Amended and Restated 2011 Equity Incentive Plan.8-K001-1489510.17/1/16
10.2†Form of Stock Option Award Agreement under the Amended and Restated 2011 Equity Incentive Plan.10-K001-1489510.132/28/17
10.3†Form of Restricted Stock Agreement under the Amended and Restated 2011 Equity Incentive Plan.10-K001-1489510.142/28/17
10.4†Form of Restricted Stock Unit Award Agreement under 2011 Equity Incentive Plan.10-K001-1489510.172/28/17
10.5†Form of Stock Appreciation Right Award Agreement under the 2011 Equity Incentive Plan.10-K001-1489510.182/28/17
10.6†Sarepta Therapeutics, Inc. Amended and Restated 2013 Employee Stock Purchase Plan.8-K001-1489510.27/1/16
10.7†Sarepta Therapeutics, Inc. 2014 Employment Commencement Incentive Plan, as amended.S-8001-148954.42/25/16
10.8†Form of Stock Option Award Agreement under 2014 Employment Commencement Incentive Plan10-K001-1489510.283/3/14
10.9*Amended and Restated Exclusive License Agreement by and among The University of Western Australia, Sarepta Therapeutics, Inc., and Sarepta International CV dated April 10, 2013.10-Q001-1489510.15/9/13
10.10*First Amendment to License Agreement by and among The University of Western Australia, Sarepta Therapeutics, Inc., and Sarepta International CV dated June 19, 2016.10-Q001-1489510.18/9/16
10.11†Amendment No. 1 to the Sarepta Therapeutics, Inc. Amended and Restated 2011 Equity Incentive Plan8-K001-1489510.16/30/15
10.12Asset Purchase Agreement dated February 20, 2017 by and between Sarepta Therapeutics Inc. and Gilead Sciences, Inc.10-Q001-1489510.15/4/17
10.13†Employment Agreement, dated as of June 26, 2017, between Sarepta Therapeutics, Inc. and Douglas S. Ingram8-K001-1489510.16/28/17
10.14†Change in Control and Severance Agreement by and between Douglas S. Ingram and Sarepta Therapeutics, Inc., effective June 26, 20178-K001-1489510.26/28/17
10.15†Amendment No. 1 to the Sarepta Therapeutics, Inc. 2014 Employment Commencement Incentive Plan8-K001-1489510.36/28/17
10.16†Restricted Stock Agreement under the 2014 Employment Commencement Incentive Plan8-K001-1489510.46/28/17

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10.17†Performance Stock Option Award Agreement under the 2014 Employment Commencement Incentive Plan8-K001-1489510.56/28/17
10.18*Settlement Agreement between Sarepta Therapeutics, Inc., Sarepta International C.V. and The University of Western Australia on the one hand, and BioMarin Leiden Holding BV, BioMarin Nederlands BV and BioMarin Technologies BV on the other hand dated July 17, 201710-Q001-1489510.78/3/17
10.19*License Agreement between Sarepta Therapeutics, Inc. and Sarepta International C.V. on the one hand and BioMarin Leiden Holding BV, BioMarin Nederlands BV and BioMarin Technologies BV on the other hand dated July 17, 201710-Q001-1489510.88/3/17
10.20Base Call Option Transaction Confirmation, dated as of September 13, 2022, between Sarepta Therapeutics, Inc. and Barclays Bank PLC.8-K001-1489510.39/19/22
10.21Base Call Option Transaction Confirmation, dated as of September 13, 2022, between Sarepta Therapeutics, Inc. and Goldman Sachs & Co. LLC.8-K001-1489510.49/19/22
10.22Base Call Option Transaction Confirmation, dated as of September 13, 2022, between Sarepta Therapeutics, Inc. and Mizuho Markets Americas LLC.8-K001-1489510.59/19/22
10.23Base Call Option Transaction Confirmation, dated as of September 13, 2022, between Sarepta Therapeutics, Inc. and Morgan Stanley & Co. LLC.8-K001-1489510.69/19/22
10.24Base Call Option Transaction Confirmation, dated as of September 13, 2022, between Sarepta Therapeutics, Inc. and RBC Capital Markets, LLC.8-K001-1489510.79/19/22
10.25Additional Call Option Transaction Confirmation, dated as of September 14, 2022 between Sarepta Therapeutics, Inc. and Barclays Bank PLC.8-K001-1489510.89/19/22
10.26Additional Call Option Transaction Confirmation, dated as of September 14, 2022 between Sarepta Therapeutics, Inc. and Goldman Sachs & Co. LLC.8-K001-1489510.99/19/22
10.27Additional Call Option Transaction Confirmation, dated as of September 14, 2022 between Sarepta Therapeutics, Inc. and Mizuho Markets Americas LLC.8-K001-1489510.109/19/22
10.28Additional Call Option Transaction Confirmation, dated as of September 14, 2022 between Sarepta Therapeutics, Inc. and Morgan Stanley & Co. LLC.8-K001-1489510.119/19/22
10.29Additional Call Option Transaction Confirmation, dated as of September 14, 2022 between Sarepta Therapeutics, Inc. and RBC Capital markets, LLC.8-K001-1489510.129/19/22
10.30†Sarepta Therapeutics, Inc. 2018 Equity Incentive Plan10-Q001-1489510.18/8/18
10.31†Letter Agreement between Douglas S. Ingram and Sarepta Therapeutics, Inc. dated June 26, 201810-Q001-1489510.48/8/18

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10.32†Form of Restricted Stock Unit Award Agreement under Sarepta Therapeutics, Inc. 2014 Employment Commencement Incentive Plan10-Q001-1489510.58/8/18
10.33†Amendment No. 2 to the Sarepta Therapeutics, Inc. 2014 Employment Commencement Incentive Plan10-Q001-1489510.68/8/18
10.34†Form of Stock Option Award Agreement under Sarepta Therapeutics, Inc. 2018 Equity Incentive Plan10-Q001-1489510.110/31/18
10.35†Form of Restricted Stock Award Agreement under Sarepta Therapeutics, Inc. 2018 Equity Incentive Plan10-Q001-1489510.210/31/18
10.36†Form of Restricted Stock Unit Award Agreement under Sarepta Therapeutics, Inc. 2018 Equity Incentive Plan10-Q001-1489510.310/31/18
10.37†Form of Stock Appreciation Right Award Agreement under Sarepta Therapeutics, Inc. 2018 Equity Incentive Plan10-Q001-1489510.410/31/18
10.38†Form of Performance-Based Restricted Stock Unit Award Agreement under Sarepta Therapeutics, Inc. 2018 Equity Incentive Plan10-Q001-1489510.105/4/22
10.39†Amendment to Restricted Stock Award Agreement between Douglas S. Ingram and Sarepta Therapeutics, Inc. dated December 17, 201810-K001-1489510.752/28/19
10.40^Amendment No. 1 to License Agreement between Sarepta Therapeutics, Inc. and ST International Holdings Two, Inc. on the one hand and BioMarin Leiden Holding BV, BioMarin Nederlands BV and BioMarin Technologies BV on the other hand10-Q001-1489510.18/7/19
10.41†Amendment No. 1 to the Sarepta Therapeutics, Inc. Amended and Restated 2013 Employment Stock Purchase Plan (as Amended and Restated on June 27, 2016)10-Q001-1489510.48/7/19
10.42Letter Agreement between Sarepta Therapeutics, Inc. and Myonexus Therapeutics, Inc. dated February 26, 201910-Q001-1489510.15/8/19
10.43†Form of Executive Vice President Severance Letter Agreement10-Q001-1489510.25/8/19
10.44†Form of Executive Vice President Change in Control and Severance Agreement10-Q001-1489510.35/8/19
10.45^License, Collaboration, and Option Agreement between Sarepta Therapeutics Three, LLC and F. Hoffman-La Roche Ltd dated December 21, 201910-K001-1489510.512/26/20
10.46†Director Compensation Policy10-K001-1489510.552/26/20
10.47†Amendment No. 2 to the Sarepta Therapeutics, Inc. 2014 Employment Commencement Incentive Plan8-K001-1489510.12/21/20
10.48†Amendment No. 1 to the Sarepta Therapeutics, Inc. 2018 Equity Incentive Plan8-K001-1489510.16/8/2020
10.49†Amendment No. 2 to the Sarepta Therapeutics, Inc. 2018 Equity Incentive Plan10-Q001-1489510.18/2/2022
10.50†Promotion Letter dated December 14, 2020 by and between Sarepta Therapeutics, Inc. and Louise Rodino-Klapac10-K001-1489510.593/1/21

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10.51†Offer Letter dated April 19, 2018 by and between Sarepta Therapeutics, Inc. and Louise Rodino-Klapac10-K001-1489510.603/1/21
10.52†Promotion Letter dated December 14, 2020 by and between Sarepta Therapeutics, Inc. and Ian M. Estepan10-K001-1489510.613/1/21
10.53†Offer Letter dated by December 18, 2014 and between Sarepta Therapeutics, Inc. and Ian M. Estepan10-K001-1489510.623/1/21
10.54Amendment no. 1 dated October 23, 2020 to the License, Collaboration, and Option Agreement between Sarepta Therapeutics Three, LLC and F. Hoffman-La Roche Ltd dated December 21, 201910-Q001-1489510.18/4/21
10.55Amendment no. 14 dated October 31, 2022 to the License, Collaboration, and Option Agreement between Sarepta Therapeutics Three, LLC and F. Hoffman-La Roche Ltd, dated December 21, 201910-K001-1489510.742/28/24
10.56^Amendment No. 2, dated November 17, 2021 to License Agreement between Sarepta Therapeutics, Inc. and ST International Holdings Two, Inc. on the one hand and BioMarin Leiden Holding BV, BioMarin Nederlands BV and BioMarin Technologies BV on the other hand10-K001-1489510.663/1/22
10.57†Letter Agreement, dated November 18, 2022, between Sarepta Therapeutics, Inc. and Douglas S. Ingram10-K001-1489510.722/28/23
10.58†^Omnibus Equity Award Agreement, dated as of December 7, 2025, between the Company and Douglas S. Ingram8-K001-1489510.112/8/25
10.59†General Release and Separation and Consulting Agreement with Dallan Murray10-Q001-1489510.111/6/25
10.60†General Release and Separation and Consulting Agreement with Bilal Arif10-Q001-1489510.211/6/25
10.61^Amended and Restated Lead DMD ProductManufacturing and Supply Agreement betweenCatalent Maryland, Inc. and Sarepta Therapeutics Three, LLC10-Q001-1489510.18/2/23
10.62^Exclusive License Agreement between the Research Institute at Nationwide Children's Hospital and Sarepta Therapeutics, Inc., dated October 8, 201810-Q001-1489510.28/2/23
10.63^First Amendment to the Amended and Restated Lead DMD Product Manufacturing & Supply Agreement between Catalent Maryland, Inc. and Sarepta Therapeutics Three, LLC10-Q001-1489510.58/2/23
10.64†Amendment No. 2 to the Sarepta Therapeutics, Inc. Amended and Restated 2013 Employee Stock Purchase Plan8-K001-1489510.26/9/23
10.65†Amendment No. 3 to the Sarepta Therapeutics, Inc. Amended and Restated 2013 Employee Stock Purchase Plan8-K001-1489510.26/6/25
10.66†Amendment No. 3 to the Sarepta Therapeutics, Inc.2018 Equity Incentive Plan8-K001-1489510.16/9/23

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10.67†Amendment No. 4 to the Sarepta Therapeutics, Inc. 2018 Equity Incentive Plan8-K001-1489510.16/6/25
10.66^First Amendment, dated May 29,2019, to the Exclusive License Agreement betweenResearch Institute at Nationwide Children's Hospitaland Sarepta Therapeutics, Inc.10-Q001-1489510.38/2/23
10.67^Second Amendment, dated July 11, 2023,to the Exclusive License Agreement betweenResearch Institute at Nationwide Children's Hospitaland Sarepta Therapeutics, Inc.10-Q001-1489510.48/2/23
10.68Credit Agreement, dated February 13, 2025, among Sarepta Therapeutics, Inc., Sarepta Therapeutics Investments, Inc., JPMorgan Chase Bank, N.A., as administrative agent, and the lenders party thereto8-K001-1489510.12/14/25
10.69First Amendment to Credit Agreement, dated December 18, 2025, among Sarepta Therapeutics, Inc., JPMorgan Chase Bank, N.A., as administrative agent, and the lenders party theretoX
10.70^Exclusive License and Collaboration Agreement, dated November 25, 2024, between Sarepta Therapeutics, Inc. and Arrowhead Pharmaceuticals, Inc.10-K001-1489510.672/28/25
19.1Sarepta Therapeutics, Inc. Insider Trading Policy10-K001-1489519.12/28/25
21.1Subsidiaries of the Registrant.X
23.1Consent of Independent Registered Public Accounting Firm.X
24.1Power of Attorney (contained on signature page).X
31.1Certification of the Company’s President and Chief Executive Officer, Douglas S. Ingram, pursuant to Section 302 of the Sarbanes-Oxley Act of 2002.X
31.2Certification of the Company’s Executive Vice President, Chief Financial Officer, Ryan Wong, pursuant to Section 302 of the Sarbanes-Oxley Act of 2002.X
32.1**Certification of the Company’s President and Chief Executive Officer, Douglas S. Ingram, pursuant to Section 906 of the Sarbanes-Oxley Act of 2002.X
32.2**Certification of the Company’s Executive Vice President, Chief Financial Officer, Ryan Wong, pursuant to Section 906 of the Sarbanes-Oxley Act of 2002.X
97.1Sarepta Therapeutics Inc.'s Policy for Recoupment of Incentive Compensation10-K001-1489510.772/28/24
101.INSInline XBRL Instance Document - the instance document does not appear in the Interactive Data File as its XBRL tags are embedded within the Inline XBRL document.X

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101.SCHInline XBRL Taxonomy Extension Schema With Embedded Linkbase DocumentsX
104Cover Page Interactive Data File (embedded within the Inline XBRL document)X

† Indicates management contract or compensatory plan, contract or arrangement.

^ Certain identified information has been excluded from the exhibit because it is both (i) not material and (ii) would be competitively harmful if publicly disclosed.

  • Confidential treatment has been granted for portions of this exhibit.

** Furnished herewith. This exhibit shall not be deemed “filed” for purposes of Section 18 of the Securities Exchange Act of 1934, or otherwise subject to the liability of that Section. Such exhibit shall not be deemed incorporated into any filing under the Securities Act of 1933 or the Securities Exchange Act of 1934.

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