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Lantheus Holdings, Inc.

For the period ended Dec 31, 2025. Filed Feb 26, 2026.

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A company's yearly report to the SEC, with audited financial statements. It is the fullest account a company gives of its business, its finances and the risks it sees.

FY2025 · Filed Feb 26, 2026

LNTH$101.62+0.6%Stored close · as of Nov 10, 2026

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Contents

Item 15. Exhibits and Financial Statement Schedules

(a)(1) Financial Statements

The following consolidated financial statements of Lantheus Holdings, Inc. are filed as part of this Annual Report on Form 10-K under Part II, Item 8. Financial Statements and Supplementary Data:

Page
Report of Independent Registered Public Accounting Firm (PCAOB ID No. 34)82
Consolidated Balance Sheets84
Consolidated Statements of Operations85
Consolidated Statements of Comprehensive Income86
Consolidated Statements of Changes in Stockholders’ Equity87
Consolidated Statements of Cash Flows88
Notes to Consolidated Financial Statements90

(a)(2) Schedules

All schedules are omitted because they are not applicable, not required, or because the required information is included in the consolidated financial statements or notes thereto.

(a)(3) Exhibits

EXHIBIT INDEX

Incorporated by Reference
ExhibitNumberDescription of ExhibitsFormFileNumberExhibitFiling Date
2.1††#Agreement and Plan of Merger, dated as of January 27, 2025, by and among Lantheus Medical Imaging, Inc., Project Hazel Merger Sub, Inc., Evergreen Theragnostics, Inc., Shareholder Representative Services LLC and, for purposes of Section 11.2 only, Lantheus Holdings, Inc.8-K001-365692.1January 28, 2025
3.1Amended and Restated Certificate of Incorporation of Lantheus Holdings, Inc.8-K001-365693.1April 27, 2018
3.2Amended and Restated Bylaws of Lantheus Holdings, Inc.8-K001-365693.2May 5, 2025
4.1Common Stock Certificate.8-K001-365694.1June 30, 2015
4.2*Description of Registrant’s Securities
4.3Indenture, dated as of December 8, 2022, between Lantheus Holdings, Inc., as Issuer, Lantheus Medical Imaging, Inc., as Guarantor, and U.S. Bank Trust Company, National Association, as Trustee8-K001-365694.1December 8, 2022
10.1+2015 Equity Incentive Plan of Lantheus Holdings, Inc.S-8333-2052114.1June 26, 2015
10.2+Form of 2015 Restricted Stock Agreement of Lantheus Holdings, Inc.S-1333-19699810.38June 24, 2015
10.3+Form of 2015 Option Award Agreement of Lantheus Holdings, Inc.S-1333-19699810.39June 24, 2015
10.4+Amendment to Lantheus Holdings, Inc. 2015 Equity Incentive Plan.8-K001-3656910.1April 28, 2016
10.5+Second Amendment to Lantheus Holdings, Inc. 2015 Equity Incentive Plan8-K001-3656910.1April 28, 2017
10.6+Form of Severance Agreement (executives with existing employment agreements).10-K001-3656910.70February 20, 2019
10.7+Form of Severance Agreement (executives without existing employment agreements).10-K001-3656910.71February 20, 2019
10.8+Third Amendment to Lantheus Holdings, Inc. 2015 Equity Incentive Plan10-Q001-3656910.1April 30, 2019
10.9+Fourth Amendment to Lantheus Holdings, Inc. 2015 Equity Incentive Plan10-Q001-3656910.2July 25, 2019
10.10+Lantheus Holdings, Inc. 2005 Stock Incentive Plan (f/k/a Progenics Pharmaceuticals, Inc. 2005 Stock Incentive Plan).S-8333-2394914.4June 26, 2020
10.11+Lantheus Holdings, Inc. 2018 Performance Incentive Plan (f/k/a Progenics Pharmaceuticals, Inc. 2018 Performance Incentive Plan).S-8333-2394914.5June 26, 2020
10.12Lease, dated December 31, 2015, between the Registrant and WTC TOWER 1 LLC.8-K000-2314310.46 (21)January 5, 2016
10.13+Fifth Amendment to Lantheus Holdings, Inc. 2015 Equity Incentive Plan8-K001-3656910.1April 29, 2021
10.14††Manufacturing and Supply Agreement, effective as of February 23, 2022, by and between Lantheus Medical Imaging, Inc. and Jubilant HollisterStier LLC.10-Q001-3656910.1April 29, 2022
10.15Form of Restricted Stock Unit Award Agreement (Employee Time-Based Vesting) of Lantheus Holdings, Inc.10-Q001-3656910.2April 29, 2022
10.16Form of Restricted Stock Unit Award Agreement (Relative Total Shareholder Return Performance-Based Vesting) of Lantheus Holdings, Inc.10-Q001-3656910.3April 29, 2022
10.17Form of Stock Option Award Agreement (Time Vesting) of Lantheus Holdings, Inc.10-Q001-3656910.4April 29, 2022
10.18Sixth Amendment to Lantheus Holdings, Inc. 2015 Equity Incentive Plan8-K001-3656910.1May 2, 2022
10.19††License and Collaboration Agreement, dated as of November 11, 2022, by and between Point Biopharma, Inc., and Lantheus Two, LLC.8-K000-3656910.1November 14, 2022
10.20Credit Agreement dated as of December 2, 2022 by and among Citizens Bank, N.A., as administrative agent and collateral agent, each of the lenders from time to time party thereto, Lantheus Medical Imaging, Inc., as borrower, and Lantheus Holdings, Inc.8-K001-3656910.1December 5, 2022
10.21+Lantheus Holdings, Inc. 2023 Employee Stock Purchase Plan8-K001-3656910.1May 1, 2023
10.22††Office Lease by and between Lantheus Medical and 201 Burlington Road Owner, LLC dated February 14, 2022 (the “Lease”); as amended by the First Amendment To Lease dated May 4, 202310-Q001-3656910.1August 3, 2023
10.23First Amendment to License and Collaboration Agreement (PNT-2002), dated as of January 31, 2024, by and between POINT Biopharma, Inc. and Lantheus Two, LLC and Lantheus Medical Imaging, Inc.10-Q001-3656910.1May 2, 2024
10.24Seventh Amendment to Lantheus Holdings, Inc. 2015 Equity Incentive Plan8-K001-3656910.1April 29, 2024
10.25††Second Amendment to Lease dated as of October 3, 202410-K001-3656910.32February 26, 2025
10.26Eighth Amendment to Lantheus Holdings, Inc. 2015 Equity Incentive Plan10-Q001-3656910.1November 6, 2024
10.27First Amendment to Credit Agreement, dated December 19, 2024, among Lantheus Medical Imaging Inc., Lantheus Holdings, Inc., the lenders and other parties party thereto and Citizens Bank N.A., as administrative and collateral agent8-K001-3656910.1December 23, 2024
Incorporated by Reference
ExhibitNumberDescription of ExhibitsFormFileNumberExhibitFiling Date
10.28+Form of Indemnification Agreement10-K001-3656910.35February 26, 2025
10.29+Nonqualified Deferred Compensation Plan10-K001-3656910.36February 26, 2025
10.30††Sale and Purchase Agreement, dated as of January 12, 2025, by and among Life Medical Group Limited and Life Healthcare Group Holdings Limited and Lantheus Radiopharmaceuticals UK Limited and Lantheus Medical Imaging Inc.10-K001-3656910.37February 26, 2025
10.31Third Amendment to Lease dated as of February 14, 2025, by and between Lantheus Medical and 201 Burlington Road Owner, LLC10-Q001-3656910.1May 7, 2025
10.32+Ninth Amendment to Lantheus Holdings, Inc. 2015 Equity Incentive Plan10-Q001-3656910.1August 6, 2025
10.33#Deed of Amendment and Restatement Relating to a Sale and Purchase Agreement entered into July 21, 2025, by and among Life Medical Group Limited and Life Healthcare Group Holdings Limited and Lantheus10-Q001-3656910.1November 6, 2025
10.34+*Consulting Agreement, effective as of November 6, 2025, by and between Brian Markison and Lantheus Medical Imaging Inc.
10.35+*Retirement and Separation Agreement, effective as of November 6, 2025, by and between Brian Markison and Lantheus Medical Imaging Inc.
10.36+*Employment Agreement, effective November 7, 2025, by and between Lantheus Medical Imaging, Inc. and Mary Anne Heino
19.1Policy on Insider Trading and Communications with the Public10-K001-3656919.1February 26, 2025
21.1*Subsidiaries of Lantheus Holdings, Inc.
23.1*Consent of Independent Registered Public Accounting Firm.
24.1*Power of Attorney (included as part of the signature page hereto).
31.1*Certification of Chief Executive Officer pursuant to Exchange Act Rule 13a-14(a).
31.2*Certification of Chief Financial Officer pursuant to Exchange Act Rule 13a-14(a).
32.1**Certification pursuant to 18 U.S.C. Section 1350.
97.1Amended and Restated Executive Compensation Clawback Policy10-K001-3656997.1February 26, 2025
101.INS*Inline XBRL Instance Document – the instance document does not appear in the Interactive Data File because its XBRL tags are embedded within the Inline XBRL document
101.SCH*Inline XBRL Taxonomy Extension Schema Document With Embedded Linkbase Documents
104*Cover Page Interactive Data File (embedded within the Inline XBRL document)
  • Filed herewith.

** Furnished herewith.

†† Portions of this exhibit have been omitted for confidential treatment pursuant to Item 601(b)(10)(iv) of Regulation S-K.

  • Indicates management contract or compensatory plan or arrangement.

† Confidential treatment requested as to certain portions, which portions have been filed separately with the Securities and Exchange Commission.

Pursuant to Item 601(b)(2)(ii) of Regulation S-K promulgated by the SEC, certain portions of this exhibit have been redacted because the Company customarily and actually treats such omitted information as private or confidential and because such omitted information is not material.

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